Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Aylin R Rodan"'
Autor:
Prathibha Yarikipati, Sima Jonusaite, John M Pleinis, Carihann Dominicci Cotto, David Sanchez-Hernandez, Daryl E Morrison, Suhani Goyal, Jeffrey Schellinger, Clothilde Pénalva, Jennifer Curtiss, Aylin R Rodan, Andreas Jenny
Publikováno v:
PLoS Genetics, Vol 19, Iss 10, p e1010975 (2023)
WNK (With no Lysine [K]) kinases have critical roles in the maintenance of ion homeostasis and the regulation of cell volume. Their overactivation leads to pseudohypoaldosteronism type II (Gordon syndrome) characterized by hyperkalemia and high blood
Externí odkaz:
https://doaj.org/article/b6adfc2ea48b4ecd889356660b33c85a
Autor:
Dana M Talsness, Katie G Owings, Emily Coelho, Gaelle Mercenne, John M Pleinis, Raghavendran Partha, Kevin A Hope, Aamir R Zuberi, Nathan L Clark, Cathleen M Lutz, Aylin R Rodan, Clement Y Chow
Publikováno v:
eLife, Vol 9 (2020)
N-Glycanase 1 (NGLY1) is a cytoplasmic deglycosylating enzyme. Loss-of-function mutations in the NGLY1 gene cause NGLY1 deficiency, which is characterized by developmental delay, seizures, and a lack of sweat and tears. To model the phenotypic variab
Externí odkaz:
https://doaj.org/article/b15615d75fd24af79e4e3c0481b7aa57
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137465 (2015)
Responses to the effects of ethanol are highly conserved across organisms, with reduced responses to the sedating effects of ethanol being predictive of increased risk for human alcohol dependence. Previously, we described that regulators of actin dy
Externí odkaz:
https://doaj.org/article/4e90f1bd5cfd4527842fd197322389ef
Autor:
Collin B. Merrill, Austin B. Montgomery, Miguel A. Pabon, Andrey A. Shabalin, Aylin R. Rodan, Adrian Rothenfluh
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Gene regulation is critical for proper cellular function. Next-generation sequencing technology has revealed the presence of regulatory networks that regulate gene expression and essential cellular functions. Studies investigating
Externí odkaz:
https://doaj.org/article/9c6a6656befe4806903a1fb4a4db4f16
Autor:
Enrique Balderas, David R. Eberhardt, Sandra Lee, John M. Pleinis, Salah Sommakia, Anthony M. Balynas, Xue Yin, Mitchell C. Parker, Colin T. Maguire, Scott Cho, Marta W. Szulik, Anna Bakhtina, Ryan D. Bia, Marisa W. Friederich, Timothy M. Locke, Johan L. K. Van Hove, Stavros G. Drakos, Yasemin Sancak, Martin Tristani-Firouzi, Sarah Franklin, Aylin R. Rodan, Dipayan Chaudhuri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Mitochondrial complex I deficiency is frequent in congenital, neurologic and cardiovascular disease. Here the authors demonstrate that Complex I stimulates the turnover of a mitochondrial calcium channel, which becomes stabilized during Complex I def
Externí odkaz:
https://doaj.org/article/c2ef9f77a9ef4d22aad9d8b4d27239a7
Autor:
Puskar Mishra, Shany E. Yang, Austin B. Montgomery, Addison R. Reed, Aylin R. Rodan, Adrian Rothenfluh
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background Proper regulation of feeding is important for an organism’s well-being and survival and involves a motivational component directing the search for food. Dissecting the molecular and neural mechanisms of motivated feeding behavio
Externí odkaz:
https://doaj.org/article/7237a38c1e8f426e8b64b27b0e3b498c
Autor:
Kelly A. Hyndman, Elena Isaeva, Oleg Palygin, Luciano D. Mendoza, Aylin R. Rodan, Alexander Staruschenko, Jennifer S. Pollock
Publikováno v:
Physiological Reports, Vol 9, Iss 20, Pp n/a-n/a (2021)
Abstract The nitric oxide (NO)‐generating enzyme, NO synthase‐1β (NOS1β), is essential for sodium (Na+) homeostasis and blood pressure control. We previously showed that collecting duct principal cell NOS1β is critical for inhibition of the ep
Externí odkaz:
https://doaj.org/article/9fc56951e59441bfb00452897d4b5cca
Autor:
Elizabeth J, Goldsmith, Aylin R, Rodan
Publikováno v:
Annual Review of Physiology. 85:383-406
The with no lysine (K) (WNK) kinases are an evolutionarily ancient group of kinases with atypical placement of the catalytic lysine and diverse physiological roles. Recent studies have shown that WNKs are directly regulated by chloride, potassium, an
Autor:
Collin B. Merrill, Iris Titos, Miguel A. Pabon, Austin B. Montgomery, Aylin R. Rodan, Adrian Rothenfluh
SummaryTheDrosophilabrain contains tens of thousands of distinct cell types. Thousands of different transgenic lines reproducibly target specific neuron subsets, yet most still express in several cell types. Furthermore, most lines were developed wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eba36d279c15595acef4effcc68dcc7b
https://doi.org/10.1101/2023.04.14.536950
https://doi.org/10.1101/2023.04.14.536950