Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ayat Hija"'
Autor:
Yaron Suissa, Judith Magenheim, Miri Stolovich-Rain, Ayat Hija, Patrick Collombat, Ahmed Mansouri, Lori Sussel, Beatriz Sosa-Pineda, Kyle McCracken, James M Wells, R Scott Heller, Yuval Dor, Benjamin Glaser
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70397 (2013)
Neurogenin3(+) (Ngn3(+)) progenitor cells in the developing pancreas give rise to five endocrine cell types secreting insulin, glucagon, somatostatin, pancreatic polypeptide and ghrelin. Gastrin is a hormone produced primarily by G-cells in the stoma
Externí odkaz:
https://doaj.org/article/7992f71fd29e411aacd667e72efa1204
Autor:
Judith Furth-Lavi, Ayat Hija, Sharona Tornovsky-Babeay, Adi Mazouz, Tehila Dahan, Miri Stolovich-Rain, Agnes Klochendler, Yuval Dor, Dana Avrahami, Benjamin Glaser
Publikováno v:
Cell Reports. 41:111719
Diabetogenic ablation of beta cells in mice triggers a regenerative response whereby surviving beta cells proliferate and euglycemia is regained. Here, we identify and characterize heterogeneity in response to beta cell ablation. Efficient beta cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e7f1325d689e0abcccb1cf9ce41a49
https://doi.org/10.1016/j.celrep.2022.111719
https://doi.org/10.1016/j.celrep.2022.111719
Autor:
Michael Brandeis, Joseph Grimsby, Benjamin Glaser, Ayat Hija, Agnes Klochendler, Seth J. Salpeter, Yuval Dor
Publikováno v:
Diabetes; Vol 63
Diabetes
Diabetes
Most of our knowledge on cell kinetics stems from in vitro studies of continuously dividing cells. In this study, we determine in vivo cell-cycle parameters of pancreatic β-cells, a largely quiescent population, using drugs that mimic or prevent glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49f721f53e284393e80ee4f5d7693f6
Autor:
Benjamin Glaser, Rotem Karni, Yuval Dor, Ayat Hija, Pushkar Malakar, Gil Leibowitz, Lital Chartarifsky
Publikováno v:
Scientific Reports
Type 2 Diabetes (T2DM) affects more than 300 million people worldwide. One of the hallmarks of T2DM is peripheral insulin resistance, in part due to unproductive insulin signaling through the insulin receptor. The insulin receptor (INSR) exists as tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528c49cd8e93c35cb0b07c72c89b63d7
https://doi.org/10.1038/srep31222
https://doi.org/10.1038/srep31222
Publikováno v:
Journal of Biological Chemistry; Vol 287
Journal of Biological Chemistry
Journal of Biological Chemistry
Recent studies suggested that in old mice, beta cells lose their regenerative potential and cannot respond to mitogenic triggers. These studies examined beta cell replication in aged mice under basal conditions and in response to specific stimuli inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b81392064d2eeb1f606a16bcf4cbe6
Autor:
Noa Weinberg-Corem, Miri Stolovich-Rain, Ann Saada, Frances M. Ashcroft, Yuval Dor, Daniela Dadon, Benjamin Glaser, Vered Ben-Hur, Shay Porat, Ayat Hija, Peter White, Zvi Granot, Rotem Karni, Christophe Girard, Joseph Grimsby, Rachel Schyr-Ben-Haroush, Sharona Tornovsky-Babaey, Mark A. Magnuson, Klaus H. Kaestner
Publikováno v:
Cell Metabolism
Cell Metabolism, Elsevier, 2011, 13 (4), pp.440-449. ⟨10.1016/j.cmet.2011.02.012⟩
Cell Metabolism; Vol 13
Cell Metabolism, Elsevier, 2011, 13 (4), pp.440-449. ⟨10.1016/j.cmet.2011.02.012⟩
Cell Metabolism; Vol 13
