Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Aylin S. Ülkü"'
Autor:
Lynn B. Eckert, Channing J. Der, Gretchen A. Repasky, Hong Zhou, Carolyn I. Sartor, Aylin S. Ülkü, Aidan McFall
Publikováno v:
Cancer Research. 64:4585-4592
Although mutated forms of ras are not associated with the majority of breast cancers (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd07db01999d26b2bc0224c45ac198e0
https://doi.org/10.1158/0008-5472.can-04-0396
https://doi.org/10.1158/0008-5472.can-04-0396
Autor:
Aylin S. Ülkü, Chad A. Ellis, Geoffrey J. Clark, Candice Elam, Michele D. Vos, Barbara J. Taylor
Publikováno v:
Journal of Biological Chemistry. 278:28045-28051
Ras proteins regulate a wide range of biological processes by interacting with a broad assortment of effector proteins. Although activated forms of Ras are frequently associated with oncogenesis, they may also provoke growth-antagonistic effects. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a585978594938f4769a5a440ed413ea5
https://doi.org/10.1074/jbc.m300554200
https://doi.org/10.1074/jbc.m300554200
Autor:
Channing J. Der, Aylin S. Ülkü
Publikováno v:
Cancer Treatment and Research ISBN: 1402073402
While our understanding of Ras signaling is significant and many of the signaling components and pathways activated by Ras have been delineated, it is also likely that much remains to be determined. The discovery of additional downstream effectors of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6158972c6be7d0eecdc067aa75976013
https://doi.org/10.1007/0-306-48158-8_8
https://doi.org/10.1007/0-306-48158-8_8
Publisher Summary This chapter describes the application of various cellular assays for examining the growth transformation caused by GPCR oncogenes that promote the aberrant activation of Rho family small GTPases. A critical step in the validation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::871b32345ac4cefedca837ba2465f7c3
https://doi.org/10.1016/b978-012164730-8/50042-3
https://doi.org/10.1016/b978-012164730-8/50042-3
Publikováno v:
International journal of cancer. 112(2)
Ras expression induces increased expression and altered targeting of lysosomal proteases in multiple cell types, but the specific downstream cytoplasmic signaling pathways mediating these changes have not been identified. In this study, we compared t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ebf0d8e199cbeaa9826a08b6485740
https://pubmed.ncbi.nlm.nih.gov/15352030
https://pubmed.ncbi.nlm.nih.gov/15352030
Publisher Summary This chapter discusses the mammalian expression vectors for Ras family proteins. The chapter presents some observations concerning the strengths and weaknesses of several mammalian protein expression vectors, both commercially avail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11093efb755a0252daad9716089611f6
https://doi.org/10.1016/s0076-6879(01)32189-4
https://doi.org/10.1016/s0076-6879(01)32189-4
Autor:
Aylin S. Ülkü, Kelley Rogers-Graham, Channing J. Der, Aidan McFall, Que T. Lambert, Andrea Kusa
Activated Ras, but not Raf, causes transformation of RIE-1 rat intestinal epithelial cells, demonstrating the importance of Raf-independent effector signaling in mediating Ras transformation. To further assess the contribution of Raf-dependent and Ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a061beaa7d541cff05c4ceb78c3b4e76