Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ayesha S. Khan"'
Autor:
Akash K. Kaushik, Ali Shojaie, Katrin Panzitt, Rajni Sonavane, Harene Venghatakrishnan, Mohan Manikkam, Alexander Zaslavsky, Vasanta Putluri, Vihas T. Vasu, Yiqing Zhang, Ayesha S. Khan, Stacy Lloyd, Adam T. Szafran, Subhamoy Dasgupta, David A. Bader, Fabio Stossi, Hangwen Li, Susmita Samanta, Xuhong Cao, Efrosini Tsouko, Shixia Huang, Daniel E. Frigo, Lawrence Chan, Dean P. Edwards, Benny A. Kaipparettu, Nicholas Mitsiades, Nancy L. Weigel, Michael Mancini, Sean E. McGuire, Rohit Mehra, Michael M. Ittmann, Arul M. Chinnaiyan, Nagireddy Putluri, Ganesh S. Palapattu, George Michailidis, Arun Sreekumar
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The molecular alterations driving anti-androgen resistance in prostate cancer are unclear. Here, the authors show, using a network-based approach, that inhibition of the hexosamine biosynthetic pathway is necessary to develop resistance and that incr
Externí odkaz:
https://doaj.org/article/928bd0a4d45444ac89e49f796339b9e4
Autor:
Ayesha S. Khan, Daniel E. Frigo
Publikováno v:
Nature Reviews Urology. 14:164-180
The 5'-AMP-activated protein kinase (AMPK) is a master regulator of cellular homeostasis. Despite AMPK's known function in physiology, its role in pathological processes such as prostate cancer is enigmatic. However, emerging evidence is now beginnin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e825bac18642d31ac1173b44515c08fa
https://doi.org/10.1038/nrurol.2016.272
https://doi.org/10.1038/nrurol.2016.272
Autor:
Efrosini Tsouko, Ali Shojaie, Ayesha S. Khan, David A. Bader, Harene Venghatakrishnan, Dean P. Edwards, Ganesh S. Palapattu, Daniel E. Frigo, Vihas T. Vasu, Sean E. McGuire, Rajni Sonavane, Lawrence Chan, Yiqing Zhang, Alexander Zaslavsky, Fabio Stossi, Nagireddy Putluri, Katrin Panzitt, Mohan Manikkam, Nancy L. Weigel, Akash K. Kaushik, Michael Ittmann, Arun Sreekumar, Adam T. Szafran, Nicholas Mitsiades, Stacy M. Lloyd, Xuhong Cao, Benny Abraham Kaipparettu, Arul M. Chinnaiyan, Michael A. Mancini, Subhamoy Dasgupta, Susmita Samanta, Vasanta Putluri, Shixia Huang, George Michailidis, Hangwen Li, Rohit Mehra
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications
Nature Communications
The precise molecular alterations driving castration-resistant prostate cancer (CRPC) are not clearly understood. Using a novel network-based integrative approach, here, we show distinct alterations in the hexosamine biosynthetic pathway (HBP) to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d1b364a8583c64ef551af7dbe0a5e8a
https://doaj.org/article/928bd0a4d45444ac89e49f796339b9e4
https://doaj.org/article/928bd0a4d45444ac89e49f796339b9e4
Autor:
Michael Ittmann, Harene Venghatakrishnan, Ganesh S. Palapattu, Adam T. Szafran, Ali Shojaie, Stacy M. Lloyd, Ayesha S. Khan, George Michailidis, Benny Abraham Kaipparettu, Xuhong Cao, Nancy L. Weigel, Akash K. Kaushik, David A. Bader, Yiqing Zhang, Fabio Stossi, Lawrence Chan, Efrosini Tsouko, Alexander Zaslavsky, Katrin Panzitt, Nicholas Mitsiades, Shixia Huang, Daniel E. Frigo, Vihas T. Vasu, Dean P. Edwards, Vasanta Putluri, Hangwen Li, Arul M. Chinnaiyan, Michael A. Mancini, Subhamoy Dasgupta, Rajni Sonavane, Susmita Samanta, Mohan Manikkam, Nagireddy Putluri, Arun Sreekumar
Publikováno v:
Cancer Research. 76:1056-1056
Prostate Cancer (PCa) is the second highest cause of cancer-related death in men in the US. PCa is androgen dependent when organ-confined and is conventionally treated using surgery or using a combination of anti-androgens and radiation therapy. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::073866cf80ae96629a4e3616aa3f7335
https://doi.org/10.1158/1538-7445.am2016-1056
https://doi.org/10.1158/1538-7445.am2016-1056
Autor:
Ayesha S. Khan, Fatima A. Merchant, Jenny J. Han, Mark A. White, Yan Shi, Daniel E. Frigo, Martyn A. Sharpe, Efrosini Tsouko, Li Xin
Publikováno v:
Oncogenesis
Cancer cells display an increased demand for glucose. Therefore, identifying the specific aspects of glucose metabolism that are involved in the pathogenesis of cancer may uncover novel therapeutic nodes. Recently, there has been a renewed interest i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c709359edd1f96b524b30177f6f482
https://doi.org/10.1038/oncsis.2014.18
https://doi.org/10.1038/oncsis.2014.18