Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ayaz Shahid"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/171fac00c2d74d75839ab8553a4ddf18
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/b8d7b8b3d3c742bf8c135626273ba80d
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 563 (2024)
Cancer remains a significant global health concern, with lung cancer consistently leading as one of the most common malignancies. Genetic aberrations involving receptor tyrosine kinases (RTKs) are known to be associated with cancer initiation and dev
Externí odkaz:
https://doaj.org/article/4ae80f5e68914461b9c3377a187b1e14
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Ganoderma lucidum (GL), commonly known as “Lingzhi”, is a well-known medicinal mushroom with antioxidant and anti-cancer activity. This study examined the effects of a commercial GL product (GLSF) containing the spore and fruiting body in a 30:8
Externí odkaz:
https://doaj.org/article/fe78b34b4ddd44e2ac8eadc2db4da30e
Autor:
Ruby Tow, Samuel Hanoun, Bradley Andresen, Ayaz Shahid, Jeffrey Wang, Kristen M. Kelly, Frank L. Meyskens, Ying Huang
Publikováno v:
Cancers, Vol 15, Iss 15, p 3819 (2023)
Neoplasm arising from the keratinocytes or melanocytes in the skin is the most prevalent type of cancer in the United States and worldwide. Since ultraviolet (UV) radiation may be a causing factor for several types of skin cancer, effective strategie
Externí odkaz:
https://doaj.org/article/626946f48b61481e8ac58d79974080e8
Autor:
Md Abdullah Shamim, Ayaz Shahid, Pabitra K. Sardar, Steven Yeung, Jeremiah Reyes, Jenny Kim, Cyrus Parsa, Robert Orlando, Jeffrey Wang, Kristen M. Kelly, Frank L. Meyskens, Bradley T. Andresen, Ying Huang
Publikováno v:
Nanomaterials, Vol 13, Iss 5, p 929 (2023)
The R-carvedilol enantiomer, present in the racemic mixture of the chiral drug carvedilol, does not bind to the β-adrenergic receptors, but exhibits skin cancer preventive activity. For skin delivery, R-carvedilol-loaded transfersomes were prepared
Externí odkaz:
https://doaj.org/article/3d025cf03a8f49b5987bc6fd3a863216
Autor:
Ayaz Shahid, Mengbing Chen, Carol Lin, Bradley T. Andresen, Cyrus Parsa, Robert Orlando, Ying Huang
Publikováno v:
Cancers, Vol 15, Iss 3, p 583 (2023)
The current study evaluated the effects of the β-blocker carvedilol on benzo(a)pyrene (B(a)P) and its active metabolite benzo(a)pyrene diol epoxide (BPDE)-induced lung toxicity, inflammation and carcinogenesis and explored the potential mechanisms.
Externí odkaz:
https://doaj.org/article/855f46154bf04520b2a3f47006c31d92
Autor:
Ayaz Shahid, Matthew Huang, Mandy Liu, Md Abdullah Shamim, Cyrus Parsa, Robert Orlando, Ying Huang
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0265615 (2022)
The medicinal mushroom Ganoderma lucidum is traditionally used for treating multiple diseases, including cancer. This study examined skin cancer preventive activity of a commercial product containing spore and fruiting body in 30:8 ratio (GLSF). Extr
Externí odkaz:
https://doaj.org/article/691429e566e24f83810faf1defe1b7f0
Autor:
Mengbing Chen, Md Abdullah Shamim, Ayaz Shahid, Steven Yeung, Bradley T. Andresen, Jeffrey Wang, Vijaykumar Nekkanti, Frank L. Meyskens, Kristen M. Kelly, Ying Huang
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1151 (2020)
The β-blocker carvedilol has been shown to prevent skin carcinogenesis in vitro and in vivo. Since systemic absorption of the β-blocker may cause cardiovascular disturbance, we developed a carvedilol loaded transfersome for skin-targeted delivery.
Externí odkaz:
https://doaj.org/article/ed49c9635b2845b5ab89447d4593eda0
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 798 (2020)
The β-blocker carvedilol prevents ultraviolet (UV)-induced skin cancer, but the mechanism is unknown. Since carvedilol possesses antioxidant activity, this study investigated whether carvedilol prevents oxidative photodamage of skin, a precursor eve
Externí odkaz:
https://doaj.org/article/5003f0ff19b24e89ac1f822b4b4550ea