Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ayari Fuentes-Hernandez"'
Publikováno v:
Mathematical Biosciences and Engineering, Vol 19, Iss 7, Pp 6860-6882 (2022)
Interactions between species are essential in ecosystems, but sometimes competition dominates over mutualism. The transition between mutualism-competition can have several implications and consequences, and it has hardly been studied in experimental
Externí odkaz:
https://doaj.org/article/c27380efa87f43278ce914d7cbdad832
Autor:
Ayari Fuentes-Hernandez, Jessica Plucain, Fabio Gori, Rafael Pena-Miller, Carlos Reding, Gunther Jansen, Hinrich Schulenburg, Ivana Gudelj, Robert Beardmore
Publikováno v:
PLoS Biology, Vol 13, Iss 4, p e1002104 (2015)
We need to find ways of enhancing the potency of existing antibiotics, and, with this in mind, we begin with an unusual question: how low can antibiotic dosages be and yet bacterial clearance still be observed? Seeking to optimise the simultaneous us
Externí odkaz:
https://doaj.org/article/7741a185edc84b788c3451d9ddb55634
Autor:
Rafael Pena-Miller, David Laehnemann, Gunther Jansen, Ayari Fuentes-Hernandez, Philip Rosenstiel, Hinrich Schulenburg, Robert Beardmore
Publikováno v:
PLoS Biology, Vol 11, Iss 4, p e1001540 (2013)
Conventional wisdom holds that the best way to treat infection with antibiotics is to 'hit early and hit hard'. A favoured strategy is to deploy two antibiotics that produce a stronger effect in combination than if either drug were used alone. But ar
Externí odkaz:
https://doaj.org/article/070ccd08a7cd4ce0ba3a11bf439ee3f1
Publikováno v:
PLoS Biology, Vol 8, Iss 9 (2010)
Is a group best off if everyone co-operates? Theory often considers this to be so (e.g. the "conspiracy of doves"), this understanding underpinning social and economic policy. We observe, however, that after competition between "cheat" and "co-operat
Externí odkaz:
https://doaj.org/article/0d58034bcaee4c09a1d15bb195269f00
Autor:
Rafael Peña-Miller, José Carlos Ramón Hernández-Beltrán, Ayari Fuentes-Hernandez, Alvaro San Millan
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology
Frontiers in Microbiology
With plasmid-mediated antibiotic resistance thriving and threatening to become a serious public health problem, it is paramount to increase our understanding of the forces that enable the spread and maintenance of drug resistance genes encoded in mob
Autor:
J. Carlos R. Hernandez-Beltran, Jerónimo Rodríguez-Beltrán, Oscar Bruno Aguilar-Luviano, Jesús Velez-Santiago, Octavio Mondragón-Palomino, R. Craig MacLean, Ayari Fuentes-Hernández, Alvaro San Millán, Rafael Peña-Miller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The rise of antibiotic resistance is a critical public health concern, requiring an understanding of mechanisms that enable bacteria to tolerate antimicrobial agents. Bacteria use diverse strategies, including the amplification of drug-resis
Externí odkaz:
https://doaj.org/article/e03a6d9559a543168547e6a8826f40dc
Autor:
J. Carlos R. Hernandez-Beltran, Javier DelaFuente, Rafael Peña-Miller, Jose Antonio Escudero, Alvaro San Millan, R. Craig MacLean, Ayari Fuentes-Hernandez, Jerónimo Rodríguez-Beltrán
Publikováno v:
Nature ecology & evolution
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Understanding the mechanisms governing innovation is a central element of evolutionary theory. Novel traits usually arise through mutations in existing genes, but trade-offs between new and ancestral protein functions are pervasive and constrain the
Autor:
Anastasia Hernández-Koutoucheva, Raúl Domínguez Palestino, Alán F. Muñoz, Rafael Peña-Miller, Ayari Fuentes-Hernandez
Publikováno v:
J R Soc Interface
The current crisis of antimicrobial resistance in clinically relevant pathogens has highlighted our limited understanding of the ecological and evolutionary forces that drive drug resistance adaptation. For instance, although human tissues are highly
Autor:
Jerónimo Rodríguez-Beltrán, Rafael Peña-Miller, A. San Millán, J.C.R. Hernandez-Beltran, Ayari Fuentes-Hernandez
Publikováno v:
Plasmid. 113:102517
Multicopy plasmids play an important role in bacterial ecology and evolution by accelerating the rate of adaptation and providing a platform for rapid gene amplification and evolutionary rescue. Despite the relevance of plasmids in bacterial evolutio
Autor:
Iván Zea-Armenta, Luis Covarrubias, José-Manuel Baizabal, Niurka Trujillo-Paredes, Dulce-María Arzate, Magdalena Guerra-Crespo, Gilda Guerrero-Flores, Concepción Valencia, Ayari Fuentes-Hernandez
Publikováno v:
Biology Open, Vol 5, Iss 3, Pp 336-347 (2016)
Biology Open
Biology Open
Notch signalling is a well-established pathway that regulates neurogenesis. However, little is known about the role of Notch signalling in specific neuronal differentiation. Using Dll1 null mice, we found that Notch signalling has no function in the