Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Ayfer Yalcin"'
Autor:
Gokselin Ozgen, Merve Turk Gezer, Guliz Armagan, Petek Ballar Kirmizibayrak, Ayfer Yalcin, Ozgen Ozer, Banu Ozkirim Arslan, Gonul Kayar, Udaya Kumar Dude, Aysegul Kaymak Ozdemir
Publikováno v:
ACS Omega, Vol 9, Iss 16, Pp 18366-18374 (2024)
Externí odkaz:
https://doaj.org/article/03a6f904365a4f3f8e2bab07dd9c9034
Autor:
Guliz Armagan, Yiğit Uyanıkgil, Ezgi Turunc Bayrakdar, Ayfer Yalcin, Lutfiye Kanit, Ersin O. Koylu
Publikováno v:
Cell Biochemistry and Function. 32:557-564
Alzheimer's disease (AD) is the most common form of dementia and is characterized by the presence of senile plaques and neurofibrillary tangles, along with synaptic loss. The underlying mechanisms of AD are not clarified yet, but oxidative stress and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f2f7404a7903aed83e07f23a3d34ae7
https://doi.org/10.1002/cbf.3049
https://doi.org/10.1002/cbf.3049
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 16:695-701
Glutathione (GSH) is a major endogenous antioxidant highly active in human tissues and plays a key role in controlling cellular thiol redox system, maintaining the immune and detoxification system. The determination of GSH levels in tissue is importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f9755867c7b06e9fd8c3049b99d7db8
https://doi.org/10.2174/13862073113169990040
https://doi.org/10.2174/13862073113169990040
Autor:
Adyary Fallarero, Gulsah Bayraktar, Pia Vuorela, Carola Schiller, Ezgi Turunc, Manuel Krug, Sülünay Parlar, Guliz Armagan, Ayfer Yalcin, Vildan Alptüzün, Christoph A. Sotriffer, Kristina Leuner, Daniela Karlsson, Malgorzata Burek, Michaela Prinz, Ulrike Holzgrabe, Ercin Erciyas, Carola Förster
Publikováno v:
European Journal of Pharmaceutical Sciences. 49:603-613
Given the fundamentally multifactorial character of Alzheimer's disease (AD), addressing more than one target for disease modification or therapy is expected to be highly advantageous. Here, following the cholinergic hypothesis, we aimed to inhibit b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a2933633e6fc31f6477b0ff4f6452a
https://doi.org/10.1016/j.ejps.2013.04.024
https://doi.org/10.1016/j.ejps.2013.04.024
Autor:
Guliz Armagan, Lutfiye Kanit, Anna Borsodi, Ayfer Yalcin, Sándor Benyhe, Ezgi Turunc Bayrakdar, Engin Bojnik
Publikováno v:
Epilepsy Research. 105:13-19
The opioid/nociceptin receptors are involved in many neurological disorders such as Alzheimer's disease, Parkinson's disease and epilepsy. Kainic acid (KA) is an analog of the excitatory amino acid transmitter glutamate and the systemic administratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56c518679721c539a213436b36ed09a
https://doi.org/10.1016/j.eplepsyres.2012.12.008
https://doi.org/10.1016/j.eplepsyres.2012.12.008
Autor:
Guliz Armagan, Elena Soddu, Lutfiye Kanit, Paolo Giunchedi, Giovanna Rassu, Yiğit Uyanıkgil, Ayfer Yalcin, Ezgi Turunc Bayrakdar, Elisabetta Gavini
Publikováno v:
Journal of pharmaceutical sciences. 105(8)
β-Amyloid (Aβ) plaques are the key neurotoxic assemblies in Alzheimer disease. It has been suggested that an interaction occurs between membrane cholesterol and Aβ aggregation in the brain. Cyclodextrins can remove cholesterol from cell membranes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d635215ac862cdf5dead9781a538315a
https://pubmed.ncbi.nlm.nih.gov/27353207
https://pubmed.ncbi.nlm.nih.gov/27353207
Publikováno v:
Drug and Chemical Toxicology. 35:393-398
Inflammation is deleterious for organs with reduced capacity of regeneration, such as the brain. Recently, studies have focused on investigating the therapeutic effects of nonsteroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease, Parkinso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c7f5f59b8690796f94978d3836b71d
https://doi.org/10.3109/01480545.2011.633086
https://doi.org/10.3109/01480545.2011.633086
Publikováno v:
Free Radical Research. 46:726-739
Mefenamic acid, a non-steroidal antiinflammatory drug (NSAID), directly and dose-dependently exhibits neuroprotective activity. In our study, we investigated the effects of mefenamic acid against d-serine on oxidative stress in the hippocampus, corte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f864ee190a4fb190e632b1a58d10766
https://doi.org/10.3109/10715762.2012.669836
https://doi.org/10.3109/10715762.2012.669836
Autor:
Ayfer Yalcin, Josephine Lok, Wendy Leung, Song Zhao, Xiaoying Wang, Shuzhen Guo, Klaus van Leyen, Eng H. Lo, Stefanie Pallast
Publikováno v:
Journal of Neurochemistry. 118:248-255
Oxidative stress is a pathway of injury that is common to almost all neurological conditions. Hence, methods to scavenge radicals have been extensively tested for neuroprotection. However, saving neurons alone may not be sufficient in treating CNS di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::235a8596b583e76085ce66f6fbdd0283
https://doi.org/10.1111/j.1471-4159.2011.07294.x
https://doi.org/10.1111/j.1471-4159.2011.07294.x
Publikováno v:
Drug and Chemical Toxicology. 34:129-138
D-serine plays a significant role in neuronal activity, including learning, memory, neuronal migration at developmental stages, and cell-death signaling. It has been also suggested that D-serine can potantiate the neurotoxicity induced by N-methyl-D-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6970b7212ff553e5d67a8bc0376e3a
https://doi.org/10.3109/01480545.2010.494183
https://doi.org/10.3109/01480545.2010.494183