TGF-β1 induced transdifferentiation of rpe cells is mediated by TAK1.

Autor: Zeev Dvashi, Mordechai Goldberg, Orit Adir, Michal Shapira, Ayala Pollack

Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0122229 (2015)

BACKGROUND AND AIM:Proliferative vitreoretinopathy (PVR) is an active process that develops as a complication upon retinal detachment (RD), accompanied by formation of fibrotic tissue. The main cells involved in the development of fibrotic tissue dur

Externí odkaz: https://doaj.org/article/bca4fcc8c5f54c959450abe77d82a2fd

Reply

Autor: Raj K. Maturi, Ayala Pollack, Harvey S. Uy, Monica Varano, Andre M. V. Gomes, Xiao-Yan Li, Harry Cui, Jean Lou, Yehia Hashad, Scott M. Whitcup

Publikováno v: Retina. 37:e37-e40

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8fca757d90b5691a0d3058dd1b5343b
https://doi.org/10.1097/iae.0000000000001548

Three-Year, Randomized, Sham-Controlled Trial of Dexamethasone Intravitreal Implant in Patients with Diabetic Macular Edema

Autor: David S. Boyer, 1 Young Hee Yoon, MD, PhD, 2 Rubens Belfort, Jr, MD, PhD, 3 Francesco Bandello, 4 Raj K. Maturi, 5 Albert J. Augustin, 6 Xiao Yan Li, 7 Harry Cui, 7 Yehia Hashad, 7 Scott M. Whitcup, MDThe MEAD Study Group Principal Investigators: Suel Abujamra, James Acton, Fareed Ali, Andrew Antoszyk, Albert J. Augustin, Carl C. Awh, Adiel Barak, Karl Ulrich Bartz Schmidt, Caroline R. Baumal, Rubens Belfort, J.r., Muna Bhende, William Z. Bridges, David M. Brown, Trevor Carmichael, Ken Carnevale, Antonio M. Casella, Tom Chang, Daniel Chechik, San Ni Chen, Lawrence P. Chong, Victor Chong, Joel Corwin, Catherine Creuzot Garcher, Alan Cruess, Mark Daniell, Marcos P. de Avila, Haroldo Vieira de Moraes, Robert G. Devenyi, Bernard H. Doft, Mark Donaldson, Richard Dreyer, Dean Eliott, Harry M. Engel, Jan Ernest, Thomas F. Essman, Philip M. Falcone, Sharon Fekrat, Joseph R. Ferencz, Joao L. Ferreira, Joao Figueira, Ivan Fiser, Bradley Foster, Gregory M. Fox, William R. Freeman, S. P. Garg, Mark Gillies, David Glaser, Burton G. Goldstein, Andre M. V. Gomes, John R. Gonder, Lingam Gopal, Petrus Gous, Amod Gupta, Anurag Gupta, Lawrence Halperin, Dennis Han, Seenu M. Hariprasad, Frank G. Holz, Peter Kaiser, Bohdana Kalvodova, Barrett Katz, Randy S. Katz, Dariusz Kecik, Judianne Kellaway, Itamar Klemperer, Baruch Kuppermann, Paolo Lanzetta, Rosangela Lattanzio, Won Ki Lee, John Lehr, Monique Leys, Isaac Loose, Andrew Lotery, Da Wen Lu, Paul McCartney, Ajit B. Majji, Jose A. Martinez, Pascale Massin, Raj K. Maturi, Ugo Menchini, Geeta Menon, Mark Michels, Edoardo Midena, James Miller, Paul Mitchell, Joseph Moisseiev, Lawrence Morse, Rafael Navarro, Janos Nemeth, Henry Newland, Richard Newsom, John Nichols, Juan Orellana, Nicola Orzalesi, Augusto Paranhos, Robert Park, Susanna Park, Maurizio Battaglia Parodi, Peter R. Pavan, James Peace, Don J. Perez Ortiz, Ayala Pollack, Kim Ramaswamy, Ramakrishna Ratnakaram, Giuseppe Ravalico, Jiri Rehak, Kourous Rezaei, Stanislao Rizzo, Francisco J. Rodriguez Alvira, Jean Paul Romanet, Steven Rose, Richard B. Rosen, Luca Rossetti, Jose Maria Ruiz Moreno, SriniVas Sadda, Kenneth Sall, Dirk Sandner, Alvaro Fernandez Vega Sanz, Gil Sartani, Stefanie Schmickler, Steven D. Schwartz, Y. R. Sharma, Shwu Jiuan Sheu, Michael Singer, Sobha Sivaprasad, Gisele Soubrane, Petr Soucek, Eric H. Souied, Giovanni Staurenghi, Jan Studnicka, Marta Suarez Figueroa, Walter Y. Takahashi, Patrick L. Tsai, Lawrence J. Ulanski, Harvey Uy, Monica Varano, Miroslav Veith, Igor Vicha, Francesco Viola, Linda Visser, Dov Weinberger, Glenn L. Wing, Edmund Wong, Tien Wong, Edward Wylegala, Jiong Yan, Young Hee Yoon, Lucy H. Young, Hyeong G. Yu, Ingrid E. Zimmer Galler, TOGNETTO, DANIELE

Publikováno v: Ozurdex MEAD Study Group & Newsom, R B 2014, ' Three-year, randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with diabetic macular edema ', Ophthalmology, vol. 121, no. 10, pp. 1904-1914 . https://doi.org/10.1016/j.ophtha.2014.04.024

Purpose: To evaluate the safety and efficacy of dexamethasone intravitreal implant (Ozurdex, DEX implant) 0.7 and 0.35 mg in the treatment of patients with diabetic macular edema (DME).Design: Two randomized, multicenter, masked, sham-controlled, pha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac6868a174f5dad2c622dd901451a00
https://doi.org/10.1016/j.ophtha.2014.04.024

INTRAOCULAR PRESSURE IN PATIENTS WITH DIABETIC MACULAR EDEMA TREATED WITH DEXAMETHASONE INTRAVITREAL IMPLANT IN THE 3-YEAR MEAD STUDY

Autor: Monica Varano, Scott M. Whitcup, Xiao-yan Li, Yehia Hashad, Harvey S. Uy, André Marcelo Vieira Gomes, Harry Cui, Ayala Pollack, Jean Lou, Raj K. Maturi

Publikováno v: Retina. 36:1143-1152

Purpose:To evaluate the occurrence, management, and clinical significance of increases in intraocular pressure (IOP) in patients with diabetic macular edema treated with dexamethasone intravitreal implant (DEX implant).Methods:Randomized, multicenter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d5918c1cafe801754500457b49020af
https://doi.org/10.1097/iae.0000000000001004

Diabetic macular edema treated with ranibizumab following bevacizumab failure in Israel (DERBI study)

Autor: Ayala Pollack, Michaella Goldstein, Rita Ehrlich, Joel Hanhart, Shiri Shulman, Itay Chowers, Wiessam Abu Ahmad, Rinat Kehat, Yoreh Barak, Russell Pokroy, Orit Vidne, Ori Segal

Publikováno v: European journal of ophthalmology. 29(2)

Purpose: To evaluate the outcome of second-line intravitreal ranibizumab treatment in eyes with diabetic macular edema having persistent edema following initial therapy with intravitreal bevacizumab. Methods: Diabetic macular edema treated with ranib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a49cbf71e081b310248bb3e86bef48b
https://pubmed.ncbi.nlm.nih.gov/29916263