Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Ayodele, Alaiya"'
Autor:
Marwa Elfoly, Jumanah Y. Mirza, Ayodele Alaiya, Amal A. Al-Hazzani, Asma Tulbah, Monther Al-Alwan, Hazem Ghebeh
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background PD-L1 intrinsically promotes tumor progression through multiple mechanisms, which potentially leads to resistance to anti-PD-1/PD-L1 therapies. The intrinsic effect of PD-L1 on breast cancer (BC) cell proliferation has not been fu
Externí odkaz:
https://doaj.org/article/f566893f991f499ea6cf467f7bb0d987
Autor:
Ayodele Alaiya, Bothina Mohammed Alharbi, Zakia Shinwari, Mamoon Rashid, Tahani H. Albinhassan, Abderrezak Bouchama, Mai B. Alwesmi, Sameer Mohammad, Shuja Shafi Malik
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6787 (2024)
Heat stroke, a hazardous hyperthermia-related illness, is characterized by CNS injury, particularly long-lasting brain damage. A root cause for hyperthermic neurological damage is heat-induced proteotoxic stress through protein aggregation, a known c
Externí odkaz:
https://doaj.org/article/75a83c66f3b645ef9111730f0513ec53
Autor:
Abdullah Al-Dhfyan, Ayodele Alaiya, Falah Al-Mohanna, Mohamed W Attwa, Abdullah F AlAsmari, Saleh A Bakheet, Hesham M. Korashy
Publikováno v:
Journal of Advanced Research, Vol 50, Iss , Pp 177-192 (2023)
Introduction: Activating the aryl hydrocarbon receptor upon exposure to environmental pollutants promotes development of breast cancer stem cell (CSCs). BCL-2 family proteins protect cancer cells from the apoptotic effects of chemotherapeutic drugs.
Externí odkaz:
https://doaj.org/article/077aed138a744559b39a47fddf63d0c3
Publikováno v:
Cells, Vol 13, Iss 11, p 932 (2024)
Periodontal disease is characterized by inflammation and bone loss. Central to its pathogenesis is the dysregulated inflammatory response, complicating regenerative therapies. Mesenchymal stem cells (MSCs) hold significant promise in tissue repair an
Externí odkaz:
https://doaj.org/article/da310b530b0b41ff8030df601b9ac3aa
Autor:
Eid A. Al-Mutairy, Somaya Al Qattan, Mohammed Khalid, Azizah A. Al-Enazi, Maher M. Al-Saif, Faiqa Imtiaz, Khushnooda Ramzan, Vineesh Raveendran, Ayodele Alaiya, Brian F. Meyer, Sergei P. Atamas, Kate S. Collison, Khalid S. Khabar, Jeffrey D. Hasday, Futwan Al-Mohanna
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Patients with digenic S100A3 and S100A13 mutations exhibited an atypical and progressive interstitial pulmonary fibrosis, with impaired intracellular calcium homeostasis and mitochondrial dysfunction. Here we provide direct evidence of a causative ef
Externí odkaz:
https://doaj.org/article/9beaf0213feb4ac5b53d12e80ef852b3
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 2, Pp 1373-1386 (2023)
Osteopetrosis is a rare hereditary illness generated by failure in osteoclasts resulting in elevated bone densities. Patients with osteopetrosis possess several complications, like dental caries, earlier teeth loss, delayed eruption, malformed crowns
Externí odkaz:
https://doaj.org/article/83e412c666984e82a9ceffc10af1f674
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13841 (2023)
Osteopetrosis is a rare inherited disease caused by osteoclast failure, resulting in increasing bone density in humans. Patients with osteopetrosis possess several dental and cranial complications. Since carbonic anhydrase II (CA-II) deficiency is a
Externí odkaz:
https://doaj.org/article/b67ba30c5d7748a8bda3e3547dd6559d
Publikováno v:
Genetics Research, Vol 2023 (2023)
Background. Sex and gender have a large impact in human health and disease prediction. According to genomic/genetics, men differ from women by a limited number of genes in Y chromosome, while the phenotypes of the 2 sexes differ markedly. Methods. In
Externí odkaz:
https://doaj.org/article/a5fe17d1ace74824af52584743c0e274
Autor:
Qamraa H. Al‐Qahtani, Walid N. Moghrabi, Suhad Al‐Yahya, Latifa Al‐Haj, Maher Al‐Saif, Linah Mahmoud, Falah Al‐Mohanna, Norah Al‐Souhibani, Ayodele Alaiya, Edward Hitti, Khalid S. A. Khabar
Publikováno v:
Molecular Oncology, Vol 15, Iss 8, Pp 2120-2139 (2021)
Dysfunctions in post‐transcriptional control are observed in cancer and chronic inflammatory diseases. Here, we employed a kinome inhibitor library (n = 378) in a reporter system selective for 3′‐untranslated region–AU‐rich elements (ARE).
Externí odkaz:
https://doaj.org/article/9b16b262c2074fbf8d05f478d8b4d7df
Quantitative proteomics analysis reveals unique but overlapping protein signatures in HIV infections
Autor:
Maha Al-Mozaini, Alhusain Alzahrani, Ibtihaj Alsharif, Zakia Shinwari, Magid Halim, Abdullah Alhokail, Abdulrahman Alrajhi, Ayodele Alaiya
Publikováno v:
Journal of Infection and Public Health, Vol 14, Iss 6, Pp 795-802 (2021)
Background: Human immunodeficiency virus-1 (HIV-1) exploits human host factors to complete its life cycle. Hence, discovery of HIV-regulated host proteins markers would better our understanding of the virus life-cycle and its contribution to pathogen
Externí odkaz:
https://doaj.org/article/938e7045eea24731b5fae6b32523dbd0