Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ayelet Lenz"'
Autor:
Diana Esparza, Carinna Lima, Sarah Abuelreich, Ima Ghaeli, Jinhee Hwang, Eunjin Oh, Ayelet Lenz, Angel Gu, Nan Jiang, Fouad Kandeel, Debbie C. Thurmond, Tijana Jovanovic-Talisman
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionDouble C2-like domain beta (DOC2B) is a vesicle priming protein critical for glucose-stimulated insulin secretion in β-cells. Individuals with type 1 diabetes (T1D) have lower levels of DOC2B in their residual functional β-cell mass and
Externí odkaz:
https://doaj.org/article/49be9d7536124d169961b687cb510217
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221456 (2019)
Gastrin is a peptide hormone, which in combination with other factors such as TGFα, EGF or GLP-1, is capable of increasing beta cell mass and lowering blood glucose levels in adult diabetic mice. In humans, administration of a bolus of gastrin alone
Externí odkaz:
https://doaj.org/article/10def19254c942c0a16090f99949c62a
Autor:
Gili Nathan, Sharon Kredo-Russo, Tamar Geiger, Ayelet Lenz, Haggai Kaspi, Eran Hornstein, Shimon Efrat
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122108 (2015)
In-vitro expansion of β cells from adult human pancreatic islets could provide abundant cells for cell replacement therapy of diabetes. However, proliferation of β-cell-derived (BCD) cells is associated with dedifferentiation. Here we analyzed chan
Externí odkaz:
https://doaj.org/article/fd6c2cf200ed4acf808393390972f27d
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112914 (2014)
In vitro expansion of adult human islet β cells is an attractive solution for the shortage of tissue for cell replacement therapy of type 1 diabetes. Using a lineage tracing approach we have demonstrated that β-cell-derived (BCD) cells rapidly dedi
Externí odkaz:
https://doaj.org/article/2481a3b7c0b34e3385a046574e4a0a09
Autor:
Holger A Russ, Elad Sintov, Leeat Anker-Kitai, Orr Friedman, Ayelet Lenz, Ginat Toren, Chen Farhy, Metsada Pasmanik-Chor, Varda Oron-Karni, Philippe Ravassard, Shimon Efrat
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25566 (2011)
Expansion of beta cells from the limited number of adult human islet donors is an attractive prospect for increasing cell availability for cell therapy of diabetes. However, attempts at expanding human islet cells in tissue culture result in loss of
Externí odkaz:
https://doaj.org/article/095836500806439793422aece474e0a8
Autor:
Ayelet Lenz, Jeffrey Rawson, Mohamed I. Husseiny, Fouad Kandeel, Kevin Ferreri, Weiting Du, Jacques C. Mbongue
Publikováno v:
Vaccine. 36(52)
We previously reported the development of an oral vaccine for diabetes based on live attenuated Salmonella-expressing preproinsulin (PPI) as the autoantigen. When combined with host cell-expressed TGFβ, the vaccine prevented the onset of diabetes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c5d70aa315be2ad14bf92b6a1e7995
https://pubmed.ncbi.nlm.nih.gov/30416020
https://pubmed.ncbi.nlm.nih.gov/30416020
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221456 (2019)
PLoS ONE
PLoS ONE
Gastrin is a peptide hormone, which in combination with other factors such as TGFα, EGF or GLP-1, is capable of increasing beta cell mass and lowering blood glucose levels in adult diabetic mice. In humans, administration of a bolus of gastrin alone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3bc5b4eb6663c3da49dc38f5799024
https://doi.org/10.1371/journal.pone.0221456
https://doi.org/10.1371/journal.pone.0221456
Autor:
Philippe Ravassard, Varda Oron-Karni, Holger A. Russ, Leeat Anker-Kitai, Orr Friedman, Metsada Pasmanik-Chor, Ginat Toren, Chen Farhy, Shimon Efrat, Ayelet Lenz, Elad Sintov
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25566 (2011)
PLoS ONE
PLoS ONE
Background Expansion of beta cells from the limited number of adult human islet donors is an attractive prospect for increasing cell availability for cell therapy of diabetes. However, attempts at expanding human islet cells in tissue culture result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718e2c317c84af3669745fd2f77ba6a0
http://europepmc.org/articles/PMC3184150?pdf=render
http://europepmc.org/articles/PMC3184150?pdf=render
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112914 (2014)
PLoS ONE
PLoS ONE
In vitro expansion of adult human islet β cells is an attractive solution for the shortage of tissue for cell replacement therapy of type 1 diabetes. Using a lineage tracing approach we have demonstrated that β-cell-derived (BCD) cells rapidly dedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f791f18fdf34042155d6324efeb74d5f
https://doi.org/10.1371/journal.pone.0112914
https://doi.org/10.1371/journal.pone.0112914