Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ayako, Aihara"'
Autor:
Ayako Aihara, Tomo Koike, Natsuki Abe, Sou Nakamura, Akira Sawaguchi, Takanori Nakamura, Naoshi Sugimoto, Hiromitsu Nakauchi, Taito Nishino, Koji Eto
Publikováno v:
Blood Advances, Vol 1, Iss 7, Pp 468-476 (2017)
Abstract: Signaling by thrombopoietin (TPO) in complex with its receptor, c-MPL, is critical for hematopoietic stem cell (HSC) homeostasis and platelet generation. Here we show that TA-316, a novel chemically synthesized c-MPL agonist (CMA), is usefu
Externí odkaz:
https://doaj.org/article/4d5a5e1551ec4c2eb31fd0766b5ae58e
Autor:
Yuriko, Shiozawa, Akiyo, Itagaki, Yuka, Nojiri, Noriko, Aizawa, Ayako, Aihara, Tatsuya, Suzuki, Shoko, Kaneko
Publikováno v:
獨協医科大学看護学部紀要 = Bulletin of Dokkyo Medical University School of Nursing. 12:39-48
【目的】 大学における看護基礎教育において保健師養成が選択制に移行する一方で，国が行う地域包括ケアシステムの推進に向けて，地域を包括的・継続的に捉えて看護を展開する看護
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::62f74714f34cb8d84b6366c9c83c1023
http://id.nii.ac.jp/1199/00002159/
http://id.nii.ac.jp/1199/00002159/
Autor:
Ayako Aihara, Takumi Iwawaki, Natsuki Abe-Fukasawa, Keiichiro Otsuka, Koichiro Saruhashi, Takumi Mikashima, Taito Nishino
Publikováno v:
Journal of Biological Chemistry. 298:101779
Although 3D cell culture models are considered to reflect the physiological microenvironment and exhibit high concordance with in vivo conditions, one disadvantage has been that cell proliferation is slower in 3D culture as compared to 2D culture. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88086029e822072066dbdb4d300fa84e
https://doi.org/10.1016/j.jbc.2022.101779
https://doi.org/10.1016/j.jbc.2022.101779
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Abe-Fukasawa, N, Otsuka, K, Aihara, A, Itasaki, N & Nishino, T 2018, ' Novel 3D Liquid Cell Culture Method for Anchorage-independent Cell Growth, Cell Imaging and Automated Drug Screening ', Scientific Reports, vol. 8, no. 1, 3627 . https://doi.org/10.1038/s41598-018-21950-5
Scientific Reports
Abe-Fukasawa, N, Otsuka, K, Aihara, A, Itasaki, N & Nishino, T 2018, ' Novel 3D Liquid Cell Culture Method for Anchorage-independent Cell Growth, Cell Imaging and Automated Drug Screening ', Scientific Reports, vol. 8, no. 1, 3627 . https://doi.org/10.1038/s41598-018-21950-5
Cells grown in three-dimensional (3D) cultures are more likely to have native cell-cell and cell-matrix interactions than in 2D cultures that impose mechanical constraints to cells. However, most 3D cultures utilise gel matrix which, while serving as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3815e58648fb4a017e18078348fe4a07
http://link.springer.com/article/10.1038/s41598-018-21950-5
http://link.springer.com/article/10.1038/s41598-018-21950-5
Autor:
Iwawaki Takumi, Taito Nishino, Ayako Aihara, Shun Uemura, Atsushi Iwama, Hirohito Sone, Masayuki Yamashita, Shuhei Koide, Jun Takizawa, Motohiko Oshima, Yaeko Nakajima-Takagi, Masayoshi Masuko
Publikováno v:
Blood. 138:199-199
Adult hematopoietic stem cells (HSCs) reside and are protected in a unique bone marrow (BM) microenvironment, termed the HSC niche, which consists mainly of vascular endothelial cells (EC) and EC-associated mesenchymal stromal cells (MSC). Myeloablat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a7a46945af0fbdca22c7cb12c05c24f
https://doi.org/10.1182/blood-2021-148212
https://doi.org/10.1182/blood-2021-148212
Publikováno v:
Cancer Science
Anticancer drug discovery efforts have used 2-D cell-based assay models, which fail to forecast in vivo efficacy and result in a lower success rate of clinical approval. Recent 3-D cell culture models are expected to bridge the gap between 2-D and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9a3630aca56357c3603b6b26d39b55
https://doi.org/10.1111/cas.13095
https://doi.org/10.1111/cas.13095