Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ayman Abo Elmaaty"'
Autor:
Tarfah Al-Warhi, Ahmed A. Al-Karmalawy, Ayman Abo Elmaaty, Maha A. Alshubramy, Marwa Abdel-Motaal, Taghreed A. Majrashi, Medhat Asem, Ahmed Nabil, Wagdy M. Eldehna, Marwa Sharaky
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 176-191 (2023)
Herein, a set of pyridine and pyrimidine derivatives were assessed for their impact on the cell cycle and apoptosis. Human breast cancer (MCF7), hepatocellular carcinoma (HEPG2), larynx cancer (HEP2), lung cancer (H460), colon cancers (HCT116 and Cac
Externí odkaz:
https://doaj.org/article/adf517f35b1249309f2559b7c318ae10
Autor:
Mai A. E. Mourad, Ayman Abo Elmaaty, Islam Zaki, Ahmed A. E. Mourad, Amal Hofni, Ahmed E. Khodir, Esam M. Aboubakr, Ahmed Elkamhawy, Eun Joo Roh, Ahmed A. Al-Karmalawy
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Topoisomerases II are ubiquitous enzymes with significant genotoxic effects in many critical DNA processes. Additionally, epidermal growth factor receptor (EGFR) plays pivotal role in tumour growth and angiogenesis. A novel series of naphtho[2',3':4,
Externí odkaz:
https://doaj.org/article/6f8700c95e194931b430928931ecacbe
Autor:
Faten Farouk, Ayman Abo Elmaaty, Ahmed Elkamhawy, Haytham O. Tawfik, Radwan Alnajjar, Mohammed A. S. Abourehab, Mohamed A. Saleh, Wagdy M. Eldehna, Ahmed A. Al‐Karmalawy
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Topoisomerase II (TOP-2) is a promising molecular target for cancer therapy. Numerous antibiotics could interact with biologically relevant macromolecules and provoke antitumor potential. Herein, molecular docking studies were used to investigate the
Externí odkaz:
https://doaj.org/article/a1c855bf5ade4c9380cb028408c47807
Autor:
Marwa I. Abd El-Hamid, Reham M. El-Tarabili, Mosa M. Bahnass, Mohammed Abdulrahman Alshahrani, Ahmed Saif, Khairiah Mubarak Alwutayd, Fatmah Ahmed Safhi, Abdallah Tageldein Mansour, Noaf Abdullah N. Alblwi, Mohammed M. Ghoneim, Ayman Abo Elmaaty, Helal F. Al-harthi, Mahmoud M. Bendary
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionThere is an urgent need to develop therapeutic options for biofilm-producing Staphylococcus aureus (S. aureus). Therefore, the renewed interest in essential oils (EOs), especially carvacrol, linalool and eugenol, has attracted the attenti
Externí odkaz:
https://doaj.org/article/c8b6bc5b148141f496e2ab3210808235
Autor:
Mohamed Elagawany, Ayman Abo Elmaaty, Ahmed Mostafa, Noura M. Abo Shama, Eman Y. Santali, Bahaa Elgendy, Ahmed A. Al-Karmalawy
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2112-2132 (2022)
The global outbreak of the COVID-19 pandemic provokes scientists to make a prompt development of new effective therapeutic interventions for the battle against SARS-CoV-2. A new series of N-(5-nitrothiazol-2-yl)-carboxamido derivatives were designed
Externí odkaz:
https://doaj.org/article/be13a2cc18784d8c9feb702560387273
Autor:
Rogy R. Ezz Eldin, Marwa A. Saleh, Mohammad Hayal Alotaibi, Reem K. Alsuair, Yahya A. Alzahrani, Feras A. Alshehri, Amany F. Mohamed, Shaimaa M. Hafez, Azza Ali Althoqapy, Seham K. Khirala, Mona M. Amin, Yousuf A. F, Azza H. AbdElwahab, Mohamed S. Alesawy, Ayman Abo Elmaaty, Ahmed A. Al-Karmalawy
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1098-1119 (2022)
Herein, a series of N'-benzylidene-3,4-dimethoxybenzohydrazide derivatives were designed and synthesised to target the multidrug efflux pump (MATE). The antibacterial activities were screened against S. aureus, Acinetobacter, S. typhi, E. coli, and P
Externí odkaz:
https://doaj.org/article/c03d2a86a53447f6abf2741a1f54b2f8
Autor:
Rogy R. Ezz Eldin, Marwa A. Saleh, Sefat A. Alwarsh, Areej Rushdi, Azza Ali Althoqapy, Hoda S. El Saeed, Ayman Abo Elmaaty
Publikováno v:
Pharmaceuticals, Vol 16, Iss 9, p 1247 (2023)
Herein, a series of new isatin derivatives was designed and synthesized (1–9) as broad-spectrum antiviral agents. Consequently, the antiviral activities of the synthesized compounds (1–9) were pursued against three viruses, namely influenza virus
Externí odkaz:
https://doaj.org/article/2d450734bc3b406db8c2b396ad3164d2
Autor:
Ayman Abo Elmaaty, Khaled M. Darwish, Amani Chrouda, Amira A. Boseila, Mohamed A. Tantawy, Sameh S. Elhady, Afzal B. Shaik, Muhamad Mustafa, Ahmed A. Al-karmalawy
Publikováno v:
ACS Omega, Vol 7, Iss 1, Pp 875-899 (2021)
Externí odkaz:
https://doaj.org/article/5accf66cdd9f49249feaacbb6be3bdd8
Autor:
Mohamed F. Ghaly, Marzough Aziz Albalawi, Mahmoud M. Bendary, Ahmed Shahin, Mohamed A. Shaheen, Abeer F. Abu Eleneen, Mohammed M. Ghoneim, Ayman Abo Elmaaty, Mohamed F. M. Elrefai, Sawsan A. Zaitone, Amira I. Abousaty
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 464 (2023)
The worldwide crises from multi-drug-resistant (MDR) bacterial infections are pushing us to search for new alternative therapies. The renewed interest in medicinal plants has gained the attention of our research group. Tamarindus indica L. (T. indica
Externí odkaz:
https://doaj.org/article/fdb8fd6a9dcb49d3b741e02c53252981
Autor:
Atef A. El-Hela, Marwa S. Abu Bakr, Mostafa M. Hegazy, Mohammed A. Dahab, Ayman Abo Elmaaty, Adel Ehab Ibrahim, Sami El Deeb, Hatem S. Abbass
Publikováno v:
Scientia Pharmaceutica, Vol 91, Iss 1, p 7 (2023)
Virtual screening of the potential lead chemotherapeutic phytochemicals from medicinal plants has useful application in the field of in-silico modelling and computer-based drug design by orienting and scoring ligands in the active binding site of a t
Externí odkaz:
https://doaj.org/article/0ab7b634f7ed4eff8be2b813a850def0