Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ayad A. Al-Hamashi"'
Publikováno v:
Iraqi Journal of Pharmaceutical Sciences, Vol 31, Iss Suppl. (2023)
One of these plants utilized in traditional medicine is Lactuca seriolla Linn., which belongs to the Asteraceae family. It goes by a variety of common names in the world, including prickly lettuce, wild lettuce, jagged lettuce, and Kahu and khas. The
Externí odkaz:
https://doaj.org/article/67ac611792d44ce8be1247d034c9ed77
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2709-2718 (2021)
Protein arginine methyltransferases (PRMTs) have been implicated in the progression of many diseases. Understanding substrate recognition and specificity of individual PRMT would facilitate the discovery of selective inhibitors towards future drug di
Externí odkaz:
https://doaj.org/article/94de89932623487b8bf535b282a1cf58
Publikováno v:
Biomolecules, Vol 11, Iss 6, p 854 (2021)
Protein arginine methyltransferases (PRMTs) play important roles in transcription, splicing, DNA damage repair, RNA biology, and cellular metabolism. Thus, PRMTs have been attractive targets for various diseases. In this study, we reported the design
Externí odkaz:
https://doaj.org/article/c59f26d06ce1427683212f1a6b6c56db
Publikováno v:
Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512). 31:54-61
One of these plants utilized in traditional medicine is Lactuca seriolla Linn., which belongs to the Asteraceae family. It goes by a variety of common names in the world, including prickly lettuce, wild lettuce, jagged lettuce, and Kahu and khas. The
Autor:
L. M. Viranga Tillekeratne, Ayad Ayad Al-Hamashi, Samkeliso Dlamini, William Taylor, Radhika Koranne, Mary Kay Pflum, Ahmed T. Negmeldin, Joseph Knoff
Publikováno v:
Proceedings, Vol 22, Iss 1, p 63 (2019)
Epigenetic regulation of gene expression without changing DNA sequences is a promising strategy in developing therapeutic agents for human diseases, especially cancer. [...]
Externí odkaz:
https://doaj.org/article/9185cc5d77694202988cc68711419b19
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2709-2718 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2709-2718 (2021)
Protein arginine methyltransferases (PRMTs) have been implicated in the progression of many diseases. Understanding substrate recognition and specificity of individual PRMT would facilitate the discovery of selective inhibitors towards future drug di
Autor:
Abdulateef Alqahtani, Ayad A. Al-Hamashi, Matthew Dunworth, Joseph R. Knoff, Robert A. Casero, Mary Kay H. Pflum, Lalith Perera, Endri Karaj, L. M. Viranga Tillekeratne, Radhika Koranne, Maisha S. Rashid, Samkeliso Dlamini, William R. Taylor
Publikováno v:
Bioorg Chem
Despite the advances in treatment strategies, cancer is still the second leading cause of death in the USA. A majority of the currently used cancer drugs have limitations in their clinical use due to poor selectivity, toxic side effects and multiple
Autor:
Qasim Alhadidi, Zahoor A. Shah, L. M. Viranga Tillekeratne, Ayad A. Al-Hamashi, Saroopa Samaradivakara, William R. Taylor, Radhika Samarasekera, O.V.D.S. Jagathpriya Weerasena, James T Slama, Shiroma M. Handunnetti, Lalith Perera
Publikováno v:
Journal of Natural Products. 81:1693-1700
A new resveratrol trimer, vateriferol (1), having four cis-oriented methine protons and constituting four contiguous stereocenters, was isolated from the bark extract of Vateria copallifera by bioassay-guided fractionation using a combination of norm
Publikováno v:
Biomolecules, Vol 11, Iss 854, p 854 (2021)
Biomolecules
Volume 11
Issue 6
Biomolecules
Volume 11
Issue 6
Protein arginine methyltransferases (PRMTs) play important roles in transcription, splicing, DNA damage repair, RNA biology, and cellular metabolism. Thus, PRMTs have been attractive targets for various diseases. In this study, we reported the design
Autor:
Ahmed T. Negmeldin, Christin L. Hanigan, L. M. Viranga Tillekeratne, Robert A. Casero, Jehad Almaliti, Ayad A. Al-Hamashi, Mary Kay H. Pflum, Lalith Perera
Publikováno v:
Journal of Medicinal Chemistry. 59:10642-10660
A number of analogues of the marine-derived histone deacetylase inhibitor largazole incorporating major structural changes in the depsipeptide ring were synthesized. Replacing the thiazole-thiazoline fragment of largazole with a bipyridine group gave