Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ayelet Alpert"'
Autor:
Amit Frishberg, Neta Milman, Ayelet Alpert, Hannah Spitzer, Ben Asani, Johannes B. Schiefelbein, Evgeny Bakin, Karen Regev-Berman, Siegfried G. Priglinger, Joachim L. Schultze, Fabian J. Theis, Shai S. Shen-Orr
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Diseases change over time, both phenotypically and in their underlying molecular processes. Though understanding disease progression dynamics is critical for diagnostics and treatment, capturing these dynamics is difficult due to their compl
Externí odkaz:
https://doaj.org/article/bd7fa885149a45ffa2a623393e803d3b
Autor:
M Abu-Arisha, H Bar-Yosef, Ayelet Alpert, Yehuda Chowers lab Shai Shen-Orr lab Israel, Shiran Gerassy-Vainberg, Yehuda Chowers, T Shvedov, Elina Starosvetsky, Shai S. Shen-Orr, N Maimon
Publikováno v:
Journal of Crohn's and Colitis. 14:S031-S034
Background Anatomical location and extent of disease are main factors that affect inflammatory bowel disease (IBD) course and prognosis. No explanation is available for segmental intestinal involvement in either Crohn’s disease (CD) or ulcerative c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99afe58ee422db8fb74b183ce64cd3c7
https://doi.org/10.1093/ecco-jcc/jjz203.032
https://doi.org/10.1093/ecco-jcc/jjz203.032
Autor:
Amit Frishberg, Neta Milman, Ayelet Alpert, Hannah Spitzer, Ben Asani, Johannes B. Schiefelbein, Siegfried G. Priglinger, Joachim L. Schultze, Fabian J. Theis, Shai S. Shen-Orr
Diseases change over time, both phenotypically and in underlying driving molecular processes. Though understanding disease progression dynamics is critical for diagnostics and treatment, capturing these dynamics is difficult, due to their complexity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7587d1c9ab288be7b3dd6450e39e7765
https://doi.org/10.1101/2021.11.17.468952
https://doi.org/10.1101/2021.11.17.468952
Autor:
Vladimir Jojic, Ayelet Alpert, Cornelia L. Dekker, Daniela Monti, Yingxiang Huang, Tatiana Kuznetsova, Shai S. Shen-Orr, Lu Cui, Francois Haddad, Rita Ostan, Zuzana Krejciova-Rajaniemi, Benoit Lehallier, Tianxiang Gao, Joseph C. Wu, Nazish Sayed, Trevor Hastie, Anissa P. Grawe, Holden T. Maecker, Tony Wyss-Coray, Robert Tibshirani, Khiem Van Nguyen, Jose G. Montoya, Yael Rosenberg-Hasson, Mark M. Davis, David Furman, Claudio Franceschi
Publikováno v:
Nat Aging
While many diseases of aging have been linked to the immunological system, immune metrics capable of identifying the most at-risk individuals are lacking. From the blood immunome of 1,001 individuals aged 8–96 years, we developed a deep-learning me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca81ce150e5419909993a3178646aa5d
https://lirias.kuleuven.be/handle/20.500.12942/686343
https://lirias.kuleuven.be/handle/20.500.12942/686343
Autor:
Renaud Gaujoux, Yuri Gorelik, Katz A, Haggai Bar-Yoseph, N Maimon, Ayelet Alpert, Sigal Pressman, Perets B, Alexandra Blatt, Elina Starosvetsky, Tania Dubovik, Shai S. Shen-Orr, Neta Milman, Shiran Gerassy-Vainberg, Yehuda Chowers
Personalized treatment of complex diseases has been mostly predicated on biomarker identification of one drug-disease combination at a time. Here, we used a novel computational approach termed Disruption Networks to generate a new data type, contextu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f933a02148158160f92ebd7efdf7ca95
https://doi.org/10.1101/2021.06.16.448558
https://doi.org/10.1101/2021.06.16.448558
Autor:
Renaud Gaujoux, Purvesh Khatri, Ayelet Alpert, Steven Schaffert, Xuhuai Ji, Mark M. Davis, Holden T. Maecker, Uri Rosenschein, David Furman, Oren Caspi, Yishai Pickman, Yael Rosenberg-Hasson, Elina Starosvetsky, Ksenya Kveler, Shai S. Shen-Orr, Michael D. Leipold, Hadas Rabani, Cornelia L. Dekker
Publikováno v:
Nature Medicine. 25:487-495
Immune responses generally decline with age. However, the dynamics of this process at the individual level have not been characterized, hindering quantification of an individual’s immune age. Here, we use multiple ‘omics’ technologies to captur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc9815a5a5de6fa68e03471ae71feeb
https://doi.org/10.1038/s41591-019-0381-y
https://doi.org/10.1038/s41591-019-0381-y
Autor:
Doron, Rimar, Abid, Awisat, Lisa, Kaly, Gleb, Slobodin, Itzhak, Rosner, Michael, Rozenbaum, Shira, Ginsberg, Elina, Starosvetsky, Ayelet, Alpert, Shai, Shen-Orr
Publikováno v:
Annals of the rheumatic diseases. 81(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c2d999854e4977c2132842630f3f1e3
https://pubmed.ncbi.nlm.nih.gov/32907804
https://pubmed.ncbi.nlm.nih.gov/32907804
Autor:
Yishai Ofran, Michal Hayun, Ayelet Alpert, Tyler J. Curiel, Elina Starosvetsky, Shai S. Shen-Orr, Ornit Nahman
Publikováno v:
Cell Syst
Single-cell technologies allow characterization of cancer samples as continuous developmental trajectories. Yet, the obtained temporal resolution cannot be leveraged for a comparative analysis due to the large phenotypic heterogeneity existing betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e746d907b84314f0f5fcb289bd1c8fda
https://pubmed.ncbi.nlm.nih.gov/34624253
https://pubmed.ncbi.nlm.nih.gov/34624253
Autor:
Caspar, Mewes, Benedikt, Büttner, José, Hinz, Ayelet, Alpert, Aron Frederik, Popov, Michael, Ghadimi, Tim, Beissbarth, Mladen, Tzvetkov, Shai, Shen-Orr, Ingo, Bergmann, Ashham, Mansur
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a surface protein on T cells, that has an inhibitory effect on the host immune reaction and prevents overreaction of the immune system. Because the functional single-nucleotide polymorphism (SNP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::406591c55a2dbae069827738240bf8f0
http://link.springer.com/article/10.1038/s41598-018-33246-9
http://link.springer.com/article/10.1038/s41598-018-33246-9
Autor:
Joseph C. Wu, Tony Wyss-Coray, Robert Tibshirani, Cornelia L. Dekker, Holden T. Maecker, Daniela Monti, Jose G. Montoya, Tatiana Kuznetsova, Shai S. Shen-Orr, Trevor Hastie, Lu Cui, Anissa P. Grawe, Rita Ostan, Francois Haddad, Yingxiang Huang, Benoit Lehallier, Nazish Sayed, Vladimir Jojic, Yael Rosenberg-Hasson, Mark M. Davis, David Furman, Claudio Franceschi, Zuzana Krejciova-Rajaniemi, Ayelet Alpert, Tianxiang Gao, Khiem Van Nguyen
Publikováno v:
Nature Aging. 1:748-748
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f5a3a14df469bef611cef03eac0d258
https://doi.org/10.1038/s43587-021-00102-x
https://doi.org/10.1038/s43587-021-00102-x