Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ayaka Tokumura"'
Autor:
Tadashi Yamamuro, Shuhei Nakamura, Yu Yamano, Tsutomu Endo, Kyosuke Yanagawa, Ayaka Tokumura, Takafumi Matsumura, Kiyonori Kobayashi, Hideto Mori, Yusuke Enokidani, Gota Yoshida, Hitomi Imoto, Tsuyoshi Kawabata, Maho Hamasaki, Akiko Kuma, Sohei Kuribayashi, Kentaro Takezawa, Yuki Okada, Manabu Ozawa, Shinichiro Fukuhara, Takashi Shinohara, Masahito Ikawa, Tamotsu Yoshimori
Publikováno v:
PLoS Genetics, Vol 17, Iss 8 (2021)
Autophagy degrades unnecessary proteins or damaged organelles to maintain cellular function. Therefore, autophagy has a preventive role against various diseases including hepatic disorders, neurodegenerative diseases, and cancer. Although autophagy i
Externí odkaz:
https://doaj.org/article/d2de1c9609cc4eabada556ef6ddc88f3
Autor:
Shuhei Nakamura, Masaki Oba, Mari Suzuki, Atsushi Takahashi, Tadashi Yamamuro, Mari Fujiwara, Kensuke Ikenaka, Satoshi Minami, Namine Tabata, Kenichi Yamamoto, Sayaka Kubo, Ayaka Tokumura, Kanako Akamatsu, Yumi Miyazaki, Tsuyoshi Kawabata, Maho Hamasaki, Koji Fukui, Kazunori Sango, Yoshihisa Watanabe, Yoshitsugu Takabatake, Tomoya S. Kitajima, Yukinori Okada, Hideki Mochizuki, Yoshitaka Isaka, Adam Antebi, Tamotsu Yoshimori
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Autophagic activity decreases with age via unknown mechanisms. Here the authors show that expression of the negative autophagy regulator Rubicon increases with age, that its genetic ablation improves lifespan and ameliorates a number of age-associate
Externí odkaz:
https://doaj.org/article/8aa18fda9b7a4cc7bd3ad05d003b9c17
Autor:
Shuhei Nakamura, Saki Shigeyama, Satoshi Minami, Takayuki Shima, Shiori Akayama, Tomoki Matsuda, Alessandra Esposito, Gennaro Napolitano, Akiko Kuma, Tomoko Namba-Hamano, Jun Nakamura, Kenichi Yamamoto, Miwa Sasai, Ayaka Tokumura, Mika Miyamoto, Yukako Oe, Toshiharu Fujita, Seigo Terawaki, Atsushi Takahashi, Maho Hamasaki, Masahiro Yamamoto, Yukinori Okada, Masaaki Komatsu, Takeharu Nagai, Yoshitsugu Takabatake, Haoxing Xu, Yoshitaka Isaka, Andrea Ballabio, Tamotsu Yoshimori
Publikováno v:
Nature Cell Biology. 24:1677-1679
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8319f10c56d15336a4f8a2958f9f6cde
https://doi.org/10.1038/s41556-022-01017-4
https://doi.org/10.1038/s41556-022-01017-4
Autor:
Satoshi Minami, Ayaka Tokumura, Tatsuya Shioda, Sayaka Kubo, Hidesato Ogawa, Megumi Tsuchiya, Shuhei Nakamura, Toshiharu Fujita, Li Yu, Maho Hamasaki, Tamotsu Yoshimori, Yoshitaka Isaka
Publikováno v:
Journal of Cell Science. 134
TFEB, a basic helix-loop-helix transcription factor, is a master regulator of autophagy, lysosome biogenesis and lipid catabolism. Compared to posttranslational regulation of TFEB, the regulation of TFEB mRNA stability remains relatively uncharacteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe8e0eb2ec757121a498819af580686f
https://doi.org/10.1242/jcs.248203
https://doi.org/10.1242/jcs.248203
Autor:
Hitomi Yamamoto-Imoto, Satoshi Minami, Tatsuya Shioda, Yurina Yamashita, Shinsuke Sakai, Shihomi Maeda, Takeshi Yamamoto, Shinya Oki, Mizuki Takashima, Tadashi Yamamuro, Kyosuke Yanagawa, Ryuya Edahiro, Miki Iwatani, Mizue So, Ayaka Tokumura, Toyofumi Abe, Ryoichi Imamura, Norio Nonomura, Yukinori Okada, Donald E. Ayer, Hidesato Ogawa, Eiji Hara, Yoshitsugu Takabatake, Yoshitaka Isaka, Shuhei Nakamura, Tamotsu Yoshimori
Publikováno v:
Cell Reports. 38:110444
Accumulation of senescent cells affects organismal aging and the prevalence of age-associated disease. Emerging evidence suggests that activation of autophagy protects against age-associated diseases and promotes longevity, but the roles and regulato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4032ba94a04b9e59cadf556c264cea78
https://doi.org/10.1016/j.celrep.2022.110444
https://doi.org/10.1016/j.celrep.2022.110444
Autor:
Miwa Sasai, Yukako Oe, Yukinori Okada, Takayuki Shima, Yoshitsugu Takabatake, Akiko Kuma, Takeharu Nagai, Gennaro Napolitano, Maho Hamasaki, Mika Miyamoto, Tamotsu Yoshimori, Yoshitaka Isaka, Shiori Akayama, Shuhei Nakamura, Alessandra Esposito, Seigo Terawaki, Satoshi Minami, Atsushi Takahashi, Ayaka Tokumura, Tomoko Namba-Hamano, Masahiro Yamamoto, Masaaki Komatsu, Saki Shigeyama, Toshiharu Fujita, Kenichi Yamamoto, Jun Nakamura, Tomoki Matsuda, Haoxing Xu, Andrea Ballabio
Sensing and clearance of dysfunctional lysosomes is critical for cellular homeostasis. Here we show that transcription factor EB (TFEB)—a master transcriptional regulator of lysosomal biogenesis and autophagy—is activated during the lysosomal dam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0217e20e6234639304a071a87c0c4c2
http://hdl.handle.net/11588/828756
http://hdl.handle.net/11588/828756
