Low Cell Number Proteomic Analysis Using In-Cell Protease Digests Reveals a Robust Signature for Cell Cycle State Classification

Autor: Van Kelly, Aymen S al-Rawi, Georg Kustatscher, David A Lewis, Tony Ly

Publikováno v: Kelly, V, Al-Rawi, A, Lewis, D, Kustatscher, G & Ly, T 2022, ' Low cell number proteomic analysis using in-cell protease digests reveals a robust signature for cell cycle state classification ', Molecular and Cellular Proteomics, vol. 21, no. 1, 100169 . https://doi.org/10.1016/j.mcpro.2021.100169
Molecular & Cellular Proteomics : MCP

Comprehensive proteome analysis of rare cell phenotypes remains a significant challenge. We report a method for low cell number MS-based proteomics using protease digestion of mildly formaldehyde-fixed cells in cellulo, which we call the “in-cell d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9f08dd143b45d961982ffdce6ad432
https://doi.org/10.1016/j.mcpro.2021.100169