Výsledky vyhledávání

Alterations of Fas and Fas-Related Molecules in Patients with Silicosis

Autor: Ayako Ueki, Masayasu Kusaka, Yasumitsu Nishimura, Hironobu Katsuyama, Takumi Kishimoto, Yoshie Miura, Takemi Otsuki, Akiko Takata, Fuminori Hyodoh, Masafumi Tomita

Publikováno v: Experimental Biology and Medicine. 231:522-533

Persons with silicosis have not only respiratory disorders but also autoimmune diseases. To clarify the mechanisms involved in the dysregulation of autoimmunity found in patients with silicosis, we have been focusing on Fas and Fas-related molecules

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499a392eacfab7ad3e5eac1aafedbf6d
https://doi.org/10.1177/153537020623100506

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Detection, epitope-mapping and function of anti-Fas autoantibody in patients with silicosis

Autor: Hisashi Arikuni, Hiroaki Ueki, Mieko Shiwa, Ayako Ueki, Fuminori Hyodoh, Masayasu Kusaka, Tamayo Hatayama, Hironobu Katsuyama, Wataru Fujimoto, Akiko Takata-Tomokuni, Takemi Otsuki, Yumika Isozaki

Publikováno v: Immunology. 116:21-29

Dysregulation of apoptosis through the Fas-Fas ligand pathway is associated with the onset of autoimmune disease. Since autoantibodies directed against unknown antigens are present in the sera of these patients, sera samples were examined for the pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685401598e3a766f3207aac884bfaf46
https://doi.org/10.1111/j.1365-2567.2005.02192.x

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Dysregulation of Fas and Related Molecules in Silicosis Patients

Autor: Takemi Otsuki, Hironobu Katsuyama, Fuminori Hyodoh, Akiko Takata-Tomokuni, Yoshie Miura, Ayako Ueki

Publikováno v: Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene). 60:30-37

Silicosis patients not only suffer from respiratory disorders but also from autoimmune diseases. To clarify the mechanisms involved in the occurrence of the dysregulation of autoimmunity found in silicosis patients, we have been focusing on investiga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae952f08c0b3fb0117a74566b603bd6
https://doi.org/10.1265/jjh.60.30

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Secretory Ig a in Saliva and Academic Stress

Autor: Tamayo Hatayama, Akiko Takata, Fuminori Hyodoh, Ayako Ueki, Takemi Otsuki, Satoshi Tsujita, Haruko Sakaguchi, Kanehisa Morimoto

Publikováno v: International Journal of Immunopathology and Pharmacology. 17:45-48

Several reports have proposed that the concentration of secretory immunoglobulin A (S-IgA) in saliva is an indicator of psychological stress. With this in mind, we decided to examine it in 10 second year medical student volunteers at Kawasaki Medical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2099f90f67d5c7acc89880c5b6b0986
https://doi.org/10.1177/03946320040170s208

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Intramolecular epitope spreading among anti-caspase-8 autoantibodies in patients with silicosis, systemic sclerosis and systemic lupus erythematosus, as well as in healthy individuals

Autor: Tamayo Hatayama, M Shiwa, A Tomokuni, Masayasu Kusaka, Yumika Isozaki, Kanehisa Morimoto, Tatsuya Takeshita, H Arikuni, Hiroaki Ueki, Ayako Ueki

Publikováno v: Clinical and Experimental Immunology. 129:556-561

SUMMARY Dysregulation of apoptosis through the Fas-Fas ligand pathway is relevant in autoimmune disease onset. We recently reported elevated serum levels of sFas in patients with silicosis, systemic sclerosis (SSC) and systemic lupus erythematosus (S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2191c88a355cd321483680ab1da060
https://doi.org/10.1046/j.1365-2249.2002.01939.x

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Interleukin 10 abolishes the growth inhibitory effects of all-trans retinoic acid on human myeloma cells

Autor: Sakura Eda, Yoshinobu Matsuo, Yoshihito Yawata, Takemi Otsuki, Yumika Isozaki, Tomohiro Fujii, Junichi Kurebayashi, Osamu Yamada, Masako Uno, Takashi Sugihara, Kenichiro Yata, Ayako Ueki, Hideho Wada, Haruko Sakaguchi

Publikováno v: British Journal of Haematology. 116:787-795

Recently, it was disclosed that all-trans retinoic acid (ATRA) inhibits myeloma cell growth by downregulating the interleukin 6 (IL-6)/IL-6 receptor (IL-6R) auto/paracrine loop, and upregulating p21/Cip1 cyclin-dependent kinase inhibitor (CDK-I), the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37eeb3510810620be55e84aa35aaf641
https://doi.org/10.1046/j.0007-1048.2002.03336.x

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IL-10 in Myeloma Cells

Autor: Hideho Wada, Haruko Sakaguchi, Tomohiro Fujii, Takashi Sugihara, Kenichiro Yata, Takemi Otsuki, Ayako Ueki, Masako Uno

Publikováno v: Leukemia & Lymphoma. 43:969-974

In addition to interleukin (IL)-6, IL-10 is considered as one of the most important cytokines regulating the proliferation and cellular characteristics of myeloma cells. It is still unclear from the clinical data how serum IL-10 levels of various sta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ad1b6d6d09868e16e7ccc3b4de95bb
https://doi.org/10.1080/10428190290021579

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Cell biological roles of IL-10 in myeloma cells

Autor: Hideho Wada, Kenichiro Yata, Ayako Ueki, Takashi Sugihara, Takemi Otsuki, Haruko Sakaguchi

Publikováno v: Journal of Clinical and Experimental Hematopathology. 42:1-9

IL-10,along with interleukin(IL)-6,are considered two of the most important cytokines that regulate the proliferation and cellular characteristics of myeloma cells. It remains unclear from the clinical data how levels of IL-10 in serum at various sta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b67b167161b27a05135c8cb57d573f54
https://doi.org/10.3960/jslrt.42.1

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