Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ayaka Harada"'
Autor:
Kazutoshi Tani, Ryo Kanno, Ayaka Harada, Yuki Kobayashi, Akane Minamino, Shinji Takenaka, Natsuki Nakamura, Xuan-Cheng Ji, Endang R. Purba, Malgorzata Hall, Long-Jiang Yu, Michael T. Madigan, Akira Mizoguchi, Kenji Iwasaki, Bruno M. Humbel, Yukihiro Kimura, Zheng-Yu Wang-Otomo
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract The mesophilic purple sulfur phototrophic bacterium Allochromatium (Alc.) vinosum (bacterial family Chromatiaceae) has been a favored model for studies of bacterial photosynthesis and sulfur metabolism, and its core light-harvesting (LH1) co
Externí odkaz:
https://doaj.org/article/853c64be01c04d92a22b83898867c6a5
Autor:
Haruka Takenouchi, Takatoshi Anno, Ayaka Harada, Hayato Isobe, Yukiko Kimura, Fumiko Kawasaki, Kohei Kaku, Koichi Tomoda, Hideyo Fujiwara, Hideaki Kaneto
Publikováno v:
BMC Endocrine Disorders, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background The hallmark of hyperparathyroidism is hypersecretion of parathyroid hormone (PTH) which results in hypercalcemia and hypophosphatemia. While hypercalcemia due to malignancy is often brought about by PTH-related protein in adults,
Externí odkaz:
https://doaj.org/article/567076fb1701474787c8ea12a3a5696d
Autor:
Ayaka Harada, Hiroyasu Tsutsuki, Tianli Zhang, Kinnosuke Yahiro, Tomohiro Sawa, Takuro Niidome
Publikováno v:
Nanomaterials, Vol 12, Iss 13, p 2161 (2022)
Advances in drug delivery systems (DDSs) have enabled the specific delivery of drugs to target cells. Subtilase cytotoxin (SubAB) produced by certain enterohemorrhagic Escherichia coli strains induces endoplasmic reticulum (ER) stress and suppresses
Externí odkaz:
https://doaj.org/article/15ba408034274fc29b5c8652a3aecdc9
Autor:
Waliul Islam, Shintaro Kimura, Rayhanul Islam, Ayaka Harada, Katsuhiko Ono, Jun Fang, Takuro Niidome, Tomohiro Sawa, Hiroshi Maeda
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 6, p 487 (2021)
For more than three decades, enhanced permeability and retention (EPR)-effect-based nanomedicines have received considerable attention for tumor-selective treatment of solid tumors. However, treatment of advanced cancers remains a huge challenge in c
Externí odkaz:
https://doaj.org/article/4fa296db1d1a403eb60b51539c418045
Autor:
Shingo Aizawa, Miki Senda, Ayaka Harada, Naoki Maruyama, Tetsuo Ishida, Toshiro Aigaki, Akihito Ishigami, Toshiya Senda
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53706 (2013)
The senescence marker protein-30 (SMP30), which is also called regucalcin, exhibits gluconolactonase (GNL) activity. Biochemical and biological analyses revealed that SMP30/GNL catalyzes formation of the γ-lactone-ring of L-gulonate in the ascorbic
Externí odkaz:
https://doaj.org/article/a322213e27734ed3be756a0637318a3a
Autor:
Waliul Islam, Hiroyasu Tsutsuki, Katsuhiko Ono, Ayaka Harada, Kozo Shinozaki, Takuro Niidome, Jun Fang, Tomohiro Sawa
Publikováno v:
ACS Applied Bio Materials. 5:5953-5964
The development of effective anticancer drugs is essential for chemotherapy that specifically targets cancer tissues. We recently synthesized a multifunctional water-soluble anticancer polymer drug consisting of styrene-maleic acid copolymer (SMA) co
Autor:
Ayaka Harada, Wei Xu, Katsuhiko Ono, Hiroyasu Tsutsuki, Kinnosuke Yahiro, Tomohiro Sawa, Takuro Niidome
Publikováno v:
ACS Applied Bio Materials.
Publikováno v:
Langmuir. 37:11484-11492
This paper reports the facile preparation of dual stimuli-responsive gel particles that simultaneously respond to weakly acidic and reducing stimuli and the application of these gel particles as a drug delivery carrier. The dual stimuli-responsive ge
Autor:
Kazuo Shin-ya, Yohei Katsuyama, Yasuo Ohnishi, Kaoru Sone, Toshio Moriya, Seiji Kawai, Ayaka Harada, Naoki Urano, Toshiya Senda, Masato Kawasaki, Naruhiko Adachi
Publikováno v:
Angewandte Chemie International Edition. 60:14554-14562
Nonribosomal peptide synthetases (NRPSs) are attractive targets for bioengineering to generate useful peptides . F moA3 is a single modular NRPS composed of heterocyclization (Cy), adenylation (A), and peptidyl carrier protein (PCP) domains. It use s