Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Ayman K. Hamouda"'
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-18 (2018)
Abstract Positive allosteric modulators (PAMs) of nicotinic acetylcholine receptors (nAChRs) have potential therapeutic application in neuropathologies associated with decrease in function or loss of nAChRs. In this study, we characterize the pharmac
Externí odkaz:
https://doaj.org/article/ea32213fb70144b6b14014e1daf21895
Autor:
Nathalia M. Pinheiro, Rosana Banzato, Iolanda Tibério, Marco A. M. Prado, Vânia F. Prado, Ayman K. Hamouda, Carla M. Prado
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7552 (2021)
(1) Background: The lung cholinergic pathway is important for controlling pulmonary inflammation in acute lung injury, a condition that is characterized by a sudden onset and intense inflammation. This study investigated changes in the expression lev
Externí odkaz:
https://doaj.org/article/c5233f264f2c4be8808aa66bb02961d9
Autor:
Farah Deba, Kara Ramos, Matthew Vannoy, Kemburli Munoz, Lois S. Akinola, M. Imad Damaj, Ayman K. Hamouda
Publikováno v:
Molecules, Vol 25, Iss 12, p 2923 (2020)
Neuronal nicotinic acetylcholine receptor (nAChR)-based therapeutics are sought as a potential alternative strategy to opioids for pain management. In this study, we examine the antinociceptive effects of 3-(2-chlorophenyl)-5-(5-methyl-1-(piperidin-4
Externí odkaz:
https://doaj.org/article/b51df15f92344ed789de3fb3583a5d8a
Autor:
Yasmin Alkhlaif, Medhat El-Halawany, Wisam Toma, Abigail Park, Ayman K. Hamouda, M. Imad Damaj
Publikováno v:
Neuroscience Letters. 807:137279
Publikováno v:
The FASEB Journal. 36
Publikováno v:
Biophysical Journal. 122:395a
Autor:
Roberta Sessa Stilhano, Tiago Nicoliche, Robertha Mariana Rodrigues Lemes, Wothan Tavares-de-Lima, Kil Lee, Cynthia Bartholomeo, Ayman K. Hamouda, Nathalia Pinheiro, Iolanda F.L.C. Tibério, Carla Máximo Prado, Rodrigo Portes Ureshino, Tamires Alves
Publikováno v:
Airway cell biology and immunopathology.
Autor:
Ayman K. Hamouda, Rosana Banzato, Marco A. M. Prado, Iolanda F.L.C. Tibério, Carla Máximo Prado, Vania F. Prado, Nathalia Montouro Pinheiro
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7552, p 7552 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 14
International Journal of Molecular Sciences
Volume 22
Issue 14
(1) Background: The lung cholinergic pathway is important for controlling pulmonary inflammation in acute lung injury, a condition that is characterized by a sudden onset and intense inflammation. This study investigated changes in the expression lev
Autor:
Malia Bautista, Asti Jackson, Christie D. Fowler, Lois S. Akinola, Yen-Chu Chen, Yasmin Alkhlaif, Ayman K. Hamouda, Moriah Carper, Ganesh A. Thakur, M. Imad Damaj, Wisam Toma, Sumanta Garai
Publikováno v:
Neuropharmacology
The low sensitivity (α4)3(β2)2 (LS) and high sensitivity (α4)2(β2)3 (HS) nAChR isoforms may contribute to a variety of brain functions, pathophysiological processes, and pharmacological effects associated with nicotine use. In this study, we exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac14a85b6795faed13b6d4dae5e1e2cc
https://escholarship.org/uc/item/5193j2fz
https://escholarship.org/uc/item/5193j2fz
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 65:128701
A series of racemic benzofurans bearing N-methyl-2-pyrrolidinyl residue at C(2) or C(3) has been synthesized and tested for affinity at the α4β2 and α3β4 nicotine acetylcholine receptors (nAChRs). As previously reported for the benzodioxane based