Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ayana, Menorca"'
Autor:
Kiel Hards, Chen-Yi Cheung, Natalie Waller, Cara Adolph, Laura Keighley, Zhi Shean Tee, Liam K. Harold, Ayana Menorca, Richard S. Bujaroski, Benjamin J. Buckley, Joel D. A. Tyndall, Matthew B. McNeil, Kyu Y. Rhee, Helen K. Opel-Reading, Kurt Krause, Laura Preiss, Julian D. Langer, Thomas Meier, Erik J. Hasenoehrl, Michael Berney, Michael J. Kelso, Gregory M. Cook
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Derivatives of the FDA-approved drug, amiloride, can eliminate drug-resistant Mycobacterium tuberculosis in vitro by interfering with bacterial energy conservation.
Externí odkaz:
https://doaj.org/article/dae3bf53428948ca8c7fbb2eb80c8d45
Autor:
Scott A. Ferguson, Ayana Menorca, Essie M. Van Zuylen, Chen-Yi Cheung, Michelle A. McConnell, David Rennison, Margaret A. Brimble, Kip Bodle, Scott McDougall, Gregory M. Cook, Adam Heikal
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
In this study we investigated the influence of oxygen availability on a phenotypic microtiter screen to identify new, natural product inhibitors of growth for the bovine mastitis-causing microorganisms; Streptococcus uberis, Staphylococcus aureus, an
Externí odkaz:
https://doaj.org/article/f54776368f7c437aacd82039efa04740
Autor:
Kiel, Hards, Chen-Yi, Cheung, Natalie, Waller, Cara, Adolph, Laura, Keighley, Zhi Shean, Tee, Liam K, Harold, Ayana, Menorca, Richard S, Bujaroski, Benjamin J, Buckley, Joel D A, Tyndall, Matthew B, McNeil, Kyu Y, Rhee, Helen K, Opel-Reading, Kurt, Krause, Laura, Preiss, Julian D, Langer, Thomas, Meier, Erik J, Hasenoehrl, Michael, Berney, Michael J, Kelso, Gregory M, Cook
Publikováno v:
Communications biology. 5(1)
Increasing antimicrobial resistance compels the search for next-generation inhibitors with differing or multiple molecular targets. In this regard, energy conservation in Mycobacterium tuberculosis has been clinically validated as a promising new dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27d4818343c40ab81f2a54807685303c
https://pubmed.ncbi.nlm.nih.gov/35210534
https://pubmed.ncbi.nlm.nih.gov/35210534
Autor:
Kristiana T. Santoso, Bridget L. Stocker, Gregory M. Cook, Mattie S. M. Timmer, Ayana Menorca, Chen-Yi Cheung
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:3532-3545
A library of thirty-two quinolinequinones (QQs) with various amine substituents at the 6- and 7-positions were synthesised efficiently and in good yields for evaluation as potential anti-tuberculosis agents. Mycobacterium tuberculosis growth inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9ab759330e4167f55b63a7c14e433e
https://doi.org/10.1016/j.bmc.2019.06.002
https://doi.org/10.1016/j.bmc.2019.06.002
Autor:
Michelle McConnell, David Rennison, Ayana Menorca, Essie M. Van Zuylen, Scott A. Ferguson, Chen-Yi Cheung, Adam Heikal, Gregory M. Cook, Kip Bodle, Scott McDougall, Margaret A. Brimble
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Frontiers in Microbiology
Frontiers in Microbiology
In this study we investigated the influence of oxygen availability on a phenotypic microtiter screen to identify new, natural product inhibitors of growth for the bovine mastitis-causing microorganisms; Streptococcus uberis, Staphylococcus aureus, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684b6e9a43a69ec743ff86b8fc40401e
https://www.frontiersin.org/article/10.3389/fmicb.2019.01995/full
https://www.frontiersin.org/article/10.3389/fmicb.2019.01995/full
Autor:
Adam Heikal, Bridget L. Stocker, Kiel Hards, Mattie S. M. Timmer, Ayana Menorca, Gregory M. Cook, Chen-Yi Cheung
Publikováno v:
The Journal of antimicrobial chemotherapy. 71(10)
Objectives Quinolinequinones (QQ) have been shown to inhibit the growth of mycobacterial species, but their mode(s) of action and molecular target(s) remain unknown. To facilitate further development of QQ as antimycobacterial drugs, we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff4782d4daa278b98b8937c12004c87
https://pubmed.ncbi.nlm.nih.gov/27365187
https://pubmed.ncbi.nlm.nih.gov/27365187
Autor:
Gregory M. Cook, Kiel Hards, Ayana Menorca, Karima Medini, Paul W. R. Harris, Margaret A. Brimble
Publikováno v:
Chemical Science
Antimicrobial proteins are a rich source of new lead compounds for the development of new drugs that will tackle global resistance towards existing antibiotics.
Antimicrobial proteins are a rich source of new lead compounds for the development o
Antimicrobial proteins are a rich source of new lead compounds for the development o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989597b6674fbe90104153eb4a9072f6
https://pubmed.ncbi.nlm.nih.gov/29899924
https://pubmed.ncbi.nlm.nih.gov/29899924