Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Aynur Bekar"'
Publikováno v:
Annals of Hepatology, Vol 13, Iss 6, Pp 788-795 (2014)
Background and aim. Multiple risk factors lead to hepatocellular carcinoma (HCC) including viral infections, mutation and single nucleotide polymorphisms (SNPs). Interleukin 28B (IL28B) gene rs12979860 polymorphism has been shown to be associated wit
Externí odkaz:
https://doaj.org/article/85a0f92722e34a399293686784656de4
Autor:
Berrin Yalınbaş Kaya, Ersin Akgöllü, Oğuz Üsküdar, Süleyman Bayram, Hikmet Akkiz, Aynur Bekar, Yakup Ülger, Sedef Kuran, Ercan Çınar, Selçuk Yıldırım, Mahmut Şansal
Publikováno v:
Meta Gene
Background: Reactive oxygen species (ROS) can oxidize biological molecules that mediate carcinogenesis by causing metabolic malfunction and damage to DNA. Human serum paraoxonases (PON1, PON2 and PON3) play a role in antioxidant defense and protect t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e9590d76d5a390fed89b023bf40852
Publikováno v:
Cancer Epidemiology. 36:453-457
WOS: 000309818500018 PubMed ID: 22521562 Background: The cell cycle checkpoint kinase 2 (CHEK2) protein participates in the DNA damage response in many cell types. Germline mutations in CHEK2 (1100delC, IVS2+1G>A and I157T) have been impaired serine/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc4277d78cf350b84465ac66494d520
https://doi.org/10.1016/j.canep.2012.03.008
https://doi.org/10.1016/j.canep.2012.03.008
Publikováno v:
Molecular and Cellular Biochemistry. 347:201-208
PubMedID: 21042835 Cyclooxygenase-2 (COX-2) influences carcinogenesis through immune response suppression, apoptosis inhibition, regulation of angiogenesis and tumor cell invasion, and metastasis. It is now well established that COX-2 is overexpresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f013c2d3020e3fade39dee675f07fead
https://doi.org/10.1007/s11010-010-0629-9
https://doi.org/10.1007/s11010-010-0629-9
Publikováno v:
Cancer Epidemiology. 34:448-452
PubMedID: 20447891 Background: The mouse double minute 2 (MDM2) gene represents one of the central nodes in the p53 pathway. A naturally occurring T/G single nucleotide polymorphism (SNP) in the intronic promoter of MDM2, SNP309 (rs2279744), was show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3d36035568476abe5c7198cb4ea658
https://doi.org/10.1016/j.canep.2010.04.008
https://doi.org/10.1016/j.canep.2010.04.008
Publikováno v:
Cancer Epidemiology. 34:298-302
PubMedID: 20347627 Background: A common G to A polymorphism (G870A) in the splice donor region of exon 4 of cyclin D1 (CCND1) gene generates two mRNAs (cyclin D1a and D1b) through an alternative splicing at the site of this polymorphism. Cyclin D1a a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb29df7be64f572c58845e1eeccf418b
https://doi.org/10.1016/j.canep.2010.02.011
https://doi.org/10.1016/j.canep.2010.02.011
Publikováno v:
The Turkish Journal of Gastroenterology. 21:29-33
Proton pompa inhibitörler, büyük ölçüde karaciğerde bulunan sitokrom P450 2C19 (CYP2C19) enzimi tarafından metabolize edilirler. Sitokrom P450 2C19 enziminin fonksiyonel polimorfizmi proton pompa inhibitörleri asit'baskılayıcı etkilerini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff34561e47d5e22c46ca25b397195b73
https://doi.org/10.4318/tjg.2010.0043
https://doi.org/10.4318/tjg.2010.0043
Autor:
Haluk Demiryürek, Ahmet Taner Sümbül, Ersin Akgöllü, Süleyman Bayram, Hikmet Akkiz, Figen Doran, Burhan Özdil, Aynur Bekar
Publikováno v:
Cancer Epidemiology. 33:261-264
Background: A common G to A polymorphism (G870A) in the splice donor region of exon 4 of cyclin D1 (CCND1) gene generates two mRNAs (cyclin D1a and D1b) through an alternative splicing at the site of this polymorphism. Cyclin D1a and b proteins diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4642ffa0abfeff45944461a0d42cc8bd
https://doi.org/10.1016/j.canep.2009.06.001
https://doi.org/10.1016/j.canep.2009.06.001
Autor:
Ersin Akgöllü, Oğuz Üsküdar, Berrin Yalınbaş Kaya, Macit Sandikci, Aynur Bekar, Yakup Ülger, Sedef Kuran, Hikmet Akkiz, Selçuk Yıldırım
PubMedID: 25857516 Background and objective: The hepatitis C virus (HCV) which infects 3% of the world's population is a global challenge. Recently, genome-wide association studies (GWAS) have identified that the IL28B gene rs8099917 polymorphism was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9810b7299c1c0e7b8f669c89a37982
https://hdl.handle.net/20.500.12605/19435
https://hdl.handle.net/20.500.12605/19435
Publikováno v:
Annals of Hepatology, Vol 13, Iss 6, Pp 788-795 (2014)
Scopus-Elsevier
Scopus-Elsevier
PubMedID: 25332265 Background and aim. Multiple risk factors lead to hepatocellular carcinoma (HCC) including viral infections, mutation and single nucleotide polymorphisms (SNPs). Interleukin 28B (IL28B) gene rs12979860 polymorphism has been shown t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2d694007f32859417b0b1c3111d5f7
https://pubmed.ncbi.nlm.nih.gov/25332265
https://pubmed.ncbi.nlm.nih.gov/25332265