Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ayesha Arefin"'
Autor:
Ayesha Arefin, Melissa Mendoza, Keri Dame, M. Iveth Garcia, David G. Strauss, Alexandre J. S. Ribeiro
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Engineered heart tissues (EHTs) are three-dimensional culture platforms with cardiomyocytes differentiated from human pluripotent stem cells (hPSCs) and were designed for assaying cardiac contractility. For drug development applications
Externí odkaz:
https://doaj.org/article/0caa3dcb1e3c4d56b6be5325f29875c7
Autor:
Andrés Rubiano, Amruta Indapurkar, Ryosuke Yokosawa, Alina Miedzik, Barry Rosenzweig, Ayesha Arefin, Chloe M. Moulin, Keri Dame, Neil Hartman, Donna A. Volpe, Murali K. Matta, David J. Hughes, David G. Strauss, Tomasz Kostrzewski, Alexandre J. S. Ribeiro
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 3, Pp 1049-1061 (2021)
Abstract Liver microphysiological systems (MPSs) are promising models for predicting hepatic drug effects. Yet, after a decade since their introduction, MPSs are not routinely used in drug development due to lack of criteria for ensuring reproducibil
Externí odkaz:
https://doaj.org/article/4e035e2bdd70479abbd93eb9dd228abf
Publikováno v:
BioTechniques, Vol 60, Iss 3, Pp 129-135 (2016)
Single-cell genomics (SCG) is a recently developed tool to study the genomes of unculturable bacterial species. SCG relies on multiple-strand displacement amplification (MDA), PCR, and next-generation sequencing (NGS); however, obtaining sufficient a
Externí odkaz:
https://doaj.org/article/a27eef319eab4d7cb7ac685634015ed5
Autor:
Momchilo Vuyisich, Ayesha Arefin, Karen Davenport, Shihai Feng, Cheryl Gleasner, Kim McMurry, Beverly Parson-Quintana, Jennifer Price, Matthew Scholz, Patrick Chain
Publikováno v:
International Journal of Genomics, Vol 2014 (2014)
Sequencing bacterial genomes has traditionally required large amounts of genomic DNA (~1 μg). There have been few studies to determine the effects of the input DNA amount or library preparation method on the quality of sequencing data. Several new c
Externí odkaz:
https://doaj.org/article/27011e63fe2c41258048ee7065fe3392
Autor:
Qiang Shi, Ayesha Arefin, Lijun Ren, Katy S. Papineau, Dustyn A. Barnette, Laura K. Schnackenberg, Jessica J. Hawes, Mark Avigan, Donna L. Mendrick, Lorna Ewart, Janey Ronxhi
Publikováno v:
Current Protocols. 2
Drug-induced liver injury (DILI) is a significant public health issue, but standard animal tests and clinical trials sometimes fail to predict DILI due to species differences and the relatively low number of human subjects involved in preapproval stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0c0a51ff2756fa95365d16e17d4e16
https://doi.org/10.1002/cpz1.478
https://doi.org/10.1002/cpz1.478
Autor:
Tomasz Kostrzewski, Ayesha Arefin, Alina Miedzik, Donna A. Volpe, David G. Strauss, Amruta Indapurkar, Andres Rubiano, Ryosuke Yokosawa, Murali K. Matta, Neil R. Hartman, Keri Dame, Chloe M. Moulin, David Hughes, Barry A. Rosenzweig, Alexandre J.S. Ribeiro
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 3, Pp 1049-1061 (2021)
Clinical and Translational Science
Clinical and Translational Science
Liver microphysiological systems (MPSs) are promising models for predicting hepatic drug effects. Yet, after a decade since their introduction, MPSs are not routinely used in drug development due to lack of criteria for ensuring reproducibility of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd91d06eec7e7497783382e4e2f119a7
https://doaj.org/article/4e035e2bdd70479abbd93eb9dd228abf
https://doaj.org/article/4e035e2bdd70479abbd93eb9dd228abf
Autor:
R. Martinez, Jen-Huang Huang, Jennifer Foster Harris, Simona Alice Martin, Kiersten Elizabeth Haffey, Q. McCulloch, Rohan Singh, Srinivas Iyer, Ayesha Arefin, Omar Mohammad Ishak, Erin Michelle Higgins, Rashi Iyer, Pulak Nath
Publikováno v:
ACS Biomaterials Science & Engineering. 4:3522-3533
Engineered tissue barrier models offer in vitro alternatives in toxicology and disease research. To mimic barrier-tissue microenvironment, a porous membrane that can approach the stiffness of physiological basement membranes is required. While severa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b9700f0c316f1c8842825eb7c0bd77
https://doi.org/10.1021/acsbiomaterials.8b00578
https://doi.org/10.1021/acsbiomaterials.8b00578
Autor:
Jen-Huang Huang, Jennifer Foster Harris, Kiersten Elizabeth Haffey, Leyla E. Akhadov, Rashi Iyer, Ayesha Arefin, Pulak Nath
Publikováno v:
RSC advances. 8(38)
Thin and flexible elastomeric membranes are frequently used in many microfluidic applications including microfluidic valves and organs-on-a-chip. The elastic properties of these membranes play an important role in the design of such microfluidic devi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b981c019d8e7dbcb3ee46fca66ec30fc
https://pubmed.ncbi.nlm.nih.gov/35539930
https://pubmed.ncbi.nlm.nih.gov/35539930
Autor:
Jen-Huang Huang, Jennifer Foster Harris, Ayesha Arefin, Pulak Nath, Hypes Vd, Rashi Iyer, Platts D
Publikováno v:
Biomedical microdevices. 19(4)
Thin and flexible polymeric membranes play a critical role in tissue engineering applications for example organs-on-a-chip. These flexible membranes can enable mechanical stretch of the engineered tissue to mimic organ-specific biophysical features,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4b1689d7674af9da7d48c3e88fb634
https://pubmed.ncbi.nlm.nih.gov/29116412
https://pubmed.ncbi.nlm.nih.gov/29116412
Autor:
Karen W. Davenport, B. Parson-Quintana, Cheryl D. Gleasner, Matthew B. Scholz, Patrick S. G. Chain, Shihai Feng, Kim McMurry, Jennifer Price, Momchilo Vuyisich, Ayesha Arefin
Publikováno v:
International Journal of Genomics
International Journal of Genomics, Vol 2014 (2014)
International Journal of Genomics, Vol 2014 (2014)
Sequencing bacterial genomes has traditionally required large amounts of genomic DNA (~1 μg). There have been few studies to determine the effects of the input DNA amount or library preparation method on the quality of sequencing data. Several new c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898e49ce9a5ad0463c4cb278360f201a
https://doi.org/10.1155/2014/434575
https://doi.org/10.1155/2014/434575