Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ayako Kitano"'
Autor:
Ayako Kitano, Takeo Shimasaki, Yuri Chikano, Mitsutoshi Nakada, Mayumi Hirose, Tomomi Higashi, Yasuhito Ishigaki, Yoshio Endo, Takahisa Takino, Hiroshi Sato, Yoshimichi Sai, Ken-Ichi Miyamoto, Yoshiharu Motoo, Kazuyuki Kawakami, Toshinari Minamoto
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55289 (2013)
The major obstacles to treatment of pancreatic cancer are the highly invasive capacity and resistance to chemo- and radiotherapy. Glycogen synthase kinase 3β (GSK3β) regulates multiple cellular pathways and is implicated in various diseases includi
Externí odkaz:
https://doaj.org/article/7a4aacd7bd564a35bf16a75151dc2583
Autor:
Toshinari Minamoto, Mitsutoshi Nakada, Ken-ichi Miyamoto, Hiroshi Sato, Yutaka Hayashi, Yoshimichi Sai, Takahisa Takino, Ilya V. Pyko, Ayako Kitano-Tamura, Hemragul Sabit, Takuya Furuta, Takahiro Domoto, Yuri Chikano
Effects of GSK3beta inhibition on the formation of invadopodium-like microstructures and matrix degradation by U251 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df23cca58028b320778992d80af1ae7
https://doi.org/10.1158/1535-7163.22503222
https://doi.org/10.1158/1535-7163.22503222
Autor:
Toshinari Minamoto, Mitsutoshi Nakada, Ken-ichi Miyamoto, Hiroshi Sato, Yutaka Hayashi, Yoshimichi Sai, Takahisa Takino, Ilya V. Pyko, Ayako Kitano-Tamura, Hemragul Sabit, Takuya Furuta, Takahiro Domoto, Yuri Chikano
Source and working dilutions of the primary antibodies used for Western blotting, immunofluorescence and immunohistochemical staining and pull-down assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ead367b6b93387baf70722fdb8f1f3d
https://doi.org/10.1158/1535-7163.22503216.v1
https://doi.org/10.1158/1535-7163.22503216.v1
Autor:
Yoshimichi Sai, Mitsutoshi Nakada, Yuri Chikano, Takahisa Takino, Yutaka Hayashi, Toshinari Minamoto, Ilya V. Pyko, Takahiro Domoto, Hemragul Sabit, Ayako Kitano-Tamura, Hiroshi Sato, Ken-ichi Miyamoto, Takuya Furuta
Publikováno v:
Molecular Cancer Therapeutics. 14:564-574
The failure of current treatment options for glioblastoma stems from their inability to control tumor cell proliferation and invasion. Biologically targeted therapies offer great hope and one promising target is glycogen synthase kinase-3β (GSK3β),
Autor:
Yuri Chikano, Yoshio Endo, Ayako Kitano, Kazuyuki Kawakami, Takahisa Takino, Yoshiharu Motoo, Tomomi Higashi, Yasuhito Ishigaki, Hiroshi Sato, Ken-ichi Miyamoto, Takeo Shimasaki, Toshinari Minamoto, Yoshimichi Sai, Mayumi Hirose, Mitsutoshi Nakada
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55289 (2013)
PLoS ONE
PLoS ONE
Background and Purpose: The major obstacles to treatment of pancreatic cancer are the highly invasive capacity and resistance to chemo- and radiotherapy. Glycogen synthase kinase 3β (GSK3β) regulates multiple cellular pathways and is implicated in
Autor:
Susumu Shimura, Ayako Kitano, Akiko Yamashita, Yoshio Itoh, Takuo Okuda, Tsutomu Hatano, Takashi Yoshida
Publikováno v:
NIPPON SHOKUHIN KOGYO GAKKAISHI. 41:847-850
Luteolin was isolated as a lipase inhibitor from Cassia mimosoides var. nomame. During an investigation on the inhibitory effects of the other related flavonoids on lipase, flavonols (kaempferol, myricetin and quercetin) exhibited activity comparable
Autor:
Tsutomu Takegami, Takanobu Takata, Yoshiharu Motoo, Xia Zhao, Takeo Shimasaki, Toshinari Minamoto, Naoki Nakaya, Hideo Nakajima, Ayako Kitano, Itaru Sato, Yasuhito Ishigaki, Takuji Tanaka, Naohisa Tomosugi, Kazuyuki Kawakami, Yuka Nakamura
Publikováno v:
Journal of gastroenterology. 47(3)
Pancreatic cancer is obstinate and resistant to gemcitabine, a standard chemotherapeutic agent for the disease. We previously showed a therapeutic effect of glycogen synthase kinase-3β (GSK3β) inhibition against gastrointestinal cancer and glioblas
Autor:
Takeo Shimasaki, Toshinari Minamoto, Takanobu Takata, Nobuhiko Ueda, Tsutomu Takegami, Ayako Kitano, Tomiyasu Arisawa, Yoshiharu Motoo, Naohisa Tomosugi, Takeo Kosaka, Yasuhito Ishigaki
Publikováno v:
Gastroenterology. 144:S-871
Publikováno v:
Annals of Oncology. 23:xi122
Purpose The major obstacles to effective treatment of pancreatic cancer are the highly invasive nature of this tumor type and its resistance to chemo- and radiotherapy. Glycogen synthase kinase 3β (GSK3β) is a serine/threonine protein kinase that r
Publikováno v:
Journal of Carcinogenesis, Vol 11, Iss 1, Pp 15-15 (2012)
Journal of Carcinogenesis
Journal of Carcinogenesis
Development and progression of pancreatic cancer involves general metabolic disorder, local chronic inflammation, and multistep activation of distinct oncogenic molecular pathways. These pathologic processes result in a highly invasive and metastatic