Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ayako Nishimoto"'
Autor:
Ayako Nishimoto-Kakiuchi, Izumi Sato, Kiyotaka Nakano, Hiroshi Ohmori, Yoko Kayukawa, Hiromi Tanimura, Sachiya Yamamoto, Yuichiro Sakamoto, Genki Nakamura, Atsuhiko Maeda, Kentaro Asanuma, Atsuhiko Kato, Tadashi Sankai, Ryo Konno, Hisafumi Yamada-Okabe
Publikováno v:
Science Translational Medicine. 15
Current pharmacological treatments for endometriosis are limited to hormonal agents that can relieve pain but cannot cure the disease. Therefore, the development of a disease-modifying drug for endometriosis is an unmet medical need. By studying huma
Autor:
Klein, Alice (AUTHOR)
Publikováno v:
New Scientist. 3/4/2023, Vol. 257 Issue 3428, p24-24. 1/3p.
Autor:
Mayu Tujimoto, Yasuhiro Oono, Mika Sakaguchi, Ayako Nishimoto, Kiyonori Takenaka, Masahito Minami
Publikováno v:
Choonpa Igaku. 45:605-610
Autor:
Hiromitsu Kawata, Ayako Nishimoto, Nobuyuki Ishikura, Takao Houjo, Robert L. Vessella, Hitoshi Yoshino, Takashi Emura, Toshito Nakagawa, Kazutaka Tachibana, Haruhiko Sato, Miho Watanabe, Ryo Nakamura, Takuya Shiraishi, Masateru Ohta, Toshiaki Tsunenari, Yuko Aoki, Akie Honma, Eva Corey
Publikováno v:
International Journal of Oncology. 46:1560-1572
Resistance of prostate cancer to castration is currently an unavoidable problem. The major mechanisms underlying such resistance are androgen receptor (AR) overexpression, androgen-independent activation of AR, and AR mutation. To address this proble
Autor:
Takuya Shiraishi, Ayako Nishimoto, Hitoshi Yoshino, Hiromitsu Kawata, Shinichi Arai, Haruhiko Sato, Kazutaka Tachibana, Toshito Nakagawa, Nobuyuki Ishikura, Ryo Nakamura
Publikováno v:
The Prostate. 71:1344-1356
BACKGROUND Castration-resistant prostate cancer (CRPC) is still dependent on androgen receptor (AR) signaling. We previously reported that a novel nonsteroidal AR pure antagonist, CH4933468, which is a thiohydantoin derivative with a sulfonamide side
Autor:
Takuya Shiraishi, Ayako Nishimoto, Toshito Nakagawa, Akie Honma, Masateru Ohta, Hitoshi Yoshino, Kazutaka Tachibana, Nobuyuki Ishikura, Toshiaki Tsunenari, Kentaro Furumoto, Ryo Nakamura, Kazuya Kimura, Hiromitsu Kawata, Haruhiko Sato, Miho Watanabe, Noriyuki Takata, Takashi Emura
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:8150-8157
A series of 5,5-dimethylthiohydantoin derivatives were synthesized and evaluated for androgen receptor pure antagonistic activities for the treatment of castration-resistant prostate cancer. Since CH4933468, which we reported previously, had a proble
Autor:
Yuko Aoki, Miho Watanabe, Toshiaki Tsunenari, Ayako Nishimoto, Hiromitsu Kawata, Nobuyuki Ishikura
Publikováno v:
The Prostate. 70:745-754
BACKGROUND Various hormone refractory prostate cancer cell models have been established with androgen depletion and have helped to clarify the mechanism for the transition into androgen-depletion independent status. However, the mechanism of bicaluta
Publikováno v:
The Prostate. 70:457-466
BACKGROUND Hormone refractoriness is a lethal event for advanced prostate cancer patients, but the mechanisms of the disease are not well elucidated, especially for the so-called “outlaw” pathways of androgen receptor (AR)-dependent, androgen-ind
Autor:
Masayuki Yamato, Joseph Yang, Ayako Nishimoto, Chinatsu Kohno, Hidekazu Sekine, Teruo Okano, Fumio Fukai
Publikováno v:
Biomaterials. 26(33):6415-6422
While tissue engineering has long been thought to possess enormous potential, conventional applications using biodegradable scaffolds have limited the field's progress, demonstrating a need for new methods. We have previously developed cell sheet eng
Autor:
NOBUYUKI ISHIKURA, HIROMITSU KAWATA, AYAKO NISHIMOTO, RYO NAKAMURA, TOSHIAKI TSUNENARI, MIHO WATANABE, KAZUTAKA TACHIBANA, TAKUYA SHIRAISHI, HITOSHI YOSHINO, AKIE HONMA, TAKASHI EMURA, MASATERU OHTA, TOSHITO NAKAGAWA, TAKAO HOUJO, COREY, EVA, VESSELLA, ROBERT L., YUKO AOKI, HARUHIKO SATO
Publikováno v:
International Journal of Oncology; 2015, Vol. 46 Issue 4, p1560-1572, 13p