Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ayca Seyhan Agircan"'
Autor:
Leen J M Seys, Fien M Verhamme, Lisa L Dupont, Elke Desauter, Julia Duerr, Ayca Seyhan Agircan, Griet Conickx, Guy F Joos, Guy G Brusselle, Marcus A Mall, Ken R Bracke
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129897 (2015)
Airway surface dehydration, caused by an imbalance between secretion and absorption of ions and fluid across the epithelium and/or increased epithelial mucin secretion, impairs mucociliary clearance. Recent evidence suggests that this mechanism may b
Externí odkaz:
https://doaj.org/article/f500d0f6563d431289fad7355f5ca904
Autor:
Julia Duerr, Dominik H. W. Leitz, Magdalena Szczygiel, Dmytro Dvornikov, Simon G. Fraumann, Clemens Kreutz, Piotr K. Zadora, Ayça Seyhan Agircan, Philip Konietzke, Theresa A. Engelmann, Jan Hegermann, Surafel Mulugeta, Hiroshi Kawabe, Lars Knudsen, Matthias Ochs, Daniela Rotin, Thomas Muley, Michael Kreuter, Felix J. F. Herth, Mark O. Wielpütz, Michael F. Beers, Ursula Klingmüller, Marcus A. Mall
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Idiopathic pulmonary fibrosis (IPF) is a devastating disease with poor prognosis. Here, the authors show that deficiency of the E3 ubiqutin-protein ligase Nedd4-2 in airway epithelial cells causes IPF-like disease in adult mice. This model may aid st
Externí odkaz:
https://doaj.org/article/ae55c88d44b14c0496555b2c7a52b8da