Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ayat Abdelkader"'
Autor:
Lara Heidrich, Ayat Abdelkader, Jan Ornik, Enrique Castro-Camus, Cornelia M. Keck, Martin Koch
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1786 (2023)
(1) Background: Amorphous drug systems are an intensively studied approach to overcome the insufficient bioavailability of poorly soluble drugs. Here, paper tablets were studied, which were made from cellulose-based paper matrices loaded with norflox
Externí odkaz:
https://doaj.org/article/d587a76f3ae24a87b151170c18bc13a1
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 375 (2023)
(1) Background: Many drugs possess poor bioavailability, and many strategies are available to overcome this issue. In this study, smartFilm technology, i.e., a porous cellulose matrix (paper), in which the active compound can be loaded onto in an amo
Externí odkaz:
https://doaj.org/article/93bfb5e01c2b43c8b4c8d68cc11beef1
Autor:
Ayat Abdelkader, Christoph Moos, Adrien Pelloux, Marcus Pfeiffer, Christian Alter, Stefan Kolling, Cornelia M. Keck
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1188 (2022)
Many orally administrated drugs exhibit poor bioavailability due to their limited solubility. The smartFilm technology is an innovative approach to improve the drug aqueous solubility, where the drug is embedded within the matrix of cellulose-based p
Externí odkaz:
https://doaj.org/article/4e4a82f8066e466b998561a296e4b149
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1918 (2022)
(1) Background: Numerous oral drugs exhibit limited bioavailability due to their poor solubility and poor intestinal permeability. The smartFilm technology is an innovative approach that improves the drug aqueous solubility via incorporating the drug
Externí odkaz:
https://doaj.org/article/362d8e0e2e73408b9c7246a8b6146345
Autor:
Cornelia M. Keck, Ayat Abdelkader, Olga Pelikh, Sabrina Wiemann, Vasudha Kaushik, David Specht, Ralph W. Eckert, Reem M. Alnemari, Henriette Dietrich, Jana Brüßler
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 678 (2022)
(1) Background: The ex vivo porcine ear model is often used for the determination of the dermal penetration efficacy of chemical compounds. This study investigated the influence of the post-slaughter storage time of porcine ears on the dermal penetra
Externí odkaz:
https://doaj.org/article/886f2a684a7c472b91bec5cfe9e8be61
Autor:
Abdallah Mohamed Ayoub, Bernd Gutberlet, Eduard Preis, Ahmed Mohamed Abdelsalam, Alice Abu Dayyih, Ayat Abdelkader, Amir Balash, Jens Schäfer, Udo Bakowsky
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 357 (2022)
Multidrug resistance in pathogenic bacteria has become a significant public health concern. As an alternative therapeutic option, antimicrobial photodynamic therapy (aPDT) can successfully eradicate antibiotic-resistant bacteria with a lower probabil
Externí odkaz:
https://doaj.org/article/43516ba2361841e69e360f7a09c338a3
Autor:
Koch, Lara Heidrich, Ayat Abdelkader, Jan Ornik, Enrique Castro-Camus, Cornelia M. Keck, Martin
Publikováno v:
Pharmaceutics; Volume 15; Issue 7; Pages: 1786
(1) Background: Amorphous drug systems are an intensively studied approach to overcome the insufficient bioavailability of poorly soluble drugs. Here, paper tablets were studied, which were made from cellulose-based paper matrices loaded with norflox
Autor:
Keck, Ayat Abdelkader, Christoph Moos, Adrien Pelloux, Marcus Pfeiffer, Christian Alter, Stefan Kolling, Cornelia M.
Publikováno v:
Pharmaceuticals; Volume 15; Issue 10; Pages: 1188
Many orally administrated drugs exhibit poor bioavailability due to their limited solubility. The smartFilm technology is an innovative approach to improve the drug aqueous solubility, where the drug is embedded within the matrix of cellulose-based p
Autor:
Ayat Abdelkader, Radwa Radwan, Gihan Fetih, Mahmoud El-Badry, Heba A. Fathi, Mahmoud Elsabahy
Publikováno v:
Journal of Pharmaceutical Innovation. 17:572-583
Letrozole (LTZ), an aromatase inhibitor with poor aqueous solubility, is used as the first line treatment for hormonal sensitive breast cancer in postmenopausal women. The purpose of the current study is to develop hyaluronic acid (HA)/chitosan (Cs)-
Publikováno v:
Journal of Pharmacy and Pharmacology. 72:1289-1305
ObjectivesDrug incompatibilities may compromise the safety and effectiveness of combined drugs and result in mild-to-serious clinical complications, such as catheter obstruction, loss of drug efficacy, formation of toxic derivatives and embolism. Var