Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Aylin C Hanyaloglu"'
Autor:
Chirine Toufaily, Jérôme Fortin, Carlos AI Alonso, Evelyne Lapointe, Xiang Zhou, Yorgui Santiago-Andres, Yeu-Farn Lin, Yiming Cui, Ying Wang, Dominic Devost, Ferdinand Roelfsema, Frederik Steyn, Aylin C Hanyaloglu, Terence E Hébert, Tatiana Fiordelisio, Derek Boerboom, Daniel J Bernard
Publikováno v:
eLife, Vol 10 (2021)
Gonadotropin-releasing hormone (GnRH) is the primary neuropeptide controlling reproduction in vertebrates. GnRH stimulates follicle-stimulating hormone (FSH) and luteinizing hormone (LH) synthesis via a G-protein-coupled receptor, GnRHR, in the pitui
Externí odkaz:
https://doaj.org/article/67a8eb78b0ce46eab129601c15478f79
Autor:
Maaike Schilperoort, Andrea D van Dam, Geerte Hoeke, Irina G Shabalina, Anthony Okolo, Aylin C Hanyaloglu, Lea H Dib, Isabel M Mol, Natarin Caengprasath, Yi‐Wah Chan, Sami Damak, Anne Reifel Miller, Tamer Coskun, Bharat Shimpukade, Trond Ulven, Sander Kooijman, Patrick CN Rensen, Mark Christian
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 3, Pp 1-18 (2018)
Abstract Brown adipose tissue (BAT) activation stimulates energy expenditure in human adults, which makes it an attractive target to combat obesity and related disorders. Recent studies demonstrated a role for G protein‐coupled receptor 120 (GPR120
Externí odkaz:
https://doaj.org/article/435be6144c2f46c4be6f9f0833c44ebc
Autor:
Paul J. Brighton, Abigail R. Walker, Oliver Mann, Chow-Seng Kong, Emma S. Lucas, Pavle Vrljicak, Jan J. Brosens, Aylin C. Hanyaloglu
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111170- (2024)
Summary: Decidualization denotes the differentiation of endometrial stromal cells into specialized decidual cells, essential for embryo implantation and pregnancy. The process requires coordination of progesterone and cAMP signaling, which converge o
Externí odkaz:
https://doaj.org/article/721ff821f6494eebbf78c87130c099a0
Autor:
Jennifer Ho, Nicholas Puoplo, Namrata Pokharel, Aanya Hirdaramani, Aylin C. Hanyaloglu, Chia-Wei Cheng
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Food-gene interaction has been identified as a leading risk factor for inflammatory bowel disease (IBD) and colorectal cancer (CRC). Accordingly, nutrigenomics emerges as a new approach to identify biomarkers and therapeutic targets for these two str
Externí odkaz:
https://doaj.org/article/ebfebc311ef1452dbd694dd180caddff
Autor:
Lucia Riaposova, Sung Hye Kim, Aylin C. Hanyaloglu, Lynne Sykes, David A. MacIntyre, Phillip R. Bennett, Vasso Terzidou
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionPreterm birth is one of the major causes of neonatal morbidity and mortality across the world. Both term and preterm labour are preceded by inflammatory activation in uterine tissues. This includes increased leukocyte infiltration, and su
Externí odkaz:
https://doaj.org/article/472ba91a1a5548bdad4bb81d45dcd9e4
Autor:
Matilda Shackley, Yue Ma, Edward W. Tate, Alastair J. H. Brown, Gary Frost, Aylin C. Hanyaloglu
Publikováno v:
Frontiers in Nutrition, Vol 7 (2020)
The short chain fatty acids (SCFAs) acetate, butyrate and propionate, are produced by fermentation of non-digestible carbohydrates by the gut microbiota and regulate appetite, adiposity, metabolism, glycemic control, and immunity. SCFAs act at two di
Externí odkaz:
https://doaj.org/article/31540f5f1b5e4233a5314fe94deefec9
Autor:
Natarin Caengprasath, Noemi Gonzalez-Abuin, Maria Shchepinova, Yue Ma, Asuka Inoue, Edward W. Tate, Gary Frost, Aylin C. Hanyaloglu
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101449- (2020)
Summary: The ability of propionate, a short-chain fatty acid produced from the fermentation of non-digestible carbohydrates in the colon, to stimulate the release of anorectic gut hormones, such as glucagon like peptide-1 (GLP-1), is an attractive ap
Externí odkaz:
https://doaj.org/article/2b75dd03f2474139ae9df1079d47dafb
Autor:
Caroline M. Gorvin, Angela Rogers, Benoit Hastoy, Andrei I. Tarasov, Morten Frost, Silvia Sposini, Asuka Inoue, Michael P. Whyte, Patrik Rorsman, Aylin C. Hanyaloglu, Gerda E. Breitwieser, Rajesh V. Thakker
Publikováno v:
Cell Reports, Vol 22, Iss 4, Pp 1054-1066 (2018)
Spatial control of G-protein-coupled receptor (GPCR) signaling, which is used by cells to translate complex information into distinct downstream responses, is achieved by using plasma membrane (PM) and endocytic-derived signaling pathways. The roles
Externí odkaz:
https://doaj.org/article/a620aa50861b4760af796663dffcd895
Autor:
Silvia Sposini, Frederic G. Jean-Alphonse, Mohammed A. Ayoub, Affiong Oqua, Camilla West, Stuart Lavery, Jan J. Brosens, Eric Reiter, Aylin C. Hanyaloglu
Publikováno v:
Cell Reports, Vol 21, Iss 10, Pp 2855-2867 (2017)
Summary: Endocytic trafficking is a critical mechanism for cells to decode complex signaling pathways, including those activated by G-protein-coupled receptors (GPCRs). Heterogeneity in the endosomal network enables GPCR activity to be spatially rest
Externí odkaz:
https://doaj.org/article/ed50dbb194264e8e94d6b99f22063168
Autor:
Niamh Sayers, Aylin C. Hanyaloglu
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Models of G protein-coupled receptor (GPCR) signaling have dramatically altered over the past two decades. Indeed, GPCRs such as the follicle-stimulating hormone receptor (FSHR) have contributed to these new emerging models. We now understand that re
Externí odkaz:
https://doaj.org/article/1872f9772e6a46b7994b8e83984967f2