Additional file 2: of FTY720 controls disease severity and attenuates sciatic nerve damage in chronic experimental autoimmune neuritis

Autor: Kremer, Laurent, Taleb, Omar, Boehm, Nelly, Ayikoe Mensah-Nyagan, Trifilieff, Elisabeth, Seze, Jérôme, Brun, Susana

Figure S2. Effect of FTY720 on the clinical course of EAN. Clinical score values were measured in vehicle (white square) and FTY720-treated (black square) rats. Therapeutic injections of FTY720 or vehicle were administrated intraperitoneally from 12

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7c66a617bbd4526951a2b819bff34a

Mechanisms of proteolipid protein mutation-induced oligodendrocyte death : role of endoplasmic reticulum stress and identification of modulatory compounds with high potential for the treatment of dysmyelinating disorders

Autor: Wilding, Anne-Sophie

Publikováno v: Neurosciences. Université de Strasbourg, 2017. Français. ⟨NNT : 2017STRAJ073⟩

Mutations of proteolipid-protein (PLP) cause oligodendrocyte (OL) death and myelin disorders. To contribute to the elucidation of the mechanisms involved, the present PhD work has used 158N (normal) and 158JP (mutated PLP) OL lines, to show the occur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::da80ea88c0d8dd9082dbe1586dc49269
https://theses.hal.science/tel-01707470

Multidisciplinary analysis of biological effects of novel analogs of the neurosteroid allopregnanolone : evidence for a proliferative, neurogenic and neuroprotective action

Autor: Karout, Mona

Publikováno v: Neurobiology. Université de Strasbourg; Albert-Ludwigs-Universität (Freiburg im Breisgau, Allemagne), 2015. English. ⟨NNT : 2015STRAJ056⟩

This PhD work allowed us to successfully characterize structural analogs of allopregnanolone. Some of these analogs showed beneficial effects and advantages with respect to the molecule of reference. In particular, the analog O-allyl-AP stimulates pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::80ec6124bda64f7b7c44774e90c06ea5
https://tel.archives-ouvertes.fr/tel-01376497/file/Karout_Mona_2015_ED414.pdf

Multidisciplinary analysis of biological effects of novel analogs of the neurosteroid allopregnanolone : evidence for a proliferative, neurogenic and neuroprotective action

Autor: Karout, Mona

Publikováno v: Neurobiology. Université de Strasbourg; Albert-Ludwigs-Universität (Freiburg im Breisgau, Allemagne), 2015. English. ⟨NNT : 2015STRAJ056⟩

This PhD work allowed us to successfully characterize structural analogs of allopregnanolone. Some of these analogs showed beneficial effects and advantages with respect to the molecule of reference. In particular, the analog O-allyl-AP stimulates pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::80ec6124bda64f7b7c44774e90c06ea5
https://theses.hal.science/tel-01376497