Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ayad M Al-Katib"'
Publikováno v:
Clinical Case Reports, Vol 8, Iss 9, Pp 1797-1801 (2020)
Abstract Ibrutinib is approved for chronic lymphocytic leukemia (CLL). However, its role in the treatment of multiple myeloma (MM) is not clear and is under investigation. We report a case of CLL that developed MM while on therapy with ibrutinib indi
Externí odkaz:
https://doaj.org/article/2cd589ba77954aa3940bc8329b6b53b1
Autor:
Ayad M, Al-Katib, Abdul Shukkur, Ebrahim, Mustapha, Kandouz, Feras, Zaiem, Ali, Raufi, Salah, Ebrahim, Anwar, Mohamed, Nada, Emara, Ali M, Gabali
Publikováno v:
Oncotarget
Non-Hodgkin’s lymphoma (NHL) is the most common hematological malignancy in the US. Many types remain incurable despite response to initial therapy and achievement of complete remission (CR). Advanced laboratory techniques like multicolor flow cyto
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(15)
We have previously reported that XK469 (2-[4-(7-chloro-2-quinoxalinyloxyphenoxy]-propionic acid) enhances topo IIalpha expression in WSU-WM cells in vitro [E. Mensah-Osman et al., Mol. Cancer Ther., 1: 1321-1326, 2002]. To test the hypothesis that XK
Publikováno v:
Molecular cancer therapeutics. 1(14)
Topoisomerase (Topo) IIalpha has proven to be an adequate anticancer target for tumors expressing this enzyme. In this study, we elucidated the effect of 2-[4-(7-chloro-2-quinoxalinyloxyphenoxy]-propionic acid (XK469; a new Topo IIbeta inhibitor) in
Publikováno v:
Molecular cancer therapeutics. 1(14)
The role of DNA topoisomerase (Topo) IIbeta in cancer chemotherapy remains unclear, although this particular isoform has been implicated in drug resistance. In this study, we investigated Topo IIbeta as a target for 2-[4-(7-chloro-2-quinoxalinyloxy)p
Autor:
Sanaa M, Nabha, Ramzi M, Mohammad, Mahmoud H, Dandashi, Brigitte, Coupaye-Gerard, Amro, Aboukameel, George R, Pettit, Ayad M, Al-Katib
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 8(8)
We have previously reported that combretastatin-A4 prodrug (CA4P), anantitubulin/antiangiogenic agent isolated from the South African willow tree Combretum caffrum, induced cell death primarily through mitotic catastrophe in a panel of human B-lympho
Publikováno v:
BMC Blood Disorders
BMC Blood Disorders, Vol 12, Iss 1, p 8 (2012)
BMC Blood Disorders, Vol 12, Iss 1, p 8 (2012)
Background Syncytial giant cell hepatitis (GCH) is an uncommon and an underreported disease entity. In two previously reported cases of GCH in patients with Chronic Lymphocytic Leukemia (CLL) liver failure ensued. Autoimmune and infective causes have