Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ayako Uchinaka"'
Autor:
Toyoaki Murohara, Kiyoshi Aoyama, Ayako Uchinaka, Naoki Azuma, Shiho Nakano, Hisashi Mizumoto, Moeko Minamiya, Mamoru Yoneda, Yuichiro Yamada, Yuki Komatsu, Kohzo Nagata
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-20 (2018)
Scientific Reports
Scientific Reports
The effects of heat-killed Lactobacillus plantarum L-137 (HK L-137) on chronic inflammation associated with metabolic disorders have remained unknown. We examined the effects of HK L-137 on cardiac and adipose tissue pathophysiology in DahlS.Z-Lepr f
Autor:
Natsumi Matsuura, Toyoaki Murohara, Yuichiro Yamada, Yuki Sano, Ayako Uchinaka, Kai Nagasawa, Yuri Kawashima, Shogo Ito, Mamoru Yoneda, Kohzo Nagata, Yusuke Sano
Publikováno v:
Annals of the New York Academy of Sciences. 1421:73-87
Melatonin regulates circadian rhythms but also has antioxidative and anti-inflammatory effects that ameliorate metabolic disorders. We investigated the effects of the selective melatonin agonist ramelteon on cardiac and adipose tissue pathology in th
Autor:
Ayako Uchinaka, Kohzo Nagata, Yoshitaka Maeno, Hirofumi Yamamoto, Yoshinosuke Hamada, Tsuyoshi Ban, Seiji Mori, Yoshiki Sawa, Naomasa Kawaguchi
Publikováno v:
Biochemical and Biophysical Research Communications. 491:714-720
SVVYGLR peptide (SV peptide) is a 7-amino-acid sequence with angiogenic properties that is derived from osteopontin in the extracellular matrix and promotes differentiation of fibroblasts to myofibroblast-like cells and the production of collagen typ
Autor:
Natsumi Matsuura, Toyoaki Murohara, Kohzo Nagata, Yasuko K Bando, Yusuke Sano, Shogo Ito, Mamoru Yoneda, Yuichiro Yamada, Kai Nagasawa, Ayako Uchinaka
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 311:H1360-H1366
Anesthesia can affect respiratory, circulatory, and endocrine systems but is necessary for certain experimental procedures such as echocardiography and blood sampling in small animals. We have now investigated the effects of four types of anesthesia
Autor:
Natsumi Matsuura, Kohzo Nagata, Toyoaki Murohara, Ayako Uchinaka, Kai Nagasawa, Yusuke Sano, Yoshiji Yamada, Shogo Ito
Publikováno v:
Obesity Science & Practice. 2:318-329
SummaryIntroduction n-3 Polyunsaturated fatty acids such as eicosapentaenoic acid (EPA), which are abundant in fish oil, have been shown to delay the onset of cardiovascular events. We previously established DahlS.Z-Leprfa/Leprfa (DS/obese) rats, whi
Autor:
Toyoaki Murohara, Yuki Komatsu, Minami Wataya, Mamoru Yoneda, Kanako Komuro, Kiyoshi Aoyama, Kohzo Nagata, Aoi Fujieda, Yumeno Kawai, Ayako Uchinaka
Publikováno v:
Circulation Research. 123
Objectives: B cells have emerged as a critical player in innate and adaptive immune responses. However, little is known about the role of B cells in obesity- and/or stress-induced immune responses. We previously reported that restraint stress exacerb
Autor:
Ayako Uchinaka, Yoshihito Horii, Shigeru Miyagawa, Yoshiki Sawa, Naomasa Kawaguchi, Yoko Mizuno, Yoshinosuke Hamada, Atsuhiro Saito, Nariaki Matsuura, Seiji Mori
Publikováno v:
Interactive CardioVascular and Thoracic Surgery. 21:506-514
OBJECTIVES: Osteopontin is a multifunctional cytokine that can modulate a variety of cellular activities, such as fibrotic response and inflammation. Osteopontin-derived peptide Ser-Val-Val-Tyr-Gly-Leu-Arg (SVVYGLR; SV) induces angiogenesis and the e
Autor:
Yoshiki Sawa, Nariaki Matsuura, Seiji Mori, Shigeru Miyagawa, Yoshinosuke Hamada, Atsuhiro Saito, Hirofumi Yamamoto, Naomasa Kawaguchi, Ayako Uchinaka
Publikováno v:
Molecular and Cellular Biochemistry. 408:191-203
Osteopontin (OPN) is involved in various physiological processes such as inflammatory and wound healing. However, little is known about the effects of OPN on these tissues. OPN is cleaved by thrombin, and cleavage of the N-terminal fragment exposes a
Autor:
Ayako Uchinaka, Shigeru Miyagawa, Yoshiki Sawa, Atsuhiro Saito, Nariaki Matsuura, Seiji Mori, Naomasa Kawaguchi, Yoshinosuke Hamada
Publikováno v:
Tissue Engineering and Regenerative Medicine. 12:162-171
In ischemic heart disease, cardiomyocyte death results from both necrosis and apoptosis, and the area of infarction gradually increases. The induction of therapeutic angiogenesis is a promising therapy for this condition. In the present study, we inv
Autor:
Ayako, Uchinaka, Yuri, Kawashima, Yuki, Sano, Shogo, Ito, Yusuke, Sano, Kai, Nagasawa, Natsumi, Matsuura, Mamoru, Yoneda, Yuichiro, Yamada, Toyoaki, Murohara, Kohzo, Nagata
Publikováno v:
Annals of the New York Academy of Sciences. 1421(1)
Melatonin regulates circadian rhythms but also has antioxidative and anti-inflammatory effects that ameliorate metabolic disorders. We investigated the effects of the selective melatonin agonist ramelteon on cardiac and adipose tissue pathology in th