Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Aynara C. Wulsin"'
Autor:
Aynara C Wulsin, Ana Franco-Villanueva, Christian Romancheck, Rachel L Morano, Brittany L Smith, Benjamin A Packard, Steve C Danzer, James P Herman
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197955 (2018)
Clinical data suggest that the neuroendocrine stress response is chronically dysregulated in a subset of patients with temporal lobe epilepsy (TLE), potentially contributing to both disease progression and the development of psychiatric comorbidities
Externí odkaz:
https://doaj.org/article/7111acca85a54c3d9a3a8245c7ea2b97
Autor:
Venkat Suru, Steve C. Danzer, Kimberly L. Kraus, Kevin D. Gaitonde, Benjamin A. Packard, Aynara C. Wulsin, Salwa R. Arafa, James P. Herman
Publikováno v:
Exp Neurol
Objective Glucocorticoid levels rise rapidly following status epilepticus and remain elevated for weeks after the injury. To determine whether glucocorticoid receptor activation contributes to the pathological sequelae of status epilepticus, mice wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cb6c4bca42de5f13de3d34516f1c8a
https://europepmc.org/articles/PMC8169587/
https://europepmc.org/articles/PMC8169587/
Autor:
Valentina Ghisays, Christina M. Estrada, Sarah Berman, Joshua Streicher, Aynara C. Wulsin, Matia B. Solomon, Jody L. Caldwell, Elizabeth T. Nguyen
Publikováno v:
Physiology & Behavior. 178:82-92
Aberrant glucocorticoid secretion is implicated in the pathophysiology of stress-related disorders (i.e., depression, anxiety). Glucocorticoids exert biological effects via mineralocorticoid (MR) and glucocorticoid (GR) receptors. Previous data from
Autor:
Benjamin A. Packard, Evelin M. Cotella, Maureen E. Fitzgerald, Rachel Morano, Susan E. Martelle, Rachel D. Moloney, Paige Lemen, Aynara C. Wulsin, James P. Herman
Adolescent animals are vulnerable to the effects of stress on brain development. We hypothesized that long-term effects of adolescent chronic stress are mediated by glucocorticoid receptor (GR) signaling. We used a specific GR modulator (CORT108297)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ba499796ed34a2cb0af65bafcd1744
Publikováno v:
Physiology & Behavior. 166:22-31
Epilepsy is a common neurological disease, affecting 2.4 million people in the US. Among the many different forms of the disease, temporal lobe epilepsy (TLE) is one of the most frequent in adults. Recent studies indicate the presence of a hyperactiv
Publikováno v:
Psychoneuroendocrinology. 65:109-117
Adolescence is a period of substantial neuroplasticity in stress regulatory neurocircuits. Chronic stress exposure during this period leads to long-lasting changes in neuroendocrine function and emotional behaviors, suggesting adolescence may be a cr
Autor:
Rachel Morano, Rachel D. Moloney, James P. Herman, Evelin M. Cotella, Maureen Fitzgerald, Benjamin A. Packard, Susan M. Martelle, Paige Lemen, Aynara C. Wulsin
Publikováno v:
Psychoneuroendocrinology
Adolescent animals are vulnerable to the effects of stress on brain development. We hypothesized that long-term effects of adolescent chronic stress are mediated by glucocorticoid receptor (GR) signaling. We used a specific GR modulator (CORT108297)
Autor:
Benjamin A. Packard, James P. Herman, Christian Romancheck, Rachel Morano, Steve C. Danzer, Brittany L. Smith, Ana Franco-Villanueva, Aynara C. Wulsin
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197955 (2018)
PLoS ONE
PLoS ONE
Clinical data suggest that the neuroendocrine stress response is chronically dysregulated in a subset of patients with temporal lobe epilepsy (TLE), potentially contributing to both disease progression and the development of psychiatric comorbidities
Autor:
Brent Myers, Brittany L. Kopp, Ryan Makinson, Jessie R. Scheimann, Sriparna Ghosal, James P. Herman, Jessica M. McKlveen, Aynara C. Wulsin
Publikováno v:
Comprehensive Physiology
The hypothalamo-pituitary-adrenocortical (HPA) axis is required for stress adaptation. Activation of the HPA axis causes secretion of glucocorticoids, which act on multiple organ systems to redirect energy resources to meet real or anticipated demand