Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ayaka Orii"'
Autor:
Yaeko Kobayashi, Ya Li Zhai, Toshio Nikaido, Shingo Fujii, Ikuo Konishi, Atsushi Mori, Ayaka Orii
Publikováno v:
International Journal of Gynecological Pathology. 18:20-28
The expression of estrogen receptor (ER), progesterone receptor (PR), tumor suppressor oncogene p53, and Ki-67 was compared in uterine smooth muscle tumors, including leiomyosarcoma (LMS), tumor of uncertain malignant potential (UMP), cellular leiomy
Publikováno v:
International Journal of Gynecological Pathology. 17:336-342
Mast cells (MCs) have been reported in the myometrium and uterine smooth muscle tumors. We examined the number of MCs in various uterine smooth muscle tumors (including leiomyosarcomas) and assessed whether this feature might be of value in their pat
Autor:
Takashi Kusakari, Kenji Takakura, Hiroaki Shime, Toshio Nikaido, Shingo Fujii, Masatoshi Kariya, Takanobu Kanamori, Chika Momma, Ken Fukuhara, Ayaka Orii, Yuko Tsuruta
Publikováno v:
The Journal of clinical endocrinology and metabolism. 87(12)
Uterine leiomyoma is a mesenchymal tumor composed of smooth muscle cells with fibrous tissues and many mast cells. Tranilast is known to suppress fibrosis or to work as a mast cell stabilizer and is reported to inhibit proliferation of vascular smoot
Autor:
Kiyoshi Kato, Ya Li Zhai, Masatoshi Kariya, Ayaka Orii, Junji Yodoi, Ikuo Konishi, Hiroshi Masutani, Toshio Nikaido, Shingo Fujii
Publikováno v:
The Journal of clinical endocrinology and metabolism. 87(8)
Uterine leiomyomas are the most common benign smooth muscle tumors in the myometrium. The expression of redox factor 1 (Ref-1), a DNA repair enzyme and redox-modifying factor, was studied in the myometrium and uterine smooth muscle tumors to investig
Autor:
Ken Fukuhara, Masatoshi Kariya, Masato Kita, Ayaka Orii, Hiroaki Shime, Chika Kosaka, Shingo Fujii, Takanobu Kanamori, Jun Fujita
Publikováno v:
The Journal of clinical endocrinology and metabolism. 87(4)
Secreted frizzled related protein 1 (sFRP1) is a modulator of Wnt signaling. Recently, aberrations of Wnt signaling were reported to be involved in the pathology of various human neoplasms. We investigated the expression and function of sFRP1 in uter
Frequent occurrence of loss of heterozygosity among tumor suppressor genes in uterine leiomyosarcoma
Publikováno v:
Gynecologic oncology. 75(3)
Objective. Leiomyosarcoma of the uterus is a rare smooth muscle tumor; it is extremely malignant and the rates of local recurrence and metastasis are high. Since tumor suppressor genes are commonly altered in malignant tumors, it is possible that mut
Publikováno v:
British Journal of Cancer
We examined bcl-2 expression as well as p53 expression and mutation in human uterine smooth muscle tumours to determine the influence of bcl-2 expression on prognosis in patients with uterine leiomyosarcomas. bcl-2 protein was expressed in nearly all