Nutrient signalling and lysosome positioning crosstalk through a multifunctional protein, Folliculin

Autor: Aylett Chs, de Martín Garrido N

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology

FLCN was identified as the gene responsible for Birt-Hogg-Dube (BHD) syndrome, a hereditary syndrome associated with the appearance of familiar renal oncocytomas. Most mutations affecting FLCN result in the truncation of the protein, and therefore lo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5826073a460333e0e0b15259cded343
http://hdl.handle.net/10044/1/77776

Molecular architecture of the 40S · eIF1 · eIF3 translation initiation complex

Autor: Sali, Andrej, Erzberger, JP, Stengel, F, Pellarin, R, Zhang, S, Schaefer, T, Aylett, CHS, Cimermančič, P, Boehringer, D, Aebersold, R

Publikováno v: Sali, Andrej; Erzberger, JP; Stengel, F; Pellarin, R; Zhang, S; Schaefer, T; et al.(2014). Molecular architecture of the 40S · eIF1 · eIF3 translation initiation complex. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/3c09947r

Eukaryotic translation initiation requires the recruitment of the large, multiprotein eIF3 complex to the 40S ribosomal subunit. We present X-ray structures of all major components of the minimal, six-subunit Saccharomyces cerevisiae eIF3 core. These

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::c1f5fd2e3d1e6589d2d159805156e5f9
http://www.escholarship.org/uc/item/3c09947r

A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate.

Autor: Ramlaul K; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, United Kingdom., Feng Z; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, United Kingdom., Canavan C; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, United Kingdom., de Martín Garrido N; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, United Kingdom., Carreño D; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, United Kingdom., Crone M; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, United Kingdom., Jensen KE; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, United Kingdom., Li B; Hamlyn Centre, Department of Brain Sciences, Imperial College London, London, United Kingdom., Barnett H; Imperial College Advanced Hackspace, Imperial College London, London, United Kingdom., Riglar DT; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, United Kingdom; The Francis Crick Institute, London, United Kingdom., Freemont PS; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, United Kingdom., Miller D; Imperial College Advanced Hackspace, Imperial College London, London, United Kingdom. Electronic address: d.miller@imperial.ac.uk., Aylett CHS; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, United Kingdom. Electronic address: c.aylett@imperial.ac.uk.

Publikováno v: Journal of structural biology [J Struct Biol] 2023 Sep; Vol. 215 (3), pp. 107999. Date of Electronic Publication: 2023 Jul 13.

Correction to 'Structure of the bacteriophage PhiKZ non-virion RNA polymerase'.

Autor: de Martín Garrido N; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, UK., Orekhova M; Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Lai Wan Loong YTE; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, UK., Litvinova A; Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Ramlaul K; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, UK., Artamonova T; Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Melnikov AS; Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Serdobintsev P; St. Petersburg State University, St. Petersburg, Russia., Aylett CHS; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, UK., Yakunina M; Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia.; Sechenov Institute of Evolutionary Physiology and Biochemistry Russian Academy of Sciences, St. Petersburg, Russia.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2021 Oct 11; Vol. 49 (18), pp. 10806.

Structure of the bacteriophage PhiKZ non-virion RNA polymerase.

Autor: deYMartín Garrido N; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, UK., Orekhova M; Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Lai Wan Loong YTE; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, UK., Litvinova A; Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Ramlaul K; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, UK., Artamonova T; Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Melnikov AS; Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Serdobintsev P; St. Petersburg State University, St. Petersburg, Russia., Aylett CHS; Section for Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London, UK., Yakunina M; Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia.; Sechenov Institute of Evolutionary Physiology and Biochemistry Russian Academy of Sciences, St. Petersburg, Russia.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2021 Jul 21; Vol. 49 (13), pp. 7732-7739.