SummaryRecent studies revealed a surprising regenerative capacity of insulin-producing β cells in mice, suggesting that regenerative therapy for human diabetes could in principle be achieved. Physiologic β cell regeneration under stressed condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af93a46a12bd053f5bc841fb37ec017c
Autor:
Oren Ziv, Judith Magenheim, Roni Werman, Agnes Klochendler, Eyal Mishani, Yuval Dor, Eli Keshet, Ohad Ilovich, Alon Lazarus, Ondine Cleaver, Ayat Hija
Publikováno v:
Development; Vol 138
How organ size and form are controlled during development is a major question in biology. Blood vessels have been shown to be essential for early development of the liver and pancreas, and are fundamental to normal and pathological tissue growth. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a56e62976892d033345c94b07f61ab
Autor:
Daniela Dadon, Ayat Hija, Benjamin Glaser, Kevan C. Herold, Rachel Schyr-Ben Haroush, Miri Stolovich-Rain, Tricia R. Bhatti, Oren Ziv, Tehila Kadosh, Sharona Tornovsky-Babeay, Frances M. Ashcroft, Louis H. Philipson, Peter In 'T Veld, Charles A. Stanley, Zvi Granot, Shay Porat, Elhanan Tzipilevich, Mark A. Magnuson, Yuval Dor, J Furth-Lavi, Ann Saada
Publikováno v:
Cell Metabolism; Vol 19
Summaryβ cell failure in type 2 diabetes (T2D) is associated with hyperglycemia, but the mechanisms are not fully understood. Congenital hyperinsulinism caused by glucokinase mutations (GCK-CHI) is associated with β cell replication and apoptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e39b18635a1f3e5ac624339a0d52c40
https://hdl.handle.net/20.500.14017/72a36fd2-5503-4f1a-b231-a822b5c6fbc3
https://hdl.handle.net/20.500.14017/72a36fd2-5503-4f1a-b231-a822b5c6fbc3
Autor:
Miri Stolovich-Rain, Beatriz Sosa-Pineda, R. Scott Heller, Lori Sussel, Judith Magenheim, Ayat Hija, James M. Wells, Patrick Collombat, Kyle W. McCracken, Yaron Suissa, Yuval Dor, Benjamin Glaser, Ahmed Mansouri
Publikováno v:
PLoS ONE
PLoS One
PLoS ONE, Vol 8, Iss 8, p e70397 (2013)
PLoS ONE, Public Library of Science, 2013, 8 (8), pp.e70397. ⟨10.1371/journal.pone.0070397⟩
PLoS ONE; Vol 8
PLoS One
PLoS ONE, Vol 8, Iss 8, p e70397 (2013)
PLoS ONE, Public Library of Science, 2013, 8 (8), pp.e70397. ⟨10.1371/journal.pone.0070397⟩
PLoS ONE; Vol 8
International audience; Neurogenin3(+) (Ngn3(+)) progenitor cells in the developing pancreas give rise to five endocrine cell types secreting insulin, glucagon, somatostatin, pancreatic polypeptide and ghrelin. Gastrin is a hormone produced primarily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06c6bef5bdbac8be5e5ffb635fc925a
https://pubmed.ncbi.nlm.nih.gov/23940571
https://pubmed.ncbi.nlm.nih.gov/23940571
Autor:
Ayat Hija, Shay Porat, Zvi Granot, Danny Ben-Zvi, Noa Weinberg-Corem, Miri Stolovich-Rain, J Furth-Lavi, Benjamin Glaser, Sharona Tornovsky-Babaey, Daniela Dadon, Yuval Dor, R. Schyr-Ben-Haroush, Oren Ziv
Publikováno v:
Diabetes, Obesity and Metabolism; Vol 14
Recent studies in mice have shown that pancreatic β-cells have a significant potential for regeneration, suggesting that regenerative therapy for diabetes is feasible. Genetic lineage tracing studies indicate that β-cell regeneration is based on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf7a057547fb47b62ec958e9d86e70a
https://pubmed.ncbi.nlm.nih.gov/22928570
https://pubmed.ncbi.nlm.nih.gov/22928570