Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Aya Nakae"'
Publikováno v:
Frontiers in Pain Research, Vol 5 (2024)
IntroductionThe new ICD-11 code for chronic pain indicates a direction to divide chronic pain into two categories: chronic secondary pain, which has a clear underlying disease, and chronic primary pain, which is associated with significant emotional
Externí odkaz:
https://doaj.org/article/1a88a7aad75b4a06a3bcca774b81d27b
Autor:
Yuka Yoshino, Yuta Fujii, Kazuhiro Chihara, Aya Nakae, Jun-ichiro Enmi, Yoshichika Yoshioka, Izuru Miyawaki
Publikováno v:
Toxicology Reports, Vol 12, Iss , Pp 1-9 (2024)
Drug-induced steatohepatitis is considered more serious than drug-induced hepatic steatosis, so that differentiating between the two is crucial in drug development. In addition, early detection of drug-induced steatohepatitis is considered important
Externí odkaz:
https://doaj.org/article/d3fe9ac1385942c88e0bb95af9ef75d6
Autor:
Yuka Yoshino, Yuta Fujii, Kazuhiro Chihara, Aya Nakae, Jun-ichiro Enmi, Yoshichika Yoshioka, Izuru Miyawaki
Publikováno v:
Toxicology Reports, Vol 10, Iss , Pp 481-486 (2023)
No method of monitoring drug-induced hepatic steatosis has been established, which is a concern in drug development. Hepatic steatosis is divided into diffuse and non-diffuse forms according to the pattern of fat deposition. Diffuse hepatic steatosis
Externí odkaz:
https://doaj.org/article/a62356ed7679451786ca40cbc0c7c706
Autor:
Yuta Fujii, Yuka Yoshino, Kazuhiro Chihara, Aya Nakae, Jun-ichiro Enmi, Yoshichika Yoshioka, Izuru Miyawaki
Publikováno v:
Toxicology Reports, Vol 10, Iss , Pp 97-103 (2023)
There are no specific and sensitive biomarkers for arteritis, and the occurrence of arteritis in nonclinical toxicological studies of a candidate drug makes development of the drug very difficult. However, we showed in a previous study that the high
Externí odkaz:
https://doaj.org/article/7b724274792644abb74bfb7db292f600
Publikováno v:
Gynecology and Minimally Invasive Therapy, Vol 11, Iss 2, Pp 110-113 (2022)
Hemorrhagic ovarian cysts (HOCs), a common gynecological disease causing intraabdominal bleeding, can be life threatening in patients undergoing antithrombotic therapy, especially those with left ventricular assist device (LVAD) implantation under st
Externí odkaz:
https://doaj.org/article/427f1887f9b8487fbb79511b755c0389
Autor:
Yuta Fujii, Yuka Yoshino, Kazuhiro Chihara, Aya Nakae, Jun-ichiro Enmi, Yoshichika Yoshioka, Izuru Miyawaki
Publikováno v:
Toxicology Reports, Vol 9, Iss , Pp 1595-1602 (2022)
A method capable of identifying drug-induced arteritis is highly desirable because no specific and sensitive biomarkers have yet been defined. Although magnetic resonance imaging (MRI) may be used to find a biomarker candidate for drug-induced arteri
Externí odkaz:
https://doaj.org/article/09f847ecd7ad4334bd6e543eb6c78d90
Autor:
Jessica E. Taylor, Hakwan Lau, Ben Seymour, Aya Nakae, Hidenobu Sumioka, Mitsuo Kawato, Ai Koizumi
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Externí odkaz:
https://doaj.org/article/18a3a3556edb4ec0aff0413836d01b91
Autor:
Jessica E. Taylor, Hakwan Lau, Ben Seymour, Aya Nakae, Hidenobu Sumioka, Mitsuo Kawato, Ai Koizumi
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Olfaction is an evolutionary ancient sense, but it remains unclear to what extent it can influence routine human behavior. We examined whether a threat-relevant predator odor (2-methyl-2-thiazoline) would contextually enhance the formation of human f
Externí odkaz:
https://doaj.org/article/8de22e24e8b0449aa5a63db1d9b20c1a
Autor:
Kenji Miki, Aya Nakae, Kenrin Shi, Yuka Yasuda, Hidenaga Yamamori, Michiko Fujimoto, Manabu Ikeda, Masahiko Shibata, Masao Yukioka, Ryota Hashimoto
Publikováno v:
Neuropsychopharmacology Reports, Vol 38, Iss 4, Pp 167-174 (2018)
Abstract Aim To explore the characteristics of psychiatric morbidity in chronic pain patients who present with or without fibromyalgia. Methods Patients are referred to our chronic pain clinic from primary medical institutions, as we are a secondary
Externí odkaz:
https://doaj.org/article/53bdd37a59fc46f59411181b8b92a9da
Autor:
Hiroaki Mano, Gopal Kotecha, Kenji Leibnitz, Takashi Matsubara, Christian Sprenger, Aya Nakae, Nicholas Shenker, Masahiko Shibata, Valerie Voon, Wako Yoshida, Michael Lee, Toshio Yanagida, Mitsuo Kawato, Maria Joao Rosa, Ben Seymour
Publikováno v:
Wellcome Open Research, Vol 3 (2018)
Background. Chronic pain is a common, often disabling condition thought to involve a combination of peripheral and central neurobiological factors. However, the extent and nature of changes in the brain is poorly understood. Methods. We investigated
Externí odkaz:
https://doaj.org/article/e3ad2321809043a19357599500cec415