Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ayat B. Al-Ghafari"'
Publikováno v:
Current Oncology, Vol 30, Iss 9, Pp 8039-8053 (2023)
We assess the contributions of genetic variants for the enzymes involved in capecitabine metabolism to colorectal cancer (CRC) development risk. In this case-control study, DNA samples were collected from 66 patients (King Abdulaziz University Hospit
Externí odkaz:
https://doaj.org/article/fee0c7bfa4a94680b7b873fdd590dcb0
Publikováno v:
Journal of Immunotoxicology, Vol 19, Iss 1, Pp 81-92 (2022)
Cadmium (Cd) is an immunotoxic metal frequently found in the environment. The in vitro study undertaken here evaluated the immunotoxic effects of Cd in isolated human peripheral blood monocytes (hPBM). The results of the studies of exposures to varyi
Externí odkaz:
https://doaj.org/article/aaf777c81bc744d3b100bf9ed6a5a6e0
Autor:
Muhammed A. Bakhrebah PhD, Mohammad Nasrullah MSc, Wesam H. Abdulaal PhD, Mohammed A. Hassan MSc, Halima Siddiqui MSc, Huda A. Al Doghaither PhD, Ulfat M. Omar PhD, Nawal Helmi PhD, Mohannad M. Fallatah PhD, Ayat B. Al-Ghafari PhD, Mohammad Imran Khan PhD, Hani Choudhry PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 19 (2020)
Among all cancer types, colorectal cancer is the third most common in men and the second most common in women globally. Generally, the risk of colorectal cancer increases with age, and colorectal cancer is modulated by various genetic alterations. Al
Externí odkaz:
https://doaj.org/article/e71995730dc24b2aa44aadc98e2c49b5
Autor:
Ayat B. Al-, Ghafari, Halima A. Siddiqui, Hani M. Choudhry, Huda A. Al Doghaither, Huda F. Alshaibi, Hadeil M. Alsufiani, Sawsan A. Rahimulddin
Publikováno v:
Pakistan Journal of Medical and Health Sciences. 16:512-517
Objectives: To assess the relationship between the expression of long non-coding RNAs (lncRNAs), CCAT1, MALAT1, and PANDAR, in CRC patients with varying physical, environmental, and pathophysiological factors. Material and Methods: A case-control stu
Publikováno v:
Journal of Applied Toxicology. 41:1620-1633
Amphotericin B-deoxycholate (Fungizone [FZ]) is a widely used potent antimycotic drug in spite of its nephrotoxic effect via different mechanisms. The effect of FZ on renal cell bioenergetics is not clear. The current study evaluated the effect of FZ
Publikováno v:
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 1, Pp 651-663 (2021)
Saudi Journal of Biological Sciences, Vol 28, Iss 1, Pp 651-663 (2021)
The diabetogenic effects of metals including lead (Pb), mercury (Hg), cadmium (Cd), and molybdenum (Mo) have been reported with poorly identified underlying mechanisms. The current study assessed the effect of metals on the roles of oxidative stress,
Publikováno v:
Saudi Journal of Medicine & Medical Sciences
Background: Polymorphisms in the gene encoding the vitamin D receptor (VDR) affect the protective role of vitamin D against many types of cancers, including colorectal cancer (CRC). Objective: The objective of this study was to assess the effect of f
Autor:
Khalid O. Abulnaja, Huda F. Alshaibi, Hadeil M. Alsufiani, Abdulrahman L. Al-Malki, Said S Moselhy, Taha A. Kumosani, Muqtadir Baig Mirza, Ayat B. Al-Ghafari, Abudukadeer Kuerban, Shareefa A. ALGhamadi, Furkhan Ahmed Mohammed, Fareeduddin Quadri Syed
Publikováno v:
Journal of Food Measurement and Characterization. 14:2155-2162
The elevated blood sugar slowly attacks reactive amino group of functional proteins and impairs its functions, generates reactive oxygen species (ROS) as byproduct and increases risk of cancer. Bioactive peptides might act as protecting agent via tra
Publikováno v:
Pakistan Journal of Biological Sciences. 23:306-312
Publikováno v:
Mol Clin Oncol
Cancer is currently among the leading causes of mortality globally. Colorectal cancer (CRC) ranks second among the most common types of cancer in terms of mortality worldwide. This type of cancer arises from mutations in the colonic and rectal epithe