Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Ayman, Al Haj Zen"'
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
Metastasis is the cause of most triple-negative breast cancer deaths, yet anti-metastatic therapeutics remain limited. To develop new therapeutics to prevent metastasis, pathophysiologically relevant assays that recapitulate tumor microenvironment is
Externí odkaz:
https://doaj.org/article/534cc96f5fa046c0b8841d8bb61f1b54
Autor:
Dalal Al‐Sharshani, Dinesh Velayutham, Muthanna Samara, Reham Gazal, Ayman Al Haj Zen, Mohamed A. Ismail, Mahmoud Ahmed, Gheyath Nasrallah, Salma Younes, Nasser Rizk, Sara Hammuda, M. Walid Qoronfleh, Thomas Farrell, Hatem Zayed, Palli Valapila Abdulrouf, Manar AlDweik, John Paul Ben Silang, Alaa Rahhal, Rana Al‐Jurf, Ahmed Mahfouz, Amar Salam, Hilal Al Rifai, Nader I. Al‐Dewik
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 8, Pp n/a-n/a (2023)
Abstract Background Dyslipidemia is recognized as one of the risk factors of cardiovascular diseases (CVDs), type 2 diabetes mellitus (T2DM), and non‐alcoholic fatty liver disease (NAFLD). Objective The study aimed to investigate the association be
Externí odkaz:
https://doaj.org/article/6ccecb89661f4863820c4206c89e0b14
Autor:
Yosra Bejaoui, Sara Alresheq, Sophie Durand, Marie Vilaire-Meunier, Louise Maillebouis, Ayman Al Haj Zen, André Mégarbané, Nady El Hajj
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundDown Syndrome (DS) is the most common chromosome anomaly in humans and occurs due to an extra copy of chromosome 21. The malignancy profile in DS is unique, since DS patients have a low risk of developing solid tumors such as breast cancer
Externí odkaz:
https://doaj.org/article/50d1f8dddaac4b9fbd822ef72c563368
Autor:
Hend Salah Fayed, Mouayad Zuheir Bakleh, Jasni Viralippurath Ashraf, Alison Howarth, Daniel Ebner, Ayman Al Haj Zen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14410 (2023)
The impairment in microvascular network formation could delay the restoration of blood flow after acute limb ischemia. A high-content screen of a GSK-published kinase inhibitor library identified a set of ROCK inhibitor hits enhancing endothelial net
Externí odkaz:
https://doaj.org/article/ca7a451713d04f85a821d90f8f25b725
Autor:
Andrea Martello, David Mellis, Marco Meloni, Alison Howarth, Daniel Ebner, Andrea Caporali, Ayman Al Haj Zen
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 29-43 (2018)
Endothelial cell (EC) proliferation is a crucial event in physiological and pathological angiogenesis. MicroRNAs (miRNAs) have emerged as important modulators of the angiogenic switch. Here we conducted high-content screening of a human miRNA mimic l
Externí odkaz:
https://doaj.org/article/dc8cb931a63c4b539b7ae99df0efb97c
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4891 (2022)
Angiogenesis is a critical cellular process toward establishing a functional circulatory system capable of delivering oxygen and nutrients to the tissue in demand. In vitro angiogenesis assays represent an important tool for elucidating the biology o
Externí odkaz:
https://doaj.org/article/303426cbbb9a49af8ad5760c6a252420
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10585 (2021)
Arteriogenesis is one of the primary physiological means by which the circulatory collateral system restores blood flow after significant arterial occlusion in peripheral arterial disease patients. Vascular smooth muscle cells (VSMCs) are the predomi
Externí odkaz:
https://doaj.org/article/ab9f33995d5540028027ebbd1a526a0c
Autor:
Micol Marchetti, Marco Meloni, Maryam Anwar, Ayman Al-Haj-Zen, Graciela Sala-Newby, Sadie Slater, Kerrie Ford, Andrea Caporali, Costanza Emanueli
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1733 (2020)
MicroRNAs (miRs) regulate complex processes, including angiogenesis, by targeting multiple mRNAs. miR-24-3p-3p directly represses eNOS, GATA2, and PAK4 in endothelial cells (ECs), thus inhibiting angiogenesis during development and in the infarcted h
Externí odkaz:
https://doaj.org/article/38fb0d5612c2421f9272bd17edcb7504
Autor:
Heba Z. Sailem, Ayman Al Haj Zen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Angiogenesis plays a key role in several diseases including cancer, ischemic vascular disease, and Alzheimer’s disease. Chemical genetic screening of endothelial tube formation provides a robust approach for identifying signalling components that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b93f0543b9d71473f3c96f6cd4e1ae97
http://link.springer.com/article/10.1038/s41598-020-70440-0
http://link.springer.com/article/10.1038/s41598-020-70440-0
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10585, p 10585 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Arteriogenesis is one of the primary physiological means by which the circulatory collateral system restores blood flow after significant arterial occlusion in peripheral arterial disease patients. Vascular smooth muscle cells (VSMCs) are the predomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e833d5bd188938d871e085b33c8426ab
https://www.mdpi.com/1422-0067/22/19/10585
https://www.mdpi.com/1422-0067/22/19/10585