Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Ayele H. Negussie"'
Autor:
Joshua Owen, Ayele H. Negussie, Scott R. Burks, Jose Delgado, Andrew S. Mikhail, Jocelyne Rivera, William F. Pritchard, John W. Karanian, Eleanor Stride, Joseph A. Frank, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Transarterial chemoembolization (TACE) is an image-guided minimally invasive treatment for liver cancer which involves delivery of chemotherapy and embolic material into tumor-supplying arteries to block blood flow to a liver tumor and to de
Externí odkaz:
https://doaj.org/article/c9a49119fd1745cfbd2e2feef1e8a23f
Autor:
Ayele H. Negussie, Robert Morhard, Jocelyne Rivera, Jose F. Delgado, Sheng Xu, Bradford J. Wood
Publikováno v:
Functional Composite Materials, Vol 5, Iss 1, Pp 1-23 (2024)
Abstract Heat-based local ablation techniques are effective treatments for specific oligometastatic and localized cancers and are being studied for their potential to induce immunogenic cell death and augment systemic immune responses to immunotherap
Externí odkaz:
https://doaj.org/article/cb962dc0d0c54cd797025d66603912fe
Autor:
Ayele H. Negussie, Andrew S. Mikhail, Joshua W. Owen, Natalie Hong, Camella J. Carlson, Yiqing Tang, Kendal Paige Carrow, Michal Mauda-Havakuk, Andrew L. Lewis, John W. Karanian, William F. Pritchard, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Hepatocellular carcinoma (HCC) is an aggressive liver cancer with limited effective treatment options. In this study, we selected TLR agonists imiquimod (IMQ), gardiquimod (GARD), GS-9620 and DSR 6434, and a small molecule checkpoint inhibit
Externí odkaz:
https://doaj.org/article/a5f7912257d54f5cb2ffe67f7c41928a
Autor:
Ayele H. Negussie, Andrew S. Mikhail, Joshua W. Owen, Natalie Hong, Camella J. Carlson, Yiqing Tang, Kendal Paige Carrow, Michal Mauda-Havakuk, Andrew L. Lewis, John W. Karanian, William F. Pritchard, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/21cccb8cdbf44c99b3ea9c43414d7873
Autor:
Ayele H. Negussie, Quirina M. B. de Ruiter, Hugh Britton, Danielle R. Donahue, Quentin Boffi, Young-Seung Kim, William F. Pritchard, Chrit Moonen, Gert Storm, Andrew L. Lewis, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Current therapy for hypervascular cancers, e.g., hepatocellular carcinoma, includes occlusion of the tumor blood supply by arterial infusion of embolic microspheres (beads) suspended in iodine-based contrast under fluoroscopic guidance. Avai
Externí odkaz:
https://doaj.org/article/5c8343e6e7924265820253b48addecee
Autor:
Anjan Motamarry, Ayele H. Negussie, Christian Rossmann, James Small, A. Marissa Wolfe, Bradford J. Wood, Dieter Haemmerich
Publikováno v:
International Journal of Hyperthermia, Vol 36, Iss 1, Pp 816-825 (2019)
Objective: Thermosensitive liposomal doxorubicin (TSL–Dox) is a promising stimuli-responsive nanoparticle drug delivery system that rapidly releases the contained drug in response to hyperthermia (HT) (>40 °C). Combined with localized heating, TSL
Externí odkaz:
https://doaj.org/article/b93222ca05f94f0298ec0be2af4c7cde
Autor:
Avinash Eranki, Andrew S. Mikhail, Ayele H. Negussie, Prateek S. Katti, Bradford J. Wood, Ari Partanen
Publikováno v:
International Journal of Hyperthermia, Vol 36, Iss 1, Pp 517-528 (2019)
Purpose: Tissue-mimicking phantoms (TMPs) are synthetic materials designed to replicate properties of biological tissues. There is a need to quantify temperature changes following ultrasound or magnetic resonance imaging-guided high intensity focused
Externí odkaz:
https://doaj.org/article/63d003285b724317815bb42ae21875f8
Autor:
Gert Blueschke, MD, Alina Boico, MSc, Ayele H. Negussie, PhD, Pavel Yarmolenko, PhD, Bradford J. Wood, PhD, Ivan Spasojevic, PhD, Ping Fan, MS, Detlev Erdmann, MD, PhD, MHS, Thies Schroeder, PhD, Michael Sauerbier, MD, PhD, Bruce Klitzman, PhD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 6, Iss 7, p e1739 (2018)
Background:. Enhancing drug delivery to the skin has importance in many therapeutic strategies. In particular, the outcome in vascularized composite allotransplantation mainly depends on systemic immunosuppression to prevent and treat episodes of tra
Externí odkaz:
https://doaj.org/article/c228dbfa32274986b73599d2fee6a3d8
Autor:
Reza Seifabadi, Ming Li, Sheng Xu, Yue Chen, Alex Squires, Ayele H. Negussie, Ivane Bakhutashvili, Peter Choyke, Ismail B. Turkbey, Zion Tsz Ho Tse, Bradford J. Wood
Publikováno v:
Journal of Imaging, Vol 4, Iss 12, p 140 (2018)
Purpose: A novel grid-template-mimicking MR-compatible robot was developed for in-gantry MRI-guided focal laser ablation of prostate cancer. Method: A substantially compact robot was designed and prototyped to meet in-gantry lithotomy ergonomics and
Externí odkaz:
https://doaj.org/article/12f7c2f76f8e4159add312462296cbf2
Autor:
Andrew S. Mikhail, William F. Pritchard, Ayele H. Negussie, Gazi Inkiyad, Dilara J. Long, Michal Mauda-Havakuk, Paul G. Wakim, William van der Sterren, Elliot B. Levy, Andrew L. Lewis, John W. Karanian, Bradford J. Wood
Publikováno v:
Investigative radiology. 57(8)
The aims of this study were to develop a model to estimate drug dose delivered to tumors after transarterial chemoembolization (TACE) with radiopaque drug-eluting beads (DEBs) based on DEB density on cone-beam computed tomography (CT) and to evaluate