Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Aylin Alkan"'
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Rectal cancer constitutes approximately one-third of all colorectal cancers and contributes to considerable mortality globally. In contrast to colon cancer, the standard treatment for localized rectal cancer often involves neoadjuvant chemor
Externí odkaz:
https://doaj.org/article/fb4ca781472941b2899c29022c0bef26
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-17 (2021)
Biomarker Research
Biomarker Research
Rectal cancer constitutes approximately one-third of all colorectal cancers and contributes to considerable mortality globally. In contrast to colon cancer, the standard treatment for localized rectal cancer often involves neoadjuvant chemoradiothera
Autor:
Ali Cagir, Hasan Ozan Otaş, Aylin Alkan, Meltem Kutluer, Hakkı Çetinkaya, Mehmet Salih Yildiz
Publikováno v:
Bioorganic chemistry. 103
In this work, 2'-alkoxymethyl substituted klavuzon derivatives were prepared starting from 2-methyl-1-naphthoic acid in eight steps. Anticancer potencies of the synthesized compounds were evaluated by performing MTT cell viability test over cancerous
Autor:
Aylin Alkan, İsmail Akçok, Ayhan Şen, Hasan Ozan Otaş, Ali Cagir, Meltem Kutluer, Tuğçe Kanbur, Murat Delman, Murat Kara
Publikováno v:
Bioorganicmedicinal chemistry. 25(16)
Klavuzons are 6-(naphthalen-1-yl) substituted 5,6-dihydro-2H-pyran-2-one derivatives showing promising antiproliferative activities in variety of cancer cell lines. In this work, racemic syntheses of nine novel 4′-alkyl substituted klavuzon derivat