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Fingolimod ameliorates imiquimod-induced psoriasiform dermatitis by sequestrating interleukin-17-producing ?d T cells in secondary lymph nodes

Autor: Aya Mitsui, Teruo Shimizu, Yayoi Tada, Shinichi Sato, Iori Okura, Yoshihide Asano, Masahiro Kamata

Publikováno v: Journal of Dermatological Science. 102:116-125

Background Psoriasis is a chronic inflammatory skin disease. Interleukin (IL)-17A plays a key role in the pathogenesis of psoriasis. Fingolimod, which is available for the treatment of multiple sclerosis, exerts anti-inflammatory effects by sequestra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2380c65e634973aace7cfd7837ceb2e2
https://doi.org/10.1016/j.jdermsci.2021.04.004

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The vitamin D3 analog, maxacalcitol, reduces psoriasiform skin inflammation by inducing regulatory T cells and downregulating IL-23 and IL-17 production

Autor: Yayoi Tada, Makoto Sugaya, Shinichi Watanabe, Shintaro Takeoka, Takafumi Kadono, Yoshihide Asano, Teruo Shimizu, Aya Mitsui, Masahiro Kamata, Carren Sy Hau, Sayaka Shibata, Shinichi Sato

Publikováno v: Journal of Dermatological Science. 92:117-126

Background Psoriasis is a Th1/Th17-mediated inflammatory dermatosis treated with topical corticosteroids and vitamin D3 analogs (VD3 As). Objective To compare the effects of a VD3 A maxacalcitol and betamethasone valerate (BV) steroid lotion on topic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de2a7f300472e9037c657bcef5632793
https://doi.org/10.1016/j.jdermsci.2018.08.007

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Assessment of endothelial function during the loading phase of infliximab in psoriasis: a potential predictor of its drug survival

Autor: Yohei Ichimura, Ayumi Yoshizaki, Momoko Nakao, Rino Shida, Takehiro Takahashi, Masahiro Kamata, Mayuko Araki, Rei Watanabe, Sayaka Shibata, Kouki Nakamura, Arisa Ito, Yoshihide Asano, Takemichi Fukasawa, Aya Mitsui, Shinichi Sato

Publikováno v: International journal of dermatology. 58(1)

Background Tumor necrosis factor inhibitors decrease the risk of cardiovascular events in moderate to severe psoriasis, but the association between their effects on endothelial function and those on skin lesions has not been well studied. We investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2abb969a46f3b11a6d65f60a302fb7
https://pubmed.ncbi.nlm.nih.gov/30168849

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Serum IL-33 levels are increased in patients with psoriasis

Autor: Tomomitsu Miyagaki, Sayaka Shibata, S. Sato, Makoto Sugaya, Aya Mitsui, Hideki Fujita, Yayoi Tada, Masahiro Kamata, Yoshihide Asano, Takuya Takahashi, Takafumi Kadono

Publikováno v: Clinical and Experimental Dermatology. 41:183-189

Summary Background Interleukin (IL)-33 is a recently identified cytokine, which is a member of the IL-1 family and binds to a heterodimeric receptor comprising ST2 (suppression of tumorigenicity 2) and IL-1 receptor accessory protein. Serum levels of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb89f030ef373440b5c32dfab2bc7cbc
https://doi.org/10.1111/ced.12670

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Deficiency of both L-selectin and ICAM-1 exacerbates imiquimod-induced psoriasis-like skin inflammation through increased infiltration of antigen presenting cells

Autor: Shinichi Sato, Akihiko Asahina, Carren Sy Hau, Masahiro Kamata, Sayaka Shibata, Yayoi Tada, Aya Mitsui

Publikováno v: Clinical Immunology. 157:43-55

To assess the role of inter-cellular adhesion molecule (ICAM)-1 and L-selectin in psoriasis pathogenic process, we examined the psoriasiform skin inflammation triggered by imiquimod, a toll-like receptor 7/8 agonist, in mice lacking ICAM-1 (ICAM-1(-/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0659703cbb3b7b3d376e5e430bf11eb3
https://doi.org/10.1016/j.clim.2014.12.011

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Facile Synthesis of Diethyl Azodicarboxylate and Diethylhydrazodicarboxylate via the Sequential Bromination and Hofmann-Type Rearrangement of Ethyl Allophanate

Autor: Hideo Tanaka, Aya Mitsui, Kazutaka Nishino, Futaba Hara, Haruka Yahagi, Tomoko Suzuki, Manabu Kuroboshi, Hiromu Kawakubo, Masato Onodera, Hiroyuki Takayama, Tomoyoshi Takano, Yoshito Takebayashi

Publikováno v: Synthetic Communications. 45:1068-1072

Diethyl azodicarboxylate (DEAD) is a well-known coupling reagent that can be readily synthesized from diethylhydrazodicarboxylate (DEHD). The bromination of commercially available ethyl allophanate (1) in CHCl3, followed by the Hofmann-type rearrange

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1743c0916b7b06c4a1aa63b4e1f79df2
https://doi.org/10.1080/00397911.2014.1002137

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The vitamin D

Autor: Carren Sy, Hau, Teruo, Shimizu, Yayoi, Tada, Masahiro, Kamata, Shintaro, Takeoka, Sayaka, Shibata, Aya, Mitsui, Yoshihide, Asano, Makoto, Sugaya, Takafumi, Kadono, Shinichi, Sato, Shinichi, Watanabe

Publikováno v: Journal of dermatological science. 92(2)

Psoriasis is a Th1/Th17-mediated inflammatory dermatosis treated with topical corticosteroids and vitamin DTo compare the effects of a VD3 A maxacalcitol and betamethasone valerate (BV) steroid lotion on topical imiquimod (IMQ)-induced psoriasiform s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::25f948c2d5688ea46196920acf6e113b
https://pubmed.ncbi.nlm.nih.gov/30166055

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ICAM-1 Deficiency Exacerbates Sarcoid-Like Granulomatosis Induced by Propionibacterium acnes through Impaired IL-10 Production by Regulatory T Cells

Autor: Tomomitsu Miyagaki, Yayoi Tada, Sayaka Shibata, Yoshihide Asano, Shinichi Sato, Masahiro Kamata, Makoto Sugaya, Takafumi Kadono, Aya Mitsui

Publikováno v: The American Journal of Pathology. 183:1731-1739

Propionibacterium acnes has been implicated as one of the suggested causative antigens for sarcoidosis, a systemic granulomatous disease. By injecting heat-killed P. acnes into the dorsal skin of C57BL/6J mice on days 1, 3, 5, and 14, sarcoid-like gr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff7883a48b02bcfe5f51d4b0e8af36c
https://doi.org/10.1016/j.ajpath.2013.08.021

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The development of chronic inflammatory demyelinating polyneuropathy during adalimumab treatment in a patient with psoriasis vulgaris

Autor: Yoshihide Asano, C. Toyoda, Rino Shida, Takehiro Takahashi, Kouki Nakamura, Yuko Ikawa, Momoko Nakao, Ayumi Yoshizaki, Hisayoshi Oka, Mayuko Araki, Sayaka Shibata, Rei Watanabe, Aya Mitsui, Shinichi Sato

Publikováno v: European journal of dermatology : EJD. 26(4)

We report a case of psoriasis vulgaris in which chronic inflammatory demyelinating polyneuropathy (CIDP) developed during adalimumab treatment. A 42-year-old Japanese man with a history of juvenile-onset psoriasis, who had been treated with topical v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1182c998d07607be21d036f8e96ed8
https://pubmed.ncbi.nlm.nih.gov/27086491

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