Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Aylin C. Morris-Davies"'
Autor:
Katrin Rittinger, Veronique Schaeffer, Evangelos Christodoulou, Marios G. Koliopoulos, N.R. Brown, Aylin C. Morris-Davies, Ivan Dikic, Benjamin Stieglitz, Steven Howell, Rohini R. Rana
Publikováno v:
Nature
Linear ubiquitin chains are important regulators of cellular signalling pathways that control innate immunity and inflammation through nuclear factor (NF)-κB activation and protection against tumour necrosis factor-α-induced apoptosis. They are syn
Autor:
Marios G. Koliopoulos, Benjamin Stieglitz, Aylin C. Morris-Davies, Katrin Rittinger, Evangelos Christodoulou
Publikováno v:
EMBO Reports
LUBAC synthesizes linear ubiquitin chains via a thioester intermediate The N-terminus of the LUBAC catalytic subunit is shown to be autoinhibitory and counteracted by the other subunits of the complex. Linear ubiquitination proceeds through a thioest
Autor:
Frank J. Ivins, Susan J. M. Smith, Mark G. Montgomery, Aylin C. Morris-Davies, Katrin Rittinger, Ian A. Taylor
Publikováno v:
Biochemical Journal
The IKK [IkappaB (inhibitory kappaB) kinase] complex is a key regulatory component of NF-kappaB (nuclear factor kappaB) activation and is responsible for mediating the degradation of IkappaB, thereby allowing nuclear translocation of NF-kappaB and tr