Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ayala Lampel"'
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract Biomolecular condensates are condensed intracellular phases that are formed by liquid-liquid phase separation (LLPS) of proteins, either in the absence or presence of nucleic acids. These condensed phases regulate various biochemical reactio
Externí odkaz:
https://doaj.org/article/503f54db13814324a8a646f1f94f2980
Autor:
Avigail Baruch Leshem, Sian Sloan-Dennison, Tlalit Massarano, Shavit Ben-David, Duncan Graham, Karen Faulds, Hugo E. Gottlieb, Jordan H. Chill, Ayala Lampel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
The molecular mechanisms underlying the formation of biomolecular condensates have not been fully elucidated. Here the authors show that the LLPS propensity, dynamics, and encapsulation efficiency of designed peptide condensates can be tuned by subtl
Externí odkaz:
https://doaj.org/article/f00422fac195453c853a9e060b8a14fb
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60867 (2013)
Chemical chaperones are small organic molecules which accumulate in a broad range of organisms in various tissues under different stress conditions and assist in the maintenance of a correct proteostasis under denaturating environments. The effect of
Externí odkaz:
https://doaj.org/article/cba61021cc0b4fb3876eb4cf15c7a692
Publikováno v:
ACS Applied Materials & Interfaces. 14:20520-20527
Melanins are natural biopolymers that have remarkable properties including UV-protection, coloration, and antioxidant activity. Their biosynthesis is regulated both spatially and temporally and involves supramolecular templating and compartmentalizat
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 34(47)
Viral factories are intracellular microcompartments formed by mammalian viruses in their host cells, and contain necessary machinery for viral genome replication, capsid assembly, and maturation, thus serving as "factories" for formation of new viral
Autor:
Avigail Baruch Leshem, Sian Sloan-Dennison, Tlalit Massarano, Shavit Ben-David, Duncan Graham, Karen Faulds, Hugo E. Gottlieb, Jordan H. Chill, Ayala Lampel
Inspired by the role of intracellular liquid-liquid phase separation (LLPS) in formation of membraneless organelles, there is great interest in developing dynamic compartments formed by LLPS of intrinsically disordered proteins (IDPs) or short peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e48c3e2c6407fb1add91b05a166508
https://doi.org/10.26434/chemrxiv-2022-013k3
https://doi.org/10.26434/chemrxiv-2022-013k3
Autor:
Duncan Graham, Rein V. Ulijn, Ayala Lampel, Ewen Smith, Sian Sloan-Dennison, Karen Faulds, Eileen Raßlenberg
Publikováno v:
Journal of Raman Spectroscopy. 52:1108-1114
Peptide fibre formation via molecular self-assembly is a key step in a range of cellular processes and increasingly considered as an approach to produce supramolecular biomaterials. We previously demonstrated the self-assembly of the tripeptide lysin
Autor:
Scott A. McPhee, Tlalit Massarano, James M. Aramini, Ye He, Deborah Sementa, Rein V. Ulijn, Ayala Lampel, Salma Kassem
Publikováno v:
Angewandte Chemie International Edition. 60:7564-7569
Melanin and related polyphenolic pigments are versatile functional polymers that serve diverse aesthetic and protective roles across the living world. These polymeric pigments continue to inspire the development of adhesive, photonic, electronic and
Autor:
Ayala Lampel
Publikováno v:
Chem. 6:1222-1236
Summary Supramolecular living matter is remarkably complex in composition and structure and often exists far from equilibrium. The biological manufacturing process involves compartmentalization and confinement, supramolecular templating, and cascades
Autor:
Charalampos G. Pappas, Nadeesha Wijerathne, Jugal Kishore Sahoo, Ankit Jain, Daniela Kroiss, Ivan R. Sasselli, Ana Sofia Pina, Ayala Lampel, Rein V. Ulijn
Publikováno v:
ChemSystemsChem. 4