Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ayako, Matsunuma"'
Autor:
Ayako Matsunuma, Noboru Horiuchi
Publikováno v:
Archives of Biochemistry and Biophysics. 463:118-127
Leptin, the ob gene product secreted by adipocytes, controls overall energy balance. We previously showed that leptin administration to leptin-deficient obese (ob/ob) mice suppressed mRNA expression and activity of renal 25-hydroxyvitamin D 3 -1α-hy
Autor:
Noboru Horiuchi, Ayako Matsunuma
Publikováno v:
Journal of Oral Biosciences. 49:97-104
Leptin, a hormone secreted by adipocytes, acts on the hypothalamus to reduce appetite and inhibit body weight gain. Leptin has pleiotropic actions on bone, gonadal hormone secretion, the pancreas, immune tissues, and vascular organs. Leptin-deficient
Publikováno v:
Endocrinology. 145:1367-1375
Leptin, the ob gene product secreted by adipocytes, controls overall energy balance. We investigated leptin effects on bone metabolism using male leptin-deficient obese (ob/ob) mice, which had lower bone mineral density (BMD) and shorter femurs than
Autor:
Toru Yanagawa, Hiroshi Yoshida, Noboru Horiuchi, Izuru Kurahashi, Toyonobu Maeda, Ayako Matsunuma
Publikováno v:
Journal of Cellular Biochemistry. 92:458-471
Statins inhibit 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, which catalyzes conversion of HMG-CoA to mevalonate, a rate-limiting step in cholesterol synthesis. The present study was undertaken to understand the events of osteoblast dif
Publikováno v:
Endocrine. 17:109-118
Chronic glucocorticoid therapy causes rapid bone loss and clinical osteoporosis. We previously found that dexamethasone, a potent glucocorticoid, increased renal expression of vitamin D-24-hydroxylase, which degrades such vitamin D metabolites as 25-
Publikováno v:
Human Genetics. 100:163-166
A DD genotype of the angiotensin I-converting enzyme gene has been implicated in various diseases. However, genotype frequencies differ between previous reports, and data on the association of DD genotype with disease are sometimes conflicting. Altho
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 25(8)
Leptin is the LEP (ob) gene product secreted by adipocytes. We previously reported that leptin decreases renal expression of the 25-hydroxyvitamin D3 1α-hydroxylase (CYP27B1) gene through the leptin receptor (ObRb) by indirectly acting on the proxim
Publikováno v:
Endocrine. 17(2)
Chronic glucocorticoid therapy causes rapid bone loss and clinical osteoporosis. We previously found that dexamethasone, a potent glucocorticoid, increased renal expression of vitamin D-24-hydroxylase, which degrades such vitamin D metabolites as 25-
Publikováno v:
Diabetes Care. 19:543-544
Publikováno v:
The Lancet. 348:1310