Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ayatoshi Andou"'
Autor:
Kayo Ikeda, Makoto Kinoshita, Hisako Kayama, Shushi Nagamori, Pornparn Kongpracha, Eiji Umemoto, Ryu Okumura, Takashi Kurakawa, Mari Murakami, Norihisa Mikami, Yasunori Shintani, Satoko Ueno, Ayatoshi Andou, Morihiro Ito, Hideki Tsumura, Koji Yasutomo, Keiichi Ozono, Seiji Takashima, Shimon Sakaguchi, Yoshikatsu Kanai, Kiyoshi Takeda
Publikováno v:
Cell Reports, Vol 21, Iss 7, Pp 1824-1838 (2017)
Summary: Foxp3+ regulatory T (Treg) cells, which suppress immune responses, are highly proliferative in vivo. However, it remains unclear how the active replication of Treg cells is maintained in vivo. Here, we show that branched-chain amino acids (B
Externí odkaz:
https://doaj.org/article/2f6375032a6040699398008e3fa35d9a
Autor:
Tadakazu Hisamatsu, Susumu Okamoto, Masaki Hashimoto, Takahiko Muramatsu, Ayatoshi Andou, Michihide Uo, Mina T Kitazume, Katsuyoshi Matsuoka, Tomoharu Yajima, Nagamu Inoue, Takanori Kanai, Haruhiko Ogata, Yasushi Iwao, Minoru Yamakado, Ryosei Sakai, Nobukazu Ono, Toshihiko Ando, Manabu Suzuki, Toshifumi Hibi
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e31131 (2012)
BACKGROUND: Inflammatory bowel disease (IBD) is a chronic intestinal disorder that is associated with a limited number of clinical biomarkers. In order to facilitate the diagnosis of IBD and assess its disease activity, we investigated the potential
Externí odkaz:
https://doaj.org/article/2b32881ecfe64294872929c0f1b53339
Publikováno v:
Folia Pharmacologica Japonica. 158:203-210
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7dcb83ef6ffb0abefe9a96f54972d6a
https://doi.org/10.1254/fpj.22120
https://doi.org/10.1254/fpj.22120
Publikováno v:
Gastroenterology. 160:S-325
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d273e30d176e8d442ec5432a95165170
https://doi.org/10.1016/s0016-5085(21)01501-8
https://doi.org/10.1016/s0016-5085(21)01501-8
Autor:
Ryohei Yokoyama, Tomohisa Hatta, Ryusuke Nakagawa, Hayakawa Nobuhiko, Masataka Shoji, Makoto Shiozaki, Manami Shuto, Yoichiro Shima, Kanna Kuribayashi, Hiroyuki Eda, Misato Noguchi, Yukie Seki, Manabu Suzuki, Agung Eviryanti, Shun-ichiro Iemura, Ayatoshi Andou, Hikaru Nishio, Sen Takeshita, Takashi Yamamoto, Masatsugu Noguchi, Kuniya Sakurai, Tohru Natsume, Shunsuke Kageyama, Itsuya Tanabe
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:3021-3029
Interleukin-12 (IL-12) and IL-23 are proinflammatory cytokines and therapeutic targets for inflammatory and autoimmune diseases, including inflammatory bowel diseases, psoriasis, rheumatoid arthritis, and multiple sclerosis. We describe the discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c53b04d20fe65be97c1dad86158452b
https://doi.org/10.1016/j.bmc.2014.03.036
https://doi.org/10.1016/j.bmc.2014.03.036
Autor:
Kiyoshi Takeda, Hisako Kayama, Koji Yasutomo, Makoto Kinoshita, Takashi Kurakawa, Yoshikatsu Kanai, Shimon Sakaguchi, Yasunori Shintani, Seiji Takashima, Shushi Nagamori, Mari Murakami, Ayatoshi Andou, Morihiro Ito, Norihisa Mikami, Ryu Okumura, Pornparn Kongpracha, Eiji Umemoto, Kayo Ikeda, Satoko Ueno, Keiichi Ozono, Hideki Tsumura
Publikováno v:
Cell Reports, Vol 21, Iss 7, Pp 1824-1838 (2017)
Summary: Foxp3+ regulatory T (Treg) cells, which suppress immune responses, are highly proliferative in vivo. However, it remains unclear how the active replication of Treg cells is maintained in vivo. Here, we show that branched-chain amino acids (B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff72f09bf3ea4154963d483527f2ad1
https://pubmed.ncbi.nlm.nih.gov/29141216
https://pubmed.ncbi.nlm.nih.gov/29141216
Publikováno v:
Current Rheumatology Reviews. 5:252-258
Amino acids are not only the building blocks of proteins but are also key regulators of various pathological and physiological processes, including immune responses, in living cells. However, the mechanisms responsible for these effects of amino acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75e3afeb0c5a72e88bce0a3ebea5bace
https://doi.org/10.2174/157339709790192567
https://doi.org/10.2174/157339709790192567
Autor:
Chieko Ejima, Hiroyuki Eda, Ayatoshi Andou, Tomoko Miyazawa, Shunsuke Kageyama, Toshihiko Sugiura, Taeko Dohi, Akira Nakayama
Publikováno v:
Journal of Crohn'scolitis. 7(11)
Background and aims Inhibition of lymphocyte trafficking by treatment with an anti-α4 integrin antibody has been clinically validated as a therapeutic approach for inflammatory bowel disease (IBD), and the orally effective ‘anti-α4 integrin thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afab3658bca5f893f257d28cdf8c296
https://pubmed.ncbi.nlm.nih.gov/23623333
https://pubmed.ncbi.nlm.nih.gov/23623333
Autor:
Akira Nakayama, Taeko Dohi, Toshihiko Sugiura, Chieko Ejima, Hiroyuki Eda, Tomoko Miyazawa, Ayatoshi Andou, Shunsuke Kageyama
Publikováno v:
The Journal of pharmacology and experimental therapeutics.
Inhibition of lymphocyte trafficking by treatment with an antibody to α4 integrin has been clinically validated as a therapeutic approach for inflammatory bowel disease (IBD). The aim of this study was to investigate the pharmacological profile of A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ba6242142e27b32d2c3a6d1ace2e49
https://pubmed.ncbi.nlm.nih.gov/22893217
https://pubmed.ncbi.nlm.nih.gov/22893217
Autor:
Manami Shuto, Takashi Yamamoto, Masatsugu Noguchi, Kuniya Sakurai, Shoji Masataka, Eviryanti Agung, Hiroyuki Eda, Yoichiro Shima, Ryusuke Nakagawa, Ryohei Yokoyama, Yukie Seki, Misato Noguchi, Hikaru Nishio, Ayatoshi Andou, Itsuya Tanabe, Hayakawa Nobuhiko, Sen Takeshita, Shunsuke Kageyama, Makoto Shiozaki
Publikováno v:
Gastroenterology. 142:S-864
A Novel Orally Active Phosphatidylinositol 3-Phosphate 5-Kinase (Pikfyve) Inhibitor Ameliorates Mouse Colitis by Inhibition of IL-12 and IL-23 Production From Macrophages Ayatoshi Andou, Takashi Yamamoto, Eviryanti Agung, Yukie Seki, Hikaru Nishio, M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a211e5b155f94110a8e76126510ecc10
https://doi.org/10.1016/s0016-5085(12)63351-4
https://doi.org/10.1016/s0016-5085(12)63351-4