Výsledky vyhledávání - "Aya-Ebi Okubo Eneni"

Monosodium glutamate induces memory and hepatic dysfunctions in mice: ameliorative role of Jobelyn® through the augmentation of cellular antioxidant defense machineries

Autor: Prisilla O Nwokoye, Benneth Ben-Azu, Abayomi M. Ajayi, Solomon Umukoro, A.I. Omogbiya, Aya-Ebi Okubo Eneni, Anthony T. Eduviere

Publikováno v: Toxicological Research. 37:323-335

This study investigated the effect of high doses of monosodium glutamate (MSG), a known food additive on hepatic, memory and locomotor functions in mice, and the ameliorative potentials of Jobelyn® (JB), a unique dietary supplement. Twenty four male

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4eab3c25432f657c6160dae6cc5547ec
https://doi.org/10.1007/s43188-020-00068-9

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Diosmin attenuates schizophrenia-like behavior, oxidative stress, and acetylcholinesterase activity in mice

Autor: Adegbuyi Oladele Aderibigbe, Benneth Ben-Azu, Aya-Ebi Okubo Eneni, Abayomi M. Ajayi

Publikováno v: Drug Metabolism and Personalized Therapy.

Objectives Diosmin (DSM), commonly isolated from various plants, is a citrus nutrient that has been shown to increase intracellular antioxidant capacity and assuage symptoms associated with neurological disorders. Deficiency in the antioxidant system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b139cbe7d7b2de9c6062736f3b7fde
https://doi.org/10.1515/dmdi-2020-0119

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Monosodium glutamate induces memory and hepatic dysfunctions in mice: ameliorative role of Jobelyn

Autor: Adrian Itivere, Omogbiya, Benneth, Ben-Azu, Anthony Taghogho, Eduviere, Aya-Ebi Okubo, Eneni, Prisilla O, Nwokoye, Abayomi Mayowa, Ajayi, Solomon, Umukoro

Publikováno v: Toxicol Res

This study investigated the effect of high doses of monosodium glutamate (MSG), a known food additive on hepatic, memory and locomotor functions in mice, and the ameliorative potentials of Jobelyn(®) (JB), a unique dietary supplement. Twenty four ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cae5d873d783129b69d270485c989874
https://pubmed.ncbi.nlm.nih.gov/34295796

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Naringin Confers Protection against Psychosocial Defeat Stress-Induced Neurobehavioral Deficits in Mice: Involvement of Glutamic Acid Decarboxylase Isoform-67, Oxido-Nitrergic Stress, and Neuroinflammatory Mechanisms

Autor: Osagie Emokpae, Itivere Adrian Omogbiya, Olawumi M Oladapo, Aya-Ebi Okubo Eneni, Benneth Ben-Azu, Abayomi M. Ajayi, Ezekiel O. Iwalewa

Publikováno v: Journal of molecular neuroscience : MN. 71(3)

Psychosocial stress has been widely reported to contribute to psychiatric disturbances. Perturbations in the enzymes of GABAergic and cholinergic systems have been implicated as precursors in different stress-related neuropsychiatric diseases. Target

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae8da1abdf07870a2a7d038bc102815
https://pubmed.ncbi.nlm.nih.gov/32767187

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Involvement of GABAergic, BDNF and Nox-2 mechanisms in the prevention and reversal of ketamine-induced schizophrenia-like behavior by morin in mice

Autor: Solomon Umukoro, Adegbuyi Oladele Aderibigbe, Abayomi M. Ajayi, Aya-Ebi Okubo Eneni, Ezekiel O. Iwalewa, Benneth Ben-Azu

Publikováno v: Brain Research Bulletin. 139:292-306

GABAergic (Gamma-aminobutyric acid) and neurotrophic derangements have important implication in schizophrenia, a neuropsychiatric disease. Previous studies have shown that nicotinamide adenine dinucleotide phosphate oxidase (NADPH-oxidase) alters GAB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9ede8d40a0aa4e60e1bdb2e209c05e
https://doi.org/10.1016/j.brainresbull.2018.03.006

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Doxycycline Ameliorates Schizophrenia-Like Behaviors in Experimental Models in Mice by Targeting Underlying Oxidative Stress

Autor: Benneth Ben-Azu, Itivere Adrian Omogbiya, Aya-Ebi Okubo Eneni, Solomon Umukoro, Adegbuyi Oladele Aderibigbe, Ezekiel O. Iwalewa, Abayomi M. Ajayi

Publikováno v: Journal of Behavioral and Brain Science. :539-562

Current evidences support the inhibition of oxidative and inflammatory signaling mechanisms in the treatment of schizophrenia; as cure for this disease still remains limited. Doxycycline is a tetracycline antibiotic (a minocycline congener) with stro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::13352bc3f67e4f439402e3feef960776
https://doi.org/10.4236/jbbs.2016.613048

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Morin decreases cortical pyramidal neuron degeneration via inhibition of neuroinflammation in mouse model of schizophrenia

Autor: Ezekiel O. Iwalewa, Itivere Adrian Omogbiya, Olatunde Owoeye, Adegbuyi Oladele Aderibigbe, Benneth Ben-Azu, Solomon Umukoro, Aya-Ebi Okubo Eneni, Abayomi M. Ajayi

Publikováno v: International immunopharmacology. 70

Neuroinflammation plays a prominent role in the pathophysiology and progression of schizophrenia. Thus, suppression of neuroinflammation may retard the progression of the disease. This study was designed to investigate whether morin, a bioactive comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be1b9709e2b401acf50f233f5689363
https://pubmed.ncbi.nlm.nih.gov/33257235

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