Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ayaka Tatara"'
Autor:
Yukihiro Ohno, Saki Shimizu, Ayaka Tatara, Takuji Imaoku, Takahiro Ishii, Masashi Sasa, Tadao Serikawa, Takashi Kuramoto
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0123529 (2015)
Genetic factors are thought to play a major role in the etiology of essential tremor (ET); however, few genetic changes that induce ET have been identified to date. In the present study, to find genes responsible for the development of ET, we employe
Externí odkaz:
https://doaj.org/article/ef3fc090adad466f98c272707b2bb4af
Autor:
Kazuhito Ikeda, Masao Goda, Shiori Taga, Kantaro Nishigori, Takeshi Enomoto, Yuki Fujii, Ayaka Tatara, Atsushi Kitamura, Mami Kamada, Takashi Hashimoto, Yohei Nishizato
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 371:692-702
In our drug discovery program, we identified a novel orally available and brain-penetrant phosphodiesterase (PDE) 1 inhibitor, 3-methyl-7-(tetrahydro-2H-pyran-4-yl)-2-{[trans-4-(trifluoromethyl)cyclohexyl]-methoxy}imidazo[5,1-f][1,2,4]triazin-4(3H)-o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25128c74d0bcc6595cd32cfaea38951d
https://doi.org/10.1124/jpet.119.260869
https://doi.org/10.1124/jpet.119.260869
Autor:
Midori Ochiai, Miyuki Tamura, Yusuke Mizobe, Shoko Minamimoto, Atsushi Masui, Yukihiro Ohno, Saki Shimizu, Yuto Mizuguchi, Ayaka Tatara
Publikováno v:
Pharmacology Biochemistry and Behavior. 138:14-19
Blonanserin is a new atypical antipsychotic drug that shows high affinities to dopamine D2 and 5-HT2 receptors; however, the mechanisms underlying its atypicality are not fully understood. In this study, we evaluated the antipsychotic properties of A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d458bbb285171e6035a59c78fd41f68
https://doi.org/10.1016/j.pbb.2015.09.003
https://doi.org/10.1016/j.pbb.2015.09.003
Autor:
Kazuhito Ikeda, Takeshi Enomoto, Masao Goda, Yohei Nishizato, Mami Kamada, Yuki Fujii, Ayaka Tatara, Atsushi Kitamura, Shiori Taga, Takashi Hashimoto, Kantaro Nishigori
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 93:2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86156e4f0a8613be360413ed6fd03890
https://doi.org/10.1254/jpssuppl.93.0_2-p-163
https://doi.org/10.1254/jpssuppl.93.0_2-p-163
Autor:
Saki Andatsu, Saki Shimizu, Maho Sato, Tomone Sugiuchi, Satoshi Miyoshi, Tomoya Kizu, Ayaka Tatara, Yukihiro Ohno
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 50:157-162
Dopamine D(3) receptors are highly expressed in the cerebellum; however, their pathophysiological functions are not fully understood. Here, we conducted microinjection studies to clarify the role of cerebellar D(3) receptors in modulating locomotion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9a9017cc612144a029b3acfc28b5b6
https://doi.org/10.1016/j.pnpbp.2013.12.013
https://doi.org/10.1016/j.pnpbp.2013.12.013
Autor:
Mika Egawa, Ayaka Tatara, Motoki Okano, Yukihiro Ohno, Junta Imaki, Yuto Mizuguchi, Chikako Yoshihara, Saki Shimizu, Atsushi Masui, Masashi Sasa
Publikováno v:
Neuropharmacology. 63:547-554
Spontaneously hypertensive rats (SHR) are widely used as a rat model of attention deficit/hyperactivity disorder (AD/HD). Here, we conducted neurochemical and behavioral studies in SHR to clarify the topographical alterations in neurotransmissions li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::332f7d23964b506a5e34b777e1213c99
https://doi.org/10.1016/j.neuropharm.2012.04.031
https://doi.org/10.1016/j.neuropharm.2012.04.031
Autor:
Takashi Kuramoto, Takuji Imaoku, Saki Shimizu, Tadao Serikawa, Masashi Sasa, Takahiro Ishii, Yukihiro Ohno, Ayaka Tatara
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0123529 (2015)
PLoS ONE
PLoS ONE
Genetic factors are thought to play a major role in the etiology of essential tremor (ET); however, few genetic changes that induce ET have been identified to date. In the present study, to find genes responsible for the development of ET, we employe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a8ac34bccb9b318d52922f7f4d2454
http://europepmc.org/articles/PMC4430019?pdf=render
http://europepmc.org/articles/PMC4430019?pdf=render
Autor:
Yuto Mizuguchi, Tomoya Kizu, Ayaka Tatara, Yukihiro Ohno, Tomoki Morimoto, Saki Andatsu, Saki Shimizu, Mai Fujiwara, Akira Sobue
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 46
We previously demonstrated that 5-HT stimulants, including selective serotonin reuptake inhibitors (SSRIs), potentiated antipsychotic-induced extrapyramidal symptoms (EPS) by stimulating 5-HT2A/2C, 5-HT3 and 5-HT6 receptors. Here, we studied the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50de8bd57a4a8aee1f9a60b353dc2af8
https://pubmed.ncbi.nlm.nih.gov/23838274
https://pubmed.ncbi.nlm.nih.gov/23838274
Autor:
Yukihiro, Ohno, Motoki, Okano, Atsushi, Masui, Junta, Imaki, Mika, Egawa, Chikako, Yoshihara, Ayaka, Tatara, Yuto, Mizuguchi, Masashi, Sasa, Saki, Shimizu
Publikováno v:
Neuropharmacology. 63(4)
Spontaneously hypertensive rats (SHR) are widely used as a rat model of attention deficit/hyperactivity disorder (AD/HD). Here, we conducted neurochemical and behavioral studies in SHR to clarify the topographical alterations in neurotransmissions li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5cdf7c63b435c41d66d2d5c77e8cc2b6
https://pubmed.ncbi.nlm.nih.gov/22580374
https://pubmed.ncbi.nlm.nih.gov/22580374
Publikováno v:
Neuropharmacology. 60(2-3)
Previous studies showed that 5-HT(1A) and 5-HT(2) receptors play an important role in controlling the extrapyramidal motor disorders. However, the functions of other 5-HT receptor subtypes remain elusive. To elucidate the role of 5-HT receptors, spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bcb5c34afc3d259163c4f964c252202
https://pubmed.ncbi.nlm.nih.gov/20813116
https://pubmed.ncbi.nlm.nih.gov/20813116