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pro vyhledávání: '"Ayano Okumura"'
Autor:
Kazumi Yoshizawa, Kozue Nakashima, Mizuho Tabuchi, Ayano Okumura, Yuko Nakatake, Mitsuhiko Yamada, Yayoi Tsuneoka, Tatsuya Higashi
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 3, Pp 234-237 (2020)
We investigated whether benzothiazepines could produce anxiolytic effects via allopregnanolone (ALLO) biosynthesis in mice. We compared the behavioral effects caused by benzothiazepines to those caused by carbamazepine and sodium valproate. We found
Externí odkaz:
https://doaj.org/article/bb28e0580f754693a14924a7aea17f7b
Publikováno v:
Synapse (New York, N.Y.). 71(8)
The neurosteroid allopregnanolone (3α, 5α-tetra-hydroprogesterone: ALLO) elicits anxiolytic, anticonvulsant, and hypnotic anesthetic effects in vivo similar to those induced by other positive allosteric modulators of the GABA