Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Ayako Oda"'
Autor:
Keiichi Ishizu, Ayako Oda, Tada-nori Goto, Takafumi Kasaya, Toshiki Watanabe, Hideaki Machiyama
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Near-seafloor concentrated gas hydrates (GHs) containing large amounts of methane have been identified at various gas chimney sites. Although understanding the spatial distribution of GHs is fundamental for assessing their dissociation impac
Externí odkaz:
https://doaj.org/article/2e1bb6b2fefb422a875b8660eaff5925
Autor:
Chisato Yoshijima, Yosuke Suzuki, Ryota Tanaka, Hiroyuki Ono, Ayako Oda, Takashi Ozaki, Hirotaka Shibata, Hiroki Itoh, Keiko Ohno
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract In this study, plasma belimumab concentrations were measured over the course of treatment in systemic lupus erythematosus (SLE) patients on belimumab therapy, and intra‐ and interindividual variations in plasma belimumab concentration were
Externí odkaz:
https://doaj.org/article/110f7349bae04c588147b1235d8b168a
Autor:
Ayako Oda, Yosuke Suzuki, Haruki Sato, Teruhide Koyama, Masahiro Nakatochi, Yukihide Momozawa, Ryota Tanaka, Hiroyuki Ono, Ryosuke Tatsuta, Tadasuke Ando, Toshitaka Shin, Kenji Wakai, Keitaro Matsuo, Hiroki Itoh, Keiko Ohno
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 3, Pp n/a-n/a (2024)
Abstract Plasma 4β‐hydroxycholesterol (OHC) has drawn attention as an endogenous substrate indicating CYP3A activity. Plasma 4β‐OHC is produced by hydroxylation by CYP3A4 and CYP3A5 and by cholesterol autoxidation. Plasma 4α‐OHC is produced
Externí odkaz:
https://doaj.org/article/bd7b75ee273c4206b69a12d3a38422e0
Autor:
Hiroyuki Ono, Ryota Tanaka, Yosuke Suzuki, Ayako Oda, Haruki Sato, Ryosuke Tatsuta, Tadasuke Ando, Toshitaka Shin, Keiko Ohno, Hiroki Itoh
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 2, Pp n/a-n/a (2024)
Abstract Organic anion‐transporting polypeptides (OATP)1B are drug transporters mainly expressed in the sinusoidal membrane. Many studies have suggested that OATP1B activity is affected by genetic factor, the uremic toxin 3‐carboxy‐4‐methyl
Externí odkaz:
https://doaj.org/article/bb57347e4be7482abeaefe5b3729edfb
Autor:
Chisato Yoshijima, BSPharm, Yosuke Suzuki, PhD, Ayako Oda, BSPharm, Ryota Tanaka, PhD, Hiroyuki Ono, BSPharm, Hiroki Itoh, PhD, Keiko Ohno, PhD
Publikováno v:
Current Therapeutic Research, Vol 100, Iss , Pp 100738- (2024)
Background: Belimumab is the first antibody drug approved for systemic lupus erythematosus (SLE), and is a fully human monoclonal antibody that inhibits soluble B lymphocyte stimulator protein. In clinical trials, a composite index was used to assess
Externí odkaz:
https://doaj.org/article/5b77d26f5f1a49c2b8ef205c4172a692
Publikováno v:
BMC Veterinary Research, Vol 18, Iss 1, Pp 1-9 (2022)
Abstract Background Many veterinarians consider English Bulldogs to have a greater perianesthetic mortality risk. The aims of this study were to 1) determine total and anesthesia-related, perianesthetic mortality (PAM) rates in English Bulldogs (EB),
Externí odkaz:
https://doaj.org/article/9e0b0907fe234b56a9950e9caaae336e
Autor:
Yosuke Suzuki, Yuri Sasamoto, Teruhide Koyama, Chisato Yoshijima, Ayako Oda, Masahiro Nakatochi, Michiaki Kubo, Yukihide Momozawa, Ritei Uehara, Keiko Ohno
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 4, Pp 1403-1411 (2021)
Abstract Plasma coproporphyrin‐I (CP‐I) concentration is used as a sensitive and selective endogenous probe for phenotyping organic anion transporting polypeptides 1B (OATP1B) activity in many studies. CP‐I is produced in the process of heme sy
Externí odkaz:
https://doaj.org/article/8c1144d92f4a45bf802b3b712435c646
Autor:
Yosuke Suzuki, Ayako Oda, Jun Negami, Daiki Toyama, Ryota Tanaka, Hiroyuki Ono, Tadasuke Ando, Toshitaka Shin, Hiromitsu Mimata, Hiroki Itoh, Keiko Ohno
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 3, Pp 100184- (2022)
4β-Hydroxycholesterol (4β-OHC) is formed by Cytochrome P450 (CYP)3A and has drawn attention as an endogenous phenotyping probe for CYP3A activity. However, 4β-OHC is also increased by cholesterol autooxidation occurring in vitro due to dysregulate
Externí odkaz:
https://doaj.org/article/1905fd31ef1a4232918709404461654a
Autor:
Yukihiro Miwa, Hiroyuki Komatsu, Ari Shinojima, Ayako Oda, Mao Inagaki, Kensuke Usami, Minori Akasaka, Yoshitaka Kobayashi
Publikováno v:
Clinical Case Reports, Vol 9, Iss 11, Pp n/a-n/a (2021)
Abstract A 7.5‐year‐old intact male Japanese macaque was presented for evaluation of vision loss. After a complete ophthalmic examination, the patient was diagnosed with hypermature cataract in both eyes. After the cataract surgery, it was able t
Externí odkaz:
https://doaj.org/article/1fee3e0d800843969e39f34458864a23
Autor:
Takuma Watanabe, Ryota Tanaka, Yosuke Suzuki, Haruki Sato, Jun Negami, Chisato Yoshijima, Ayako Oda, Hiroyuki Ono, Ryosuke Tatsuta, Keiko Ohno, Hiroki Itoh
Publikováno v:
British journal of clinical pharmacologyREFERENCES.
Cyclosporin A (CyA) has potent inhibitory activity on organic anion transporting polypeptide 1B (OATP1B), causing drug-drug interactions with its substrate drugs. 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), a uraemic toxin, has also been su