Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Aydin Tozeren"'
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201751 (2018)
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death in the US. Despite multiple large-scale genetic sequencing studies, identification of predictors of patient survival remains challenging. We performed a comprehensive
Externí odkaz:
https://doaj.org/article/f1b35280741f45089a4114145c8752dc
Publikováno v:
Cancer Informatics, Vol 2015, Iss 14, Pp 113-119 (2015)
Externí odkaz:
https://doaj.org/article/80a271e9942e4870b5403c7cb66fbf78
Publikováno v:
Cancer Informatics, Vol 14 (2015)
Ovarian cancer (OC) is a leading cause of cancer mortality, but aside from a few well-studied mutations, very little is known about its underlying causes. As such, we performed survival analysis on ovarian copy number amplifications and gene expressi
Externí odkaz:
https://doaj.org/article/5375b8500111429cad6221c77d520b79
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33174 (2012)
Pandemic and seasonal respiratory viruses are a major global health concern. Given the genetic diversity of respiratory viruses and the emergence of drug resistant strains, the targeted disruption of human host-virus interactions is a potential thera
Externí odkaz:
https://doaj.org/article/e235be63a9d34f569855921560d0b4f0
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20735 (2011)
Virus proteins alter protein pathways of the host toward the synthesis of viral particles by breaking and making edges via binding to host proteins. In this study, we developed a computational approach to predict viral sequence hotspots for binding t
Externí odkaz:
https://doaj.org/article/01a04dd9e44a467aa8bddcffc1edd4cf
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23293 (2011)
HIV proteins target host hub proteins for transient binding interactions. The presence of viral proteins in the infected cell results in out-competition of host proteins in their interaction with hub proteins, drastically affecting cell physiology. F
Externí odkaz:
https://doaj.org/article/2a97783694a8451ea6ed2b2e36588f03
Autor:
Yichuan Liu, Aydin Tozeren
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12890 (2010)
Single nucleotide polymorphisms (SNPs) constitute an important mode of genetic variations observed in the human genome. A small fraction of SNPs, about four thousand out of the ten million, has been associated with genetic disorders and complex disea
Externí odkaz:
https://doaj.org/article/0bd048d52cb94e90851e1a194a335be7
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8942 (2010)
Over the course of HIV infection, virus replication is facilitated by the phosphorylation of HIV proteins by human ERK1 and ERK2 mitogen-activated protein kinases (MAPKs). MAPKs are known to phosphorylate their substrates by first binding with them a
Externí odkaz:
https://doaj.org/article/118898fbad874f95b95b7bbde7b1db96
Autor:
Richard G. Pestell, Steven B. McMahon, Chenguang Wang, Michael Gormley, Sankar Addya, Ceylan Tanes, Aydin Tozeren, Michael P. Lisanti, Andrew Quong, Hallgeir Rui, Zhiping Li, Adam Ertel, Jing Wang, Jie Zhou, Wei Zhang, Shaoxin Cai, Kongming Wu, Ke Chen
PDF file - 293K, Supplemental Figure 1. Reduced DACH1 mRNA in NSCLC. Supplemental Figure 2. DACH1 and p53 co-localized in a nuclear extranucleolar location.Supplemental Figure 3. Western blot analysis of H1299 cells treated with 5-Aza-2'- deoxycytidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489c3c5a41d3cbf97699431aaab2ea3f
https://doi.org/10.1158/0008-5472.22396085
https://doi.org/10.1158/0008-5472.22396085
Autor:
Richard G. Pestell, Steven B. McMahon, Chenguang Wang, Michael Gormley, Sankar Addya, Ceylan Tanes, Aydin Tozeren, Michael P. Lisanti, Andrew Quong, Hallgeir Rui, Zhiping Li, Adam Ertel, Jing Wang, Jie Zhou, Wei Zhang, Shaoxin Cai, Kongming Wu, Ke Chen
PDF file - 72K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d82e6b2785a0b9074b2f01eb83dbab
https://doi.org/10.1158/0008-5472.22396088
https://doi.org/10.1158/0008-5472.22396088