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pro vyhledávání: '"Ayako YAMAKAWA"'
Autor:
Yosuke Ito, Yuhei Chadani, Tatsuya Niwa, Ayako Yamakawa, Kodai Machida, Hiroaki Imataka, Hideki Taguchi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Here the authors find that nascent chains enriched in acidic amino acids destabilize the translating ribosome, eventually leading to stochastic premature termination in eukaryotes as in bacteria. Such risk of premature termination influences the amin
Externí odkaz:
https://doaj.org/article/916d1174a4b24e219937c6f63becb21d
Publikováno v:
Nucleic acids research.
Life depends on proteins, which all exist in nascent states when the growing polypeptide chain is covalently attached to a tRNA within the ribosome. Although the nascent chains; i.e., polypeptidyl-tRNAs (pep-tRNAs), are considered as merely transient
Publikováno v:
Japanese Journal of Benthology. 77:38-39