Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Aymn E. Rashad"'
Publikováno v:
Molecules, Vol 19, Iss 5, Pp 5459-5469 (2014)
4-Imino-1-p-tolyl-1,4-dihydropyrazolo[3,4-d]pyrimidin-5-ylamine (2) and (1-p-tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-hydrazine (3) were prepared starting from ethyl 4-cyano-1-p-tolyl-1H-pyrazol-5-ylimidoformate (1). The structure of compound 3 was co
Externí odkaz:
https://doaj.org/article/43167983071e4a3d98893aca1f24cb0b
Publikováno v:
Archiv der Pharmazie. 347:559-565
5-Amino-1-p-tolyl-1H-pyrazole-4-carbonitrile (1) was used for the preparation of some novel pyrazoles and pyrazolo[3,4-d]pyrimidines 2-10. Moreover, the cytotoxicity and in vitro anticancer activities of the prepared compounds were also assessed agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e05103723a53eacfaa47c9c522b89aa
https://doi.org/10.1002/ardp.201400064
https://doi.org/10.1002/ardp.201400064
Publikováno v:
Molecules
Volume 19
Issue 5
Pages: 5459-5469
Molecules, Vol 19, Iss 5, Pp 5459-5469 (2014)
Volume 19
Issue 5
Pages: 5459-5469
Molecules, Vol 19, Iss 5, Pp 5459-5469 (2014)
4-Imino-1-p-tolyl-1,4-dihydropyrazolo[3,4-d]pyrimidin-5-ylamine (2) and (1-p-tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-hydrazine (3) were prepared starting from ethyl 4-cyano-1-p-tolyl-1H-pyrazol-5-ylimidoformate (1). The structure of compound 3 was co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b117d9f36d6114dde6cb23bb7097f475
http://europepmc.org/articles/PMC6271700
http://europepmc.org/articles/PMC6271700
Publikováno v:
Journal of Heterocyclic Chemistry. 51:899-905
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b241c2a99af86f9a2e3cb1acd1229498
https://doi.org/10.1002/jhet.1724
https://doi.org/10.1002/jhet.1724
Autor:
Aymn E. Rashad, Mahmoud El-Shahat, Ahmed H. Shamroukh, Józef Drabowicz, Hatem S. Ali, Mamdouh M. Ali
Publikováno v:
European Journal of Medicinal Chemistry. 69:521-526
Some novel N -nicotinonitrile derivatives 3 – 14 have been synthesized starting with compound 1 . The key step of this work is the coupling between compound 1 and activated sugars to afford the corresponding cyclic nucleosides 3 – 6 . Moreover, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b794122e7f04e10b389122435f48be1
https://doi.org/10.1016/j.ejmech.2013.09.005
https://doi.org/10.1016/j.ejmech.2013.09.005
Publikováno v:
Journal of Heterocyclic Chemistry. 50:758-765
Novel β-enaminonitrile of 1-(6-phenyl-pyridazin-3-yl)-pyrazole derivative 2 was formed using (6-phenyl-pyridazin-3-yl)-hydrazine (1) and 2-ethoxymethylene-malononitrile. The β-enaminonitrile derivative 2 was in turn used as precursors for the prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30cabc44c89bba24510b1fcb76432b21
https://doi.org/10.1002/jhet.1550
https://doi.org/10.1002/jhet.1550
Autor:
Husam A. Ghanem, Aymn E. Rashad, Mohamed A. Ali, Omar R. Alfarouk, Sahar A. Shoman, Ahmed Barakat
Publikováno v:
Egyptian Academic Journal of Biological Sciences, G. Microbiology. 5:25-33
Thirteen chemical compounds belonging to the fused heterocyclic pyrimidines were synthesized and screened in order to assay their antiviral activity against the avian influenza virus (H5N1) A/Chicken/Qalubiya/1/2006(H5N1) by plaque reduction assay on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c882754551f21a77943edbc345f9550
https://doi.org/10.21608/eajbsg.2013.16642
https://doi.org/10.21608/eajbsg.2013.16642
Autor:
Ahmed H. Shamroukh, Ahmed F. El-Farargy, Maher A. El-Hashash, Mowafia A. Salama, Ahmed Mostafa, Mahmoud El-Shahat, Aymn E. Rashad, Nabil M. Yousif
Publikováno v:
Journal of Heterocyclic Chemistry. 49:1130-1135
Pyridine and fused pyridines derivatives are interesting compounds with diverse chemical properties and pharmacological activities. Herein, the synthesis and antiviral evaluation of some new pyridines are described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4cd97d318d453e87885f1c747d47967
https://doi.org/10.1002/jhet.966
https://doi.org/10.1002/jhet.966
Autor:
Ahmed H. Shamroukh, Hatem S. Ali, Aymn E. Rashad, Abeer E. Mahmoud, Mowafia A. Salama, Mahmoud El-Shahat, Nabil M. Yousif, Mamdouh M. Ali
Publikováno v:
Archiv der Pharmazie. 345:729-738
A series of novel substituted pyrimidinones and fused pyrimidinones (compounds 3-18) were synthesized starting with oxiranylmethanone 2. The in vitro cytotoxicity against a human breast adenocarcinoma (MCF-7) cell line was investigated and most of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59c181586c985ba0686a0cdd3b1ad07
https://doi.org/10.1002/ardp.201200119
https://doi.org/10.1002/ardp.201200